What’s in cbd oil

Contents

CBD Oil – Uses & Benefits

CBD is everywhere these days. The Cannabis Company’s CEO Dr. David Stapleton decided to examine the research surrounding its use in treating illnesses affecting millions of Australians. What we discovered is a building body of evidence for CBD oil benefits. So what are the uses and benefits of CBD oil in Australia?

Let’s start by answering the most common question: no, CBD WILL NOT GET YOU HIGH. This is because it’s not psychoactive. “Psychoactive” substances affect the way you think and feel, which can affect the way you behave. Common legal psychoactive drugs are alcohol, tobacco and various prescription medications. THC is psychoactive, which is where the confusion around CBD comes from – marijuana contains both CBD and THC.

So if CBD does NOT affect the way you think, feel and behave, what does it do?

CBD is used in the treatment of anxiety, depression, schizophrenia, cancer, nausea, vomiting, eating disorders, pain, arthritis, inflammation, epilepsy and seizures

According to the British Journal of Clinical Pharmacology, the most common uses of CBD are in the treatment of anxiety, schizophrenia, nausea, vomiting, inflammation and epilepsy. The most common proven benefits of CBD include:

Pain, Inflammation & Arthritis

Natural pain relief is perhaps the most common use for CBD. With an opioid epidemic currently taking place in Australia, many chronic pain sufferers are turning to a safer option: cannabis.

According to this 2012 study published by the Journal of Experimental Medicine, CBD may represent a significant step forward in the treatment of chronic pain, especially in those suffering from MS (multiple sclerosis). This is because CBD inhibits neuronal transmission in pain pathways, which is a fancy way of saying “it stops the message getting through”, as this is what pain is: a message from your brain to your body that something’s wrong. This is useful in everyday life (when you cut or burn yourself, it’s a message to STOP!), but when pain becomes chronic and requires constant treatment, removing it through CBD can be a life-changing experience. Tens of thousands of Aussies have already experienced this, and yet our government continues to insist on criminalising these innocent people. A further inflammation-related ailment which almost 4 million Australians suffer from is arthritis. As this article demonstrates, CBD helps arthritis in many ways.

Anxiety & Depression

Beyond Blue reports that 1-in-5 Australians experience mental health challenges in any given year, while almost 1-in-2 will deal with a mental health condition during their lifetime. Since three million Aussies currently live with depression or anxiety, it’s no wonder that many of them are turning away from expensive and debilitating pharmaceutical products to find a natural solution. The side effects of pharmaceuticals include sexual dysfunction, agitation, headaches, drowsiness and insomnia, while common medications such as benzodiazepine are highly addictive and often introduce users to whole new set of worries.

CBD represents a whole new approach mental health challenges, from mild anxiety all the way up to crippling depression. This 2011 study had a fascinating outcome; it set up a scenario in which 24 people who had never tried CBD were studied in a public speaking test. An hour and a half before the test commenced, people were given either CBD or a placebo. Those who received the placebo demonstrated high levels of anxiety, stress and cognitive impairment, while those who had received CBD saw all of those symptoms significantly reduced. In short, they simply relaxed and calmed down.

According to this research published in the Brazilian Journal of Psychiatry, people suffering from social anxiety disorder strongly benefit from CBD. The researchers suggest that CBD may be an effective treatment for PTSD (post-traumatic stress disorder), obsessive compulsive disorder and panic disorder.

Cancer

Responsible for 3-in-10 deaths, cancer is the second most common cause of death in Australia. Sufferers are increasingly turning to CBD not just for its treatment of cancer itself, but for relief from the crippling effects of chemotherapy. There are a number of studies which demonstrate CBD’s considerable strength in treatment of cancer; in both this study and this one CBD attacked only the cancerous cells and inhibited their growth, while leaving the non-cancer cells alone – a far better solution than chemo, which ravages the body of those who undergo it.

Nausea, Vomiting and Eating Disorders

In this 2012 study the British Journal of Pharmacology proved that CBD helps to remove nausea and vomiting, something which folk medicine practitioners have known for millennia. The effects are often quite dramatic, leading to long-lasting and sustained relief. This is another way in which CBD helps cancer patients, as chemotherapy often results in nausea and lack of appetite. This is why it’s likewise helpful in cases of bulimia and anorexia nervosa.

Epilepsy & Seizures

With between 3% and 3.5% of Australians experiencing epilepsy at some point in their lives, over 250,000 Australians currently live with epilepsy. Often, the most heartbreaking cases are those which involve children, who represent approximately 40% of the population suffering from epilepsy.

In 2014 Stanford University conducted a survey that demonstrated dramatic results in children affected by seizures. Before using CBD, 63% of the children had been treated with anti-epileptic pharmaceutical medication. 84% of the children saw a reduction in their seizure frequency while taking CBD. 11% completely stopped seizing, 42% saw massive benefits (a reduction in seizure frequency of over 80%), and 32% saw a reduction in seizures of 25-60%. Although side-effects included drowsiness and fatigue, there were other reported benefits in terms of mood, alertness and sleep.

Diabetes

An estimated 5.1% of Australians are diagnosed with diabetes – that’s 1.2 million Aussies over the age of 2. Many suffer needlessly, and CBD is providing many with new hope.

Between 2005 and 2010, a study published in the American Journal of Medicine examined almost 5,000 adults. The results were impressive: marijuana use was associated with 16% lower insulin levels. Additionally, smaller waist circumferences were linked to marijuana use, which is a crucial factor in preventing the onset of diabetes.

The Challenges Around CBD

The main issue with CBD is that much of the scientific research which has been done on it is through analysis of its effects on mice, instead of humans. Quite aside from ethical issues around animal testing, the fact is that humans are different, and our bodies don’t always react the same as other animals. This is why responsible testing needs to occur in order to find out everything we can about its uses, benefits and side-effects.

More widely speaking, a number of studies have shown that long-term recreational use of cannabis can have negative effects on mental health. Frontiers in Psychiatry published a report in 2013 which claims that permanent psychological disorders can be linked with cannabis, depending on frequency of use, the potency of the cannabis used, the age someone begins using and the sensitivity of the individual in question.

The vast majority of recreational cannabis users never have to worry about such things, but in some rare cases, there can be undesirable effects such as anxiety and paranoia. Encouragingly, studies are beginning to show that CBD counteracts these adverse effects, but more research is needed.

Article written by Cormac Sheehan.

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DOCTORS are now able to prescribe cannabis oil to patients in a long-awaited change to regulations.

It comes as two medicines made from the cannabis plant have been recommended for use on the NHS for the first time.

3 Cannabis oil is thought to help a number of ailmentsCredit: EPA

What is cannabis oil and is it legal in the UK?

CBD cannabis oil is a substance extracted from the cannabis plant by steam distillation.

Cannabis oil is usually consumed orally, and has a very distinct taste.

This low-concentrate version of the oil is available to buy in the UK and is not illegal.

Products are required to contain less than 0.05% THC.

THC (or Tetrahydrocannabinol) is the psychoactive component in cannabis that makes users feel “high”.

Two cannabis-based drugs that help with epilepsy and MS have been approved for the NHS.

Epidyolex is recommended for two rare types of epilepsy while the spray Sativex can ease muscle spasms in multiple sclerosis.

3 Cannabis oil will now be available on prescription from doctors in England, Scotland and WalesCredit: Alamy

What is cannabis oil used for?

Cannabis oil can be beneficial in a variety of ways, from helping promote sleep to boosting appetite and reducing stress, anxiety and depression.

It is also said to have skincare benefits, such as preventing signs of ageing and protecting against eczema and psoriasis, so can also be applied to the surface of the skin.

Though research is limited, there is evidence to support the idea that medical marijuana, which contains small amounts of the illegal compound THC, can alleviate some of the side-effects of cancer treatment including nausea during chemotherapy.

And while it is different, some accounts from users have claimed to find similar benefits from using cannabis oil, though this has never been scientifically backed by doctors, so is not advised as an alternative to other treatments.

One type of oil or Cannabidol is CBD which has been promoted as a possible treatment method for those living with addiction or anxiety.

However CBD products – while legal – have not been approved for use in the US and there are possible side effects including irritability and nausea.

3 Low-concentrate CBD oil is said to be beneficial for promoting sleep, boosting appetite and reducing anxiety, stress and depressionCredit: Reuters

When will it be available on prescription?

Campaigners have welcomed the go-ahead but said thousands of other people who could benefit from cannabis-based medicines were left in limbo.

Millie Hinton, from the group End Our Pain, said it had been “a massive missed opportunity”.

Last year, it was made legal for doctors to prescribe medicinal cannabis.

However, many have been reluctant to do so, citing a lack of guidance and costing concerns.

It has forced some families to buy the drugs abroad and bring them into the UK illegally.

The latest guidance comes after the National Institute for Health and Care Excellence looked at the effectiveness of cannabis-based medicines for several conditions.

It decided up to 9,000 people with Lennox-Gastaut and Dravet syndromes and 10,000 MS sufferers can be prescribed the two drugs.

But Nice drew the line at drugs containing THC — the psychoactive ingredient in cannabis — to relieve pain.

Is cannabis oil illegal in the UK, is it different from concentrated CBD oil and can it be used to treat cancer?

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CBD Oil: Risks, Side Effects And What You Need To Know

  • CBD oil is generally safe to take, but there may be risks and side effects
  • How CBD oil may react with your other medications
  • Who shouldn’t take CBD oil?

For many of us, it may seem as though cannabidiol (CBD) sprang up out of nowhere. Within a few short years, this obscure molecule found in cannabis plants has moved from near-anonymity to a cure-all embraced by millions.

From college campuses to retirement homes, everyone’s talking about CBD, leaving many to speculate about when the other shoe will drop, revealing some negative aspect to the health trend.

Although CBD might be a new molecule to you, scientists have been studying it since the 1970’s, alongside its infamous sister molecule, THC. For the past few decades, lawyers, doctors, patients and politicians have all been pitting the medical potential of cannabis against its risk for recreational abuse. But all the while, evidence has been mounting that CBD offers similar — if not better — medical benefits without the downside of a “high” from THC.

Even a critical review by the World Health Organization (WHO) recently reported that CBD is a promising treatment for a number of medical conditions, is well tolerated, has a good safety profile, and doesn’t appear to be a risk for abuse, dependence, or other public-health related problems. In other words, even the WHO thinks CBD is A-OK.

When looking through the thousands of scientific articles referencing CBD, it’s very difficult to find any evidence of dangerous side effects or contraindications. However, widespread use of concentrated CBD is a very new phenomenon, and your safety is our priority.

So we thought we’d compile all the negative scientific evidence into one handy guide, to help you decide whether CBD is right for you. We’ll cover the different side effects you might encounter and what they could mean, as well as what current research says about trying CBD if you are:

  • Immune-compromised
  • Currently taking prescription drugs
  • Pregnant or trying to conceive
  • … and more

Clinical evidence for CBD oil

CBD critics are absolutely correct when they state that definitive clinical evidence is lacking to recommend CBD for many of the reasons people currently take CBD products. CBD is currently available as an FDA-approved prescription treatment (called Epidiolex) for two rare forms of childhood epilepsy. But in order to gather the clinical evidence required for this status, the manufacturer needed to pay for almost two decades of research and clinical trials.

Now that Epidiolex has opened the door for CBD’s acceptance by the medical community, you can expect to see more prescription uses for CBD in the future. However, because of the way our medical system is structured, the stamp of approval can only be gained after a long period of costly clinical testing. This testing is paid for by companies that can patent and profit from the results.

In the absence of definitive, slam-dunk clinical evidence, what the general CBD community does have to work with is a great deal of preliminary scientific evidence from laboratory experiments, animal models and case studies. Hundreds of scientific papers are published annually on cannabidiol, and the vast majority continue to point at CBD’s safety & efficacy for a wide range of conditions. This preliminary scientific evidence — from animal studies and human case studies — is what gets the ball rolling towards clinical trials.

If you check the US government’s clinical trials database, you’ll see that more than 50 trials are either currently active or recruiting participants for conditions ranging from arthritis to drug abuse disorders. (Foria is participating in this movement with a 400-person study on the efficacy of our CBD suppositories for menstrual cramps and pain — although this isn’t a clinical trial, but a less-expensive self-reported survey.)

These trials will double the number of preexisting clinical trials that have been carried out for cannabidiol, and it’s just the beginning. Will some of the promising benefits of CBD prove wrong when tested clinically? Most likely. People are currently trying to treat countless conditions with CBD, and it’s likely that a few of them might not be any more effective than placebo when tested with clinical trials.

So yes, you may be jumping the gun by taking CBD to address a health issue when its use is not yet supported by clinical evidence that would pass muster with the FDA. But that clinical evidence won’t be available any time soon, and many people don’t want to wait a decade before finding out for themselves if CBD is effective for their needs.

Side effects based on high-dose clinical trials

Because we lack clinical evidence in favor of CBD, we also lack clinical evidence against CBD. From the few clinical trials that have been conducted, no conclusive severe side effects have surfaced.

The most comprehensive results available are based on Epidiolex, the FDA-approved CBD drug for childhood epilepsy. During clinical trials, youths between ages 2 and 18 were prescribed high daily doses of CBD for 14 weeks. The daily doses were equivalent to 1,360 mg for a 150-pound adult — more than is typically found in an entire bottle of CBD oil.

These are the side effects they most often experienced:

  • Tiredness
  • Decreased appetite
  • Gastrointestinal problems
  • Altered liver enzymes (see following section for more on liver enzymes)

For most patients, these side effects occurred during the first few weeks while they were quickly raising their dosage. The symptoms typically subsided after their dosage stabilized, and lowering the dose was also an effective way of decreasing undesirable side effects. If you’re experiencing any of these side effects on your current CBD product, you might experiment with waiting it out a week, lowering your dose or trying a different type of product entirely.

If you’re experimenting with high doses of CBD, we recommend reading more about what scientists learned from the Epidiolex trials. You can find the results of their 120-person clinical trial here and their FDA documentation here.

Side effects from dishonest CBD products

Clinical trials give patients high-quality, safe products which contain a reliable quantity of CBD. The Epidiolex side effects are ones you might expect from a high dose of a very pure product. On the other hand, because the supplement industry in the US isn’t heavily regulated, if you purchase CBD from dishonest or potentially unsafe manufacturers, you might experience very different side effects. In fact, when scientists recently tested a variety of publicly-available CBD products, only 31% were accurately labeled.

What can these unreliable products contain?

  • Pesticides and heavy metals from bad farming practices
  • High levels of THC (more than desired)
  • Synthetic cannabinoids
  • Any kind of contaminants (mold, bacteria, rancidity, etc)

Sometimes CBD products don’t contain any CBD at all — in which case you won’t experience any effects, positive or negative.

True CBD products are prepared from hemp plants, which can contain trace quantities of THC unless that’s removed during extraction. If a product contains high levels of THC, you might experience side effects like dry mouth, hunger, or altered mood and thinking.

Although it’s hard to imagine all the different side effects you might experience from contaminated or synthetic products, the worst effects of dishonest CBD products could be long-term damage to your body that you won’t immediately experience as a side effect.

If you’re suspicious about the safety of your current CBD products, do yourself a favor and throw them away. CBD oil is a concentrated plant-based extract that goes into your body — expect its quality to be at least as high as the foods you eat.

CBD Contraindications: preliminary scientific research

Although CBD has been deemed safe by the WHO and other health organizations, not enough experiments have been done to identify if there are any populations for whom CBD is unsafe. Instead of taking that as a free pass to tell everyone to take CBD (like most other CBD companies), we think this makes it even more important to scour the scientific literature for any warning signs. Because we value your safety first, we put together a list of all the conditions we could find that might deserve special consideration.

Here’s what the evidence shows about taking CBD if:

You take prescription drugs. (Could be important) Pharmaceutical drugs are processed by your body in different ways; some are less effective after processing, while others aren’t effective until after they’ve been processed. Similar to grapefruits, CBD can occupy enzymes (cytochrome p450) that your body uses to process certain pharmaceutical drugs. Taking CBD alongside these pharmaceuticals could pose a health risk by either increasing or decreasing levels of these medications in your bloodstream. If you currently take prescription drugs — particularly *any that come with a warning not to consume with grapefruit* such as warfarin, anti-epileptics, HIV antivirals, chemotherapy and others — we suggest speaking with a medical professional before incorporating CBD into your wellness routine. They could help you understand potential interactions and how to proceed.

You have complications with your liver. (Could be important) This warning is speculative, but people who have liver problems might want to be cautious about their CBD intake. During the clinical trial of Epidiolex, children taking CBD were more likely to have elevated liver enzymes (ALT and AST aminotransferases). In CBD’s defense, all of these children were also taking pharmaceuticals known to damage the liver. It’s currently unclear whether CBD directly affects the liver — or if the interaction with pharmaceuticals (mentioned above) results in higher bloodstream levels of liver-damaging prescription drugs. However, just to be safe, if you suffer from liver problems or take medication that is hard on your liver, you might want to monitor your liver enzymes when introducing CBD into your daily routine. Epidiolex additionally suggests that people with liver impairments slowly increase their CBD doses. They also reported that elevated liver enzymes were primarily observed in children taking the maximum dose, and lower doses (680 mg or less per day for a 150-pound person) posed a much lower risk.

You have low blood pressure. (Could be important) Some studies report that CBD lowers blood pressure, which could be a concern for people already dealing with low blood pressure. Overall, CBD appears most effective at reducing blood pressure during stressful events, which is widely embraced as one of its benefits. But CBD might also temporarily decrease your resting blood pressure as well. If you suffer from hypotension, you might want to monitor your blood pressure when trying new CBD products or increasing your dose. Are you the type that gets a bit light headed when you stand up suddenly? Just be a bit more cautious if you’ve just used a CBD vape pen or if you’ve been taking high oral doses of CBD.

You’re trying to conceive. (Not enough evidence) Natural cannabinoids are produced and used throughout our bodies as messengers. One of their most important uses is to help our bodies coordinate conception and pregnancy. At the moment, it’s a complete mystery what extra cannabinoids do to our bodies’ reproductive capabilities. Some evidence suggests that regular cannabis users have slightly lower fertility rates, although more comprehensive assessments of the data generally agree that this effect is minimal at most — and is more likely caused by THC than CBD. However, if you are having difficulty conceiving, discuss your use of CBD or cannabis products with your doctor.

You’re pregnant or breastfeeding. (Could be important) When pregnant or breastfeeding, a mother shares everything with her growing child. Active molecules in a mother’s bloodstream can pass into her child’s body through both the placenta and breast milk. Broad screening reveals that cannabinoids can be detected in the umbilical cords and stools of newborn children. And low levels of cannabinoids can be detected in breast milk from regular cannabis users. It’s currently uncertain if/how CBD affects a developing baby, but it’s safest to minimize exposure to cannabinoids (and a wide variety of other foods, products, and medications) while pregnant or breastfeeding. If you are currently pregnant or breastfeeding and use CBD to manage anxiety or another health issue, discuss the tradeoffs with a medical professional.

You’re immune compromised. (Most evidence disproves this concern) CBD is known as an immunomodulator because it can calm down a hyperactive immune system, but some worry this could harm people whose immune systems are already impaired, like HIV sufferers. Although we don’t have evidence specifically testing CBD against this fear, many studies have been done using the whole cannabis plant. Research shows that cannabis helps relieve pain and other HIV-related symptoms without causing severe side effects. And when marijuana is tested against specific HIV symptoms like liver fibrosis, cannabinoids do not appear to worsen it. Although current evidence suggests that CBD could be more helpful than harmful for immune-compromised individuals, the jury is still out.

You’re surrounded by germs. (Not enough evidence) Some people hypothesize that CBD’s excellent immune-system soothing capabilities could accidentally let a few stray germs slip past your immune system’s defense. Scientists have tested this by exposing mice to the bacterium that causes Legionnaires’ disease and measuring their ability to fight the infection. Although moderate doses of CBD didn’t impair their immune systems, they were worse off on high doses equivalent to 1,000 mg for a 150 pound person. If you’re currently taking higher doses of CBD and also sharing space with a bunch of coughing people, it might be a good idea to temporarily decrease your CBD dose.

You want to replace a current treatment with CBD. (Very important!) We absolutely love CBD and have heard from countless enthusiasts who’ve been able to cut back on pharmaceuticals with the assistance of CBD. That said, please do not substitute any current medications or prescribed treatments with CBD unless it’s with the approval of a medical professional. Our hope is to provide you with extra support, not to replace the supports you already have in place. Life can be difficult to manage alone, and in times of need, we encourage you to seek all the medical and emotional assistance available.

Written by: Genevieve R. Moore PhD

CBD Side Effects: Things You Should Know!

Exploring the Advantages and Disadvantages of CBD

The CBD market is growing at lightning speed. Each report released on the industry seems to add a few extra billions to the overall value of the market. The marijuana industry analysts believe it could reach $22 billion per year by 2022!

There is no question that reputable brands within the industry will make their fortunes over the next few years. Yet, despite the hype, how much do we really know about cannabidiol? Research is ongoing, and so far, it has been touted as a safe alternative to prescription medication for dozens of symptoms associated with conditions such as Parkinson’s, PTSD, epilepsy, and multiple sclerosis.

For a public still cautious about the psychoactive effects of marijuana, the fact that CBD doesn’t provide a high, is a major selling point. It makes it more available to children, for example, and is quickly being seen as a viable treatment for a wide range of things.

In December 2018, President Trump signed the Farm Bill into law. It removed hemp, and any cannabinoids derived from the plant, from the Controlled Substances Act. This has made hemp-derived CBD available legally in all 50 states.

If you browse through the articles on this website, you will find a myriad of information on the possible benefits of CBD. In this piece, however, we aim to bring some balance to the equation by taking a look at the possible side effects of CBD.

Common Misconceptions About CBD

In an emerging industry, there are always going to be hucksters peddling snake oil and enough misinformation to fill Harvard’s library. There are dozens of misconceptions about this cannabinoid, but I am only going to outline five!

1 – CBD Isn’t Psychoactive

Often CBD sellers claim that CBD is non-psychoactive. This is likely due to a misunderstanding of what psychoactive means.

A substance is deemed ‘psychoactive’ if it affects a person’s mood or behavior. Research has clearly shown that CBD has a myriad of effects including antidepressant and anxiety-reducing effects, and is thus psychoactive.

CBD would be better described as ‘non-intoxicating’ as it doesn’t have the typical effects of intoxication that THC does.

2 – CBD Isn’t Regulated by the FDA

While the Farm Bill is great news for industrial hemp farmers, it does not prevent the FDA from regulating dietary supplements, drugs, cosmetics, and food, including those that contain hemp.

It recently approved Epidiolex, which includes a purified form of CBD, and Sativex; a pharmaceutical drug that contains THC and CBD. Therefore, while the FDA hasn’t regulated the cannabinoid CBD, it has already approved two drugs that contain it!

3 – CBD Is Legal in All 50 States

Technically, industrial hemp is legal to grow in the United States thanks to the 2018 Farm Bill that took hemp and its derivatives off the controlled substances list.

As alluded to above, CBD can be derived from hemp or marijuana. The main difference between the two is that hemp-derived CBD has less than 0.3% THC. So thanks to the Farm Bill, hemp-derived CBD is legal in all 50 states. The misconception, though, is that ALL CBD is legal nationwide. Marijuana-derived CBD is still illegal anywhere marijuana is illegal.

And it should also be noted that there is no guarantee that you’ll pass a drug test if you consume a full-spectrum CBD product, as there may still be detectable traces of THC.

4 – CBD Is Relatively Unresearched

While it is true that there haven’t been a huge number of clinical trials, CBD has been researched in dozens of countries around the world. One Brazilian study in 2017 found that CBD made people less anxious when faced with a public speaking task. A UK study in 2018 showed exciting results when testing CBD on people with ulcerative colitis.

And the list continues. Now that the federal ban on hemp and its cannabinoids has been lifted, we should see a significant amount of research into CBD in the next few years.

5 – CBD Is Dubious Because the Market Is Dodgy

It is absolutely true that the CBD industry is poorly regulated, and that there are con men selling olive oil labeled as CBD and making money from uneducated buyers.

However, the unregulated state of the market does NOT mean that the compound itself is ineffective. Hundreds of thousands of people who have used CBD and are delighted with the results. And research is backing what users have been reporting for years. So the onus on buyers is to do their research to ensure they’re getting high-quality CBD.

The Potential Side Effects of CBD

Perhaps the biggest danger associated with the CBD market is the lack of regulation. Pretty much anyone can set up a company, slap a label on a bottle, and put whatever they like inside it. Back in 2017, one study discovered that almost 70% of CBD products didn’t contain the amount of marijuana extract promised on the label. About one-quarter contained too much CBD, while 43% contained too little. 20% of the samples tested positive for THC.

So it’s important to make sure you buy well-labeled CBD from a reputable company that can support and prove its claims with third-party lab reports.

If you’re using CBD from organically grown hemp (without pesticides, GMOs, and insecticides) into your body, the reported side effects are few and far between. However, there are a few so let’s delve into them.

Potential Liver Damage

Aside from alcohol and drugs, even natural supplements can take their toll on the liver if used to excess. A recent study found that CBD could cause liver damage, but the doses given to subjects were significantly higher than what the average consumer takes. Still, if one has liver damage or is on other potentially liver-toxic drugs, it’s best to monitor your liver enzymes while on CBD.

Interactions with Other Drugs

There is also evidence that CBD could interact with other medications, especially when used in high doses. One of the most salient examples is Warfarin, the well-known anticoagulant. It was also found to increase levels of anti-seizure medications. Thus, it’s important to monitor the levels of other drugs in someone taking CBD.

Pregnant Women Think Twice

Very little research has been done on CBD in pregnancy and therefore it is not recommended to consume CBD during pregnancy. This is especially important due to the unknown potential side effects CBD can have on the fetus.

Dry Mouth

This is a common issue with practically all marijuana and hemp strains. It is generally due to the Endocannabinoid System’s (ECS) inhibition of salivary secretion. Fortunately, if you experience dry mouth, drinking some fluids should mitigate what is a fairly low-key side effect.

Drowsiness

Drowsiness is a potentially much significant side effect. If you plan on driving or operating heavy machinery, it isn’t a good idea to use CBD beforehand, especially if you don’t know how it is going to affect you. The truth is, CBD can affect people in different ways and depending on what dose they took. While your friend may experience a burst of energy while feeling invigorated, whereas you could feel drowsy and listless.

Falling Blood Pressure

A study by Jadoon, Tan, and O’Sullivan, published in JCI Insight in 2017, found that a single dose of CBD reduced the blood pressure of healthy volunteers. While this is great news if you suffer from high blood pressure, it could be a problem if you happen to have low blood pressure. Therefore, we recommend talking about CBD with your doctor if your blood pressure is on the low side.

Lightheadedness

This side effect is linked to a fall in blood pressure. If this happens to you, try consuming some caffeine as it could help normalize your blood pressure.

There are also reports of a handful of other side effects but in general, they are linked to medical conditions. An example is an increase in tremors among patients with Parkinson’s. However, much more research is needed as we have honestly only scratched the surface of CBD research in general.

Why Choose CBD Instead of THC?

CBD has a different effect from THC because it affects the cannabinoid receptors differently. While THC binds directly to the CB1 receptor, CBD doesn’t directly trigger either the CB1 or CB2 receptors. Instead, it modifies the ability of the receptors to bind to cannabinoids, and influences other types of receptors, while increasing your natural level of cannabinoids through the occupation of specific enzymes.

However, while CBD is not without side effects, they do appear to be less of an issue; at least according to the research to date. Whereas THC can cause more severe side effects such as paranoia and an increase in anxious thoughts.

Final Thoughts About CBD

No one is suggesting that CBD is perfect, nor should they. There is still a LOT of research that needs to be done regarding this popular cannabinoid. At present, we know it won’t intoxicate you like THC, which is one of the reasons why parents feel more comfortable giving CBD, rather than THC, to their children.

Although high-quality CBD isn’t cheap, it could be effective for those unable to afford the ever-rising prices of some prescription medications.

If you decide to use CBD, it is your responsibility to research the cannabinoid to decide whether it is right for you. Also make sure you use it sensibly. And remember, none of the information in this article should be taken as medical advice.

Everything you need to know about CBD oil

CBD may benefit a person’s health in a variety of ways.

Natural pain relief and anti-inflammatory properties

People tend to use prescription or over-the-counter drugs to relieve stiffness and pain, including chronic pain.

Some people believe that CBD offers a more natural alternative.

Authors of a study published in the Journal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats.

The researchers suggested that the non-psychoactive compounds in marijuana, such as CBD, could provide a new treatment for chronic pain.

Quitting smoking and drug withdrawals

Some promising evidence suggests that CBD use may help people to quit smoking.

A pilot study published in Addictive Behaviors found that smokers who used inhalers containing CBD smoked fewer cigarettes than usual and had no further cravings for nicotine.

A similar review, published in Neurotherapeutics found that CBD may be a promising treatment for people with opioid addiction disorders.

The researchers noted that CBD reduced some symptoms associated with substance use disorders. These included anxiety, mood-related symptoms, pain, and insomnia.

More research is necessary, but these findings suggest that CBD may help to prevent or reduce withdrawal symptoms.

Epilepsy

After researching the safety and effectiveness of CBD oil for treating epilepsy, the FDA approved the use of CBD (Epidiolex) as a therapy for two rare conditions characterized by epileptic seizures in 2018.

In the U.S., a doctor can prescribe Epidiolex to treat:

  • Lennox-Gastaut syndrome (LGS), a condition that appears between the ages of 3 and 5 years and involves different kinds of seizures
  • Dravet syndrome (DS), a rare genetic condition that appears in the first year of life and involves frequent, fever-related seizures

The types of seizures that characterize LGS or DS are difficult to control with other types of medication.

The FDA specified that doctors could not prescribe Epidiolex for children younger than 2 years. A physician or pharmacist will determine the right dosage based on body weight.

Other neurological symptoms and disorders

Researchers are studying the effects of CBD on various neuropsychiatric disorders.

Findings suggested that CBD may also treat many complications linked to epilepsy, such as neurodegeneration, neuronal injury, and psychiatric diseases.

Another study, published in Current Pharmaceutical Design, found that CBD may produce effects similar to those of certain antipsychotic drugs, and that the compound may provide a safe and effective treatment for people with schizophrenia. However, further research is necessary.

Fighting cancer

Some researchers have found that CBD may prove to combat cancer.

Authors of a review published in the British Journal of Clinical Pharmacology found evidence that CBD significantly helped to prevent the spread of cancer.

The researchers also noted that the compound tends to suppress the growth of cancer cells and promote their destruction.

They pointed out that CBD has low levels of toxicity. They called for further research into its potential as an accompaniment to standard cancer treatments.

Anxiety disorders

Doctors often advise people with chronic anxiety to avoid cannabis, as THC can trigger or amplify feelings of anxiousness and paranoia.

However, authors of a review from Neurotherapeutics found that CBD may help to reduce anxiety in people with certain related disorders.

According to the review, CBD may reduce anxiety-related behaviors in people with conditions such as:

  • post-traumatic stress disorder
  • general anxiety disorder
  • panic disorder
  • social anxiety disorder
  • obsessive-compulsive disorder

The authors noted that current treatments for these disorders can lead to additional symptoms and side effects, which can cause some people to stop taking them.

No further definitive evidence currently links CBD to adverse effects, and the authors called for further studies of the compound as a treatment for anxiety.

Type 1 diabetes

Type 1 diabetes results from inflammation that occurs when the immune system attacks cells in the pancreas.

Research published in 2016 by Clinical Hemorheology and Microcirculation found that CBD may ease this inflammation in the pancreas. This may be the first step in finding a CBD-based treatment for type 1 diabetes.

A paper presented in the same year in Lisbon, Portugal, suggested that CBD may reduce inflammation and protect against or delay the development of type 1 diabetes.

Acne

Acne treatment is another promising use for CBD. The condition is caused, in part, by inflammation and overworked sebaceous glands in the body.

A 2014 study published by the Journal of Clinical Investigation found that CBD helps to lower the production of sebum that leads to acne, partly because of its anti-inflammatory effect on the body. Sebum is an oily substance, and overproduction can cause acne.

CBD could become a future treatment for acne vulgaris, the most common form of acne.

Alzheimer’s disease

Initial research published in the Journal of Alzheimer’s Disease found that CBD was able to prevent the development of social recognition deficit in participants.

This means that CBD could help people in the early stages of Alzheimer’s to keep the ability to recognize the faces of people that they know.

This is the first evidence that CBD may slow the progression of Alzheimer’s disease.

Additional CBD Oil Benefits

CBD studies are not limited to pain, anxiety, depression, sleep and seizures. Academics and doctors around the world are also currently researching the impact of CBD in:

  • Improving Heart Health—research has found that CBD oil not only reduced blood pressure but somewhat regulated it.
  • Treating Acne—a study found that CBD may be useful in fighting acne, as it prevents not only oily secretions but also possesses anti-inflammatory properties.
  • Helping With Psychotic Symptoms—specifically, those caused by mental disorders.
  • Anti-Tumor Effects—animal studies have been promising in showing CBD’s anti-tumor effects.

It should be made clear right now, there is no evidence that CBD oil benefits those with cancer. People around the world are using CBD oil for its potential benefits; however, research is still in its infancy, and you should not replace any medication you are on. It’s also recommended to speak with your doctor before you begin using CBD oil to see how it can affect you.

If you’re new to CBD and wondering what product is best for you, check out this CBD quiz.

Now that we’ve talked about the benefits, let’s move on to the legality of CBD oil.

Due to its association with marijuana, people get confused about the legality of CBD oil. In 2018, the Agricultural Improvement Act (the Farm Bill) was passed, and this removed hemp from the Controlled Substances Act.

This means that hemp-derived CBD is legal in the U.S.—but under specific certain conditions.

For CBD oil to be legal, CBD should be derived from hemp and contain no more than 0.3% THC. CBD that comes from the marijuana plants remains illegal under the Controlled Substances Act.

Is CBD Oil Legal in My State?

However, at the state level, things get more complicated, and although CBD is legal federally, the laws of some states are not in-line with federal regulations. Although most online e-commerce stores will ship CBD oil to all 50 U.S. states, if you live in Idaho, Nebraska or South Dakota, you are risking the wrath of authorities if you get caught with CBD oil.

Where to Buy CBD Oil?

So now you understand the potential benefits and uses of CBD oil and know that it’s legal. Naturally, the next question on your lips is probably about finding the best CBD product for you, so you’re going to type the following into Google:

Buy CBD Oil Online

Buy CBD Oil Near Me

There are advantages and disadvantages to both, but one thing for sure is that you should not buy CBD oil from Amazon.

A simple search on Amazon brings up over 3,000 searches; however, Amazon does not allow you to buy CBD oil. Amazon prohibits the sale of products containing CBD, so what you see there is actually hemp seed oil, which is extracted by cold-pressing hemp seeds.

Buy CBD Oil Online

Not purchasing from Amazon does not mean that you shouldn’t buy CBD oil online.

We’ll talk more about this later. Still, reputable e-commerce companies always include information about the source of CBD; they’re happy to provide customers with lab results that let them prove the quality of their products.

Buying CBD online also means that you can easily compare the prices between different CBD companies.

CBD Oil Near Me

Depending on where you’re located in the U.S., buying CBD oil from a dispensary might not be the best idea.

Many dispensaries that sell CBD oil are actually illegal, and therefore the brands they stock are on the black market.

Instead of getting high-quality CBD oil, you’re probably buying CBD oil that does not contain the ingredients on the label.

You can buy CBD products in some major retail stores; however, they are much more expensive than what you can find online, and they’re not the highest quality.

There are many e-commerce companies out there that offer fast shipping and good quality CBD oil, so if you’re new to CBD, then do your research and buy from a trusted online store.

How to Buy High-Quality CBD Oil

Price should not be an indicator of the quality of CBD oil.

Profit margins in CBD are huge. In early December, Charlotte’s Web blamed their poor financial results on the fact that they have “seen many companies entering the CBD segment due to a lower barrier of entry and ample supply of hemp raw materials.”

In other words, CBD companies can no longer charge customers ridiculous amounts. CBD oil does not have to be expensive.

A 30 mL tincture, with 500 mg of CBD oil for sale costs between $50-$60, while a 1000 mg, 30mL CBD oil for sale should cost between $80-$100.

The main things you should consider when buying CBD oil are listed below.

1. Lab Results: Does the company you are buying from offer lab results before you purchase?

2. Full-spectrum vs. CBD Isolate: Remember, for CBD oil to be legal in the U.S., it must contain less than 0.3% THC.

  • Full-spectrum CBD contains less than 0.3% THC and lets you experience the entourage effect.
  • The entourage effect lets you experience all the benefits of the other compounds found in the hemp plant. Some people prefer this, for example, those wanting CBD oil for pain.
  • CBD isolate products contain pure CBD. These CBD oils contain zero THC. These are great for people who are new to CBD and want to test it out or those who want absolutely no other compound in their system.

3. CBD Strength: Power users or those looking for stronger effects may prefer CBD oil that is available in 1000 mg and 1500 mg, whereas those new to CBD should go for something lower, for example, a 500 mg product.

4. Extraction Method: You want to make sure that the CBD that you buy is cleaned of any unwanted toxins. The supercritical carbon dioxide extraction method allows this. Any other CBD extraction method will result in inferior quality CBD oil.

So when buying high-quality CBD oil, make sure that you don’t overpay. Expensive does not mean better; however, consider the lab results of the CBD oil company, the type of CBD you need, the CBD strength and the extraction method to create the CBD oil.

How to Take CBD Oil

CBD oil can be consumed in several different ways; here are the most common:

1. CBD Oil Tincture: A form of oral CBD oil ingestion. CBD tinctures are sold in dropper bottles. Simply use the dropper and place one or two drops under your tongue.

2. CBD Gummies: CBD gummies are treats that have been infused with CBD oil and come in tasty flavors. Simply eat a gummy for your dose of CBD.

3. CBD Capsules: CBD oils can be created in the form of a capsule. Ingest it like conventional medicine.

4. CBD Cream: CBD topicals are also called CBD creams; these are infused with CBD, and they penetrate the skin. The best CBD creams are made with “nano-CBD.” This is CBD that is small enough to penetrate the skin and be absorbed by your blood stream for targeted relief.

How Much CBD Oil Should I Take?

The amount of CBD oil that you should take to experience the benefits of CBD oil depends on several factors, the main ones are your weight, and the effects you want to experience. You can use our handy table to work out what the best dose for you to experience CBD oil’s benefits.

Side Effects of CBD Oil

According to the World Health Organization, “to date, there is no evidence of public health-related problems associated with the use of pure CBD.” However, in studies side effects have included:

  1. Tiredness from taking too much;
  2. Changes in weight; and
  3. Interactions with other medicines.

CBD is considered safe, and you should not worry about taking it. However, it’s always best to consult your doctor before you take it to experience CBD oil benefits.

CBD Oil: Is It Right for Me?

Anecdotally, CBD oil benefits are plentiful. People use CBD oil for pain, CBD oil for anxiety, CBD oil for sleep and many other ailments. The benefits of CBD oil have yet to be proven by concrete scientific research, but the existing studies show promise.

Still, with all the purported CBD oil benefits, it’s worth doing your due diligence. If you’re choosing to try it, you can check out a list of recommended products here.

Buying CBD oil online lets you do full research and shop at your own convenience. We also recommend using our helpful guide to find your correct dose, as well as keeping up to date with state and federal legislation to ensure the CBD that you’re using is legal.

For now, CBD that is derived from hemp, contains less than 0.3% THC, grown by licensed producers, and not marketed to have any therapeutic benefits is federally legal.

Remember to buy CBD oil from brands that are trusted. When it’s all said and done, monitor the CBD oil benefits daily, as it affects everyone differently. If you’re new to CBD, then when it comes to dosage, start low and go slow.

What are the health benefits of CBD Oil?

Many manufacturers of CBD Oil (cannabidiol) products claim CBD is effective at relieving anxiety, depression, pain, inflammation, improving sleep, or has other health benefits. A CBD product (Epidolex) has been FDA approved to treat epilepsy.

However, there are very few well-conducted trials to back up these claims, apart from the use of CBD in two rare and severe forms of epilepsy, Lennox-Gastaut syndrome (LGS) and Dravet syndrome. Most trials that have been published have used either marijuana, a combination of CBD and THC (tetrahydrocannabinol), or only involved animals. Very few have been conducted on CBD alone.

Over 200 different substances (called cannabinoids) can be extracted from the Cannabis plant; CBD and THC are just two of these substances. Unlike THC, CBD has no psychoactive properties and will not give you a “high”. There is no evidence it has any abuse or dependence potential and to date there is no evidence that it is associated with any serious side effects, according to the World Health Organization.

The main reason there are few trials to back up the perceived health benefits of CBD is that previous laws lumped marijuana and hemp together in the same basket. However, in December 2015, the FDA eased the regulatory requirements for CBD, which allowed for more research into CBD and trials are now underway investigating its benefits for Parkinson’s disease, schizophrenia, diabetes, multiple sclerosis and anxiety. The government’s position on CBD remains confusing, despite all 50 states legalizing CBD with varying degrees of restriction.

In summary, the only proven health benefit for CBD current is for Lennox-Gastaut syndrome (LGS) and Dravet syndrome (two forms of epilepsy). Other possible health benefits for CBD (these require further investigating) include relieving:

  • Acne
  • Anxiety
  • Arthritis pain
  • Depression
  • Inflammatory pain
  • Muscle-spasticity in multiple sclerosis
  • Nausea and vomiting associated with cancer
  • Nerve-related pain
  • Sleep disorders.

Side effects of CBD may include nausea, tiredness and irritability, and it may interact with some medications, such as warfarin.

Because CBD is currently marketed as a supplement, it is not regulated for safety and purity. Which means you cannot be sure if the product you are buying does contain CBD at the dosage listed, or if it contains any other (unlisted) ingredients. Also, because research into CBD is scarce, nobody really knows the most effective therapeutic dose of CBD for any medical condition.

Even as the knowledge of marijuana’s medicinal value is spreading across the world, more and more states in the US are legalizing its use. And with that, a product called CBD oil is also gaining popularity as a therapeutic drug to naturally cure health issues like anxiety, insomnia, and even cancer.

So, before we explain the benefits of CBD oil in detail, let’s first understand what CBD really is.

Even as the knowledge of marijuana’s medicinal value is spreading across the world, more and more states in the US are legalizing its use. And with that, a product called CBD oil is also gaining popularity as a therapeutic drug to naturally cure health issues like anxiety, insomnia, and even cancer.

So, before we explain the benefits of CBD oil in detail, let’s first understand what CBD really is.

What is CBD Oil & its extraction

CBD or Cannabidiol is one of the 104 chemical compounds, known as cannabinoids, found in the cannabis plant, which belongs to the Cannabis sativa species. CBD is a non-intoxicating component of the plant and is believed to have many therapeutic effects on the human body and mind.

Since CBD is a non-psychoactive component, CBD oil does not cause a “high” or the euphoric sensation that is generally associated with cannabis or marijuana. CBD oil has no or negligible traces of THC (tetrahydrocannabinol – another compound found in the plant), which is indeed a psychoactive cannabinoid and is responsible for the famous marijuana high.

Cannabidiol is extracted from cannabis or hemp (plants, both belonging to the Cannabis Sativa family) and diluted with a carrier oil like coconut oil or hemp seed oil to create CBD oil. Due to controversies surrounding the cannabis plant, industrial-grade CBD is extracted from hemp (another plant that falls under the Cannabis Sativa species), as it has less than 0.3% THC.

Manufacturers sell CBD oils in different forms – tincture, concentrate, soft gel capsules, topical solution, under-the-tongue sprays, wax, edibles, skin creams, and patch. The CBD concentration in each of these products may vary.

Although several studies have exhibited CBD oil’s benefits on patients suffering from epilepsy, anxiety issues, heart problems, Schizophrenia, inflammation, chronic pain, and addiction, research is still on and scientists aren’t entirely certain CBD oil’s exact level of efficiency in treating these ailments.

What are the Benefits of CBD Oil?

Cannabidiol has been proven to be a good remedy for many health conditions. Before we discuss the benefits of CBD oil on the human body and mind in more detail, we must add that the use of CBD oil in any form is quite safe as it does not lead to dependence or tolerance towards the drug. So, it is an excellent choice for those trying to kick addictions or stay away from addictive drugs. So far, CBD oil has been reported to help in:

1. Relief from Chronic Pain & Inflammation

People suffering from chronic pain resulting from fibromyalgia have experienced relief after using CBD oil. Using CBD oil has also been found to offer common pain relief and prevent the degeneration of the nervous system.

In Canada, it has been approved for the treatment of multiple sclerosis and cancer pain. According to the authors of a study, published in the Journal of Experimental Medicine, CBD significantly reduced chronic inflammation and pain in some mice and rats. The researchers suggested that CBD can provide a new treatment for chronic pain.

Chronic inflammation, according to the National Center for Biotechnology Information, leads to many non-infectious diseases like heart disease, cancer, Alzheimer’s Disease, Type 1 Diabetes, and even autoimmune disease. Research shows that CBD can treat inflammation and in turn help alleviate these diseases. In short, CBD helps with pain relief.

2. Calms Epilepsy

CBD has been proven to have anti-seizure properties that can successfully treat children with drug-resistant types of neurological disorders like epilepsy.

In a study published in the New England Journal of Medicine, CBD showed a decrease in the frequency of seizures by 23 percentage points over those taking a placebo.

In fact, in June 2018, the US Food and Drug Administration (FDA) advisors approved the prescription use of Epidiolex, a purified form of CBD oil, for treating two rare and severe forms of epilepsy in patients of the ages of 2 years and older. These two forms of epilepsy – Lennox-Gastaut Syndrome (LGS) and Dravet Syndrome (DS) – generally don’t respond to anti-seizure medications.

Epidiolex happens to be the first FDA-approved drug that contains a purified form of a drug derived from marijuana. This drug reduces the seizures and sometimes stops them altogether. Remarkable visual proof of its effects on children suffering from “childhood epilepsy” is available on the internet for people to view.

On June 25, Dr. Scott Gottlieb, on behalf of the FDA, stated: “Today, the FDA approved a purified form of the drug cannabidiol (CBD)…The new product was approved to treat seizures associated with two rare, severe forms of epilepsy in patients two years of age and older.”

Research has also suggested that CBD can help treat complications arising from epilepsy, like neurodegeneration, neuronal injury, and psychiatric diseases.

3. Anxiety & Depression

According to the Anxiety and Depression Association of America, depression affects 6% and anxiety affects 18% of the population in the US each year. Their research shows that CBD oil can help with both problems.

While doctors generally advise people suffering from chronic anxiety to avoid cannabis, since even traces of THC can trigger or increase anxiety and paranoia, authors of a review published in the journal Neurotherapeutics in 2015 derived that CBD, a non-psychoactive compound, can actually help reduce anxiety in people with certain anxiety-related behavioral disorders, such as:-

  • Post-traumatic stress disorder (PTSD)
  • General anxiety disorder
  • Panic disorder
  • Social anxiety disorder
  • Obsessive-compulsive disorder (OCD)
  • Substance-abuse disorders

However, these conclusions were derived through experimental research, clinical trials, and epidemiological studies, and no human-based research is available at this point.

CBD has been seen to also reduce stress and discomfort associated with public speaking.

With regard to depression, CBD has been seen to reduce depression by enhancing both serotonergic and glutamate cortical signaling (both of which are lacking in people suffering from depression). To read more about CBD oil for anxiety (visit here)

4. Reduce Oxidative Stress

Oxidative stress is a condition when the body has too many free radicals and antioxidants aren’t able to neutralize all of them. This is a comparatively recent problem these days, owing to the rising toxicity in our environment.

Two separate studies have shown that CBD oil has antioxidant and neuroprotective qualities that help in reducing neurological damage caused by free radicals.

5. Aid Treatment of Heart Ailments

Heart disease is also a growing problem across the world. In fact, it’s one of the leading causes of death in the United States. A healthy diet and lifestyle is a top priority for such people, but CBD oil can also help.

In a small study published in JCI Insight in 2017, researchers observed that CBD can help prevent blood-pressure fluctuations due to stress. In this study, nine healthy male volunteers were given a single dose of either CBD or placebo. Those treated with CBD had lower blood pressure, compared to those given a placebo, both before and after experiencing a stressful event.

According to researchers, cannabidiol helps by:

  • Reducing artery blockage
  • Reducing stress-induced cardiovascular response
  • Reducing blood pressure
  • Reducing cholesterol level

CBD oil helps prevent oxidative stress and inflammation, both of which are often precursors to heart diseases.

6. Fights Multi-Drug Resistant Bacteria

According to many experts, cannabinoids (including CBD) have an unusual ability to destroy bacteria (especially the drug-resistant strains). While more research is still needed to understand how and why it works, according to a 2011 study, CBD can slow down the progression of tuberculosis in rats. Researchers concluded that CBD likely does this by inhibiting T-cell proliferation, rather than possessing antibacterial properties.

Whatever may be the mechanism for destroying bacteria, CBD certainly seems to be a potent weapon against the newly emerging antibiotic-resistant “superbugs”.

7. Treat Type 1 Diabetes

We have already discussed how CBD oil helps combat inflammation. The same is true for when the immune system attacks the pancreatic cells, causing Type 1 Diabetes.

Research published in 2016 by Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, found that CBD may ease this inflammation in the pancreas.

Similarly, a paper presented the same year in Lisbon, Portugal, suggested that CBD can reduce the inflammation and protect against or even delay the development of Type 1 Diabetes.

8. Help with treating Schizophrenia

Schizophrenia is a serious and complicated mental illness that is typically managed through therapy and pharmaceutical drugs (that often have severe side effects). Whereas, many people have found CBD oil helpful in reducing hallucinations, minus the side effects.

According to the March 2015 review of research, CBD is a safe, effective, and well-tolerated treatment for psychosis. But more research is needed to bring CBD into clinical practice.

You must remember that THC, a psychoactive compound found in marijuana, can, in fact, increase psychosis among the affected individuals, while CBD only helps reduce it and may even counteract psychosis brought on by marijuana abuse.

Yet another study, published in Current Pharmaceutical Design, another peer-reviewed medical journal that covers issues related to pharmacology and medicinal chemistry, found that CBD has effects similar to those of certain antipsychotic drugs and that this compound is much safer and a more effective option for people with schizophrenia.

9. Treat skin conditions

Several studies have shown that CBD oil has a high potential for treating skin conditions, like eczema, by encouraging abnormal cell death.

It also helps regulate the skin’s oil production, thus reducing acne. A 2014 study reported by the Journal of Clinical Investigation, a biomedical journal published by the American Society for Clinical Investigation, found that CBD helps to lower the production of sebum, partly because of CBD’s anti-inflammatory property. Owing to these reasons, CBD could well become the future treatment for acne vulgaris, the most common form of acne.

It will be interesting to note that cannabidiol also contains certain nutrients like vitamin E that help nourish and protect the skin.

10. Fight addiction

CBD oil may help people with addiction overcome their withdrawal symptoms, suggested a review published in the journal Substance Abuse in 2015. In their report, they analyzed 14 previously published studies in which scientists determined that CBD may have a therapeutic effect on people with opioid, cocaine, and/or psycho-stimulant addiction.

They also found that CBD may help treat those with cannabis and tobacco addiction. Researchers have found evidence of CBD blocking or sometimes reducing THC’s effect on the mind.

A pilot study, published in Addictive Behaviors, found that smokers, who used inhalers containing CBD, smoked fewer cigarettes than usual. They also did not suffer from any withdrawal symptoms like cravings for nicotine.

A similar review, published in Neurotherapeutics, noted that CBD reduces symptoms associated with substance abuse, such as anxiety, mood-related symptoms, pain, and insomnia.

More research is necessary, but these findings definitely point to the possibility of CBD helping prevent or reduce withdrawal symptoms.

11. Fight certain types of Cancer

For people fighting cancer, CBD may provide them with a natural alternative for pain and symptom relief.

Although more research needs to be done on CBD’s role in treating cancer, whatever data is currently available looks promising.

According to the American Cancer Society, CBD oil can slow down the growth and spread of certain types of cancer (in animals), given that this psychoactive compound efficiently fights oxidative stress and inflammation.

According to a review published in the British Journal of Clinical Pharmacology, CBD can significantly help prevent the spread of cancer. The researchers noted that the compound tends to suppress the growth of cancer cells and promote their destruction.

12. Alzheimer’s Disease

CBD can prevent the development of social recognition deficit among patients, suggested research published in the Journal of Alzheimer’s Disease. This means that CBD could help people in the early stages of Alzheimer’s retain their ability to recognize faces they know, and in turn slow the progression of the disease.

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Is CBD oil useful for everyone? Who can benefit from it?

As per a recent report by the World Health Organization, CBD products are usually safe for everyone. However, if you are pregnant, it may have a negative impact on your body and that of your unborn child. Besides, if you are currently on any medication, you must consult a doctor before you use CBD oil. This is to ensure that there are no negative fall-outs from mixing the two.

CBD oils have been seen to have positive effects on both humans and animals.

On humans, they can help improve or treat a wide range of health issues, from everyday ailments to some chronic conditions. CBD’s health benefits include:

  • Acne
  • Anxiety
  • Depression
  • Chronic pain
  • Inflammation
  • Insomnia
  • Epilepsy
  • Glaucoma
  • Type 1 Diabetes
  • Loss of appetite and body weight
  • Parkinson’s disease
  • Alzheimer’s disease
  • Heart ailments
  • Some forms of cancer

It has also been found that CBD helps some animals overcome similar health issues, owing to the fact that all mammals have an endocannabinoid system.

Particularly for cats and dogs that we humans prefer to keep as pets, CBD oil may help with:

  • Excessive barking or crying
  • Pets getting along with other pets
  • Alleviating Pain
  • Relaxing pets before a trip to the vet or long travel
  • Lack of appetite
  • Separation anxiety

With pets, it is difficult to gauge the exact dosage. But a dose of 1 mg per 10 pounds of body weight is a good place to start. You increase the dose to up to 5 mg for the same bodyweight if need be. A higher dose may be necessary in certain cases. However, it is best to consult a vet before increasing the dosage. Repeat the dose 3-4 times a day for a better impact.

How does CBD oil really work?

To take effect, cannabinoids like CBD attach to certain receptors in the body’s endocannabinoid system(ECS), which is a complex biological system responsible for regulating certain specific aspects of bodily functions, like memory, sleep, and mood, as well as metabolic processes like energy balance.

CBD oils are also believed to improve several other kinds of health conditions. According to recent research, all these health issues are caused by the deregulation of the ECS.

Interestingly, the endocannabinoid system, something most people wouldn’t have heard about until recently, was discovered through various research and studies on the effects of cannabis on the body and was hence named after the plant itself.

The ECS made up of endocannabinoids and their receptors are spread across the entire body, from the brain and other organs to glands and immune cells. This system throws up a varied kind of reactions in different parts of the body. However, it is all about homeostasis or internal balance. The receptors in the brain control coordination and movement, pain, emotions, and mood, thinking, appetite, and memories, among other functions, while those found in the immune system affect pain and inflammation.

The exhilarated feeling of euphoria after a long run or after intercourse is caused by endocannabinoids that get stimulated by these natural acts to make you feel “high” – an elated feeling with hardly any or no pain.

CBD and THC act as external stimulants that have similar effects on this very powerful body system, causing different kinds of reactions on different parts of the body.

How long does it take for CBD to take effect?

Most people use CBD oil by ingesting it with the help of a dripper. Given that its use is comparatively new, its exact dosage isn’t established yet. Hence, an exact time frame for its effect to kick in is also difficult to determine. It has been seen that different people react to CBD at different rates and in different ways.

Although more extensive research is needed in this area, no case of CBD overdose has been reported so far. Also, there are very few, if any, side effects, making overdosing almost impossible.

Most companies will provide you with an estimated dosage on the instruction label/manual. If you are taking it as a preventive supplement or a cure, stick to those instructions.

Some may see a noticeable change within seconds, while others may not notice anything for weeks. If you are taking it for inflammation or pain, for instance, and you don’t see improvement for weeks, you may want to increase the dosage, but of course in consultation with a doctor.

It is believed that a small dose of CBD 3-4 times a day has more therapeutic benefits than one large dose.

However, one must remember that CBD oil, though quite safe on its own, may react with other medications, particularly steroids and opioids. So, always consult a doctor before trying such alternative methods of treatment.

Are there any side effects?

Everything we eat or drink to prevent or manage health issues may carry some risk of side effects. Hemp oil is no exception to that rule. However, no cases of toxicity from the use of hemp-based BD oil have been reported so far. It has hardly any negative impact on humans and may occur only in rare cases and that too in a mild way.

According to some researchers, the use of CBD oil may trigger several side effects, although mild, such as:

  • Changes in appetite
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Nausea
  • Anxiety
  • Bloating
  • Vomiting

All of the above symptoms are generally mild and dose-dependent and tend to resolve within 2 to 4 hours. But, it is best to consult a doctor if any of these symptoms are noticed.

Cannabidiol is comparatively safe when consumed in appropriate doses among adults. (*)

  • CBD doses of up to 300 mg daily have been used safely for up to 6 months.
  • Doses of 1200-1500 mg daily have been used safely for up to 4 weeks.
  • Cannabidiol under-the-tongue sprays have been used in doses of 2.5 mg for up to 2 weeks.

Safety concerns: Cannabidiol tends to react with certain medications, particularly opioids and certain types of anti-epileptic drugs.

In a study, children with refractory epilepsy, treated with CBD, experienced aggravated seizures, sleepiness, digestive troubles, and irritability.

A report from the American Academy of Pediatrics (AAP), published in the journal Pediatrics, urges pregnant women and nursing mothers to avoid marijuana use due to possible adverse effects on their baby. According to a study mentioned in the report, short-term exposure to CBD was found to increase the permeability of the placental barrier, potentially exposing the fetus to risk from certain substances.

The question of legality

CBD derived from industrial hemp is legal across the US as a therapeutic drug, while the same compound derived from cannabis or marijuana is now legal only in 46 states, that too with a prescription.

The four states where cannabis-derived CBD is completely illegal are Idaho, Kansas, Nebraska and South Dakota.

At the federal level in the US, CBD is classified as a Schedule 1 drug, because it is one of the many cannabinoids present in cannabis. However, all CBD products derived from industrial hemp are being sold legally, but only under strict regulations of the 2018 Farm Bill that states that legal hemp-derived CBD products must contain less than 0.3% THC and can only come from licensed hemp growers.

While most states require a prescription, the prescription needed for use and possession varies from state to state. For instance, in Missouri, a person can use CBD of a particular composition if they can show that three other treatment options have failed to treat their epilepsy.

So, the legality of CBD can be a bit tricky and the laws relating to this compound keep changing.

The last word

Research on the potential health benefits of CBD oil is still on. So, we can expect to discover many more therapeutic uses for this natural compound in the near future.

Although CBD’s efficacy and safety are still not crystal clear, recent studies suggest that this compound may provide a safe, powerful natural remedy for many health issues in the coming days.

Cannabidiol (more commonly known as CBD) has experienced a surge in popularity in recent months, in part due to its availability in high-street health shops.

Previously viewed as an option only for the seriously ill, CBD oil is gaining traction among wellness fans – but why?

‘The media has no doubt helped drive this popularity,’ says Dr Sarah Brewer, medical director at Healthspan. ‘However, the main drive is because people who take it experience the benefits very quickly, and “word of mouth” is a powerful thing. CBD oil also has such a wide range of benefits, reducing anxiety, promoting relaxation, ensuring a good night’s sleep, reducing pain perception and improving general feelings of wellbeing. It therefore appeals to a wide range of people.’

But what exactly is CBD oil – and are there any associated risks?

Is CBD the same as cannabis?

CBD is one of 104 chemical compounds, known as cannabinoids, that can be found in the cannabis plant. It’s a naturally occurring substance, which can be extracted and mixed with a carrier oil – often hemp seed or coconut – to create CBD oil.

Unlike the most well-known cannabinoid, tetrahydrocannabidiol (THC), CBD is not psychoactive, meaning that it won’t make you ‘high’ – the sensation most commonly associated with cannabis. It is, however, reported to offer a range of health and medicinal benefits – the reason behind its growing acclaim.

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Is CBD oil legal?

There has been a fair amount of confusion surrounding the legality of CBD oil. But while the vast majority of cannabinoids are controlled substances under the Misuse of Drugs Act, rest assured that CBD oil is legal across the UK for medicinal purposes, provided it has been derived from an industrial hemp strain that is EU-approved. These strains contain very little to no THC (the psychoactive cannabinoid).

There are strict restrictions in place with regard to CBD oil’s THC content: for CBD oil to be legal in the UK, it must contain no more than 0.2 per cent THC, and the THC must not be easily separated from it.

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How do you take CBD oil?

CBD oil is most readily available as a tincture. This can be taken by applying a few drops under your tongue, holding in your mouth for a few moments so it can be absorbed, before swallowing. It can also be added to water or smoothies. A spray form is available (simply spritz under your tongue), as are capsules, gummies, creams that can be applied topically, and e-liquid for vape pens.

When it comes to dosage, guidelines state you should start with the smallest possible dose – its effects should be immediate, so you will be able to tell if the lower dosage is working for you. However, it’s always best to consult your doctor before trialling any new medication or remedy.

CBD can be taken by applying a few drops under your tongue, and holding in your mouth.

‘I recommend starting with a low dose and slowly building up over a few weeks, to find the dose that works best for you,’ agrees Dr Brewer. ‘For example, start with Healthspan High Strength CBD Oil 6.4mg Capsules, taking one to three daily. Then, if needed, move up to Super Strength CBD 15mg Capsules, taking one to two daily. CBD is not psychoactive and is not addictive. I prefer capsules, as CBD drops have a strong taste, although filter-clear peppermint flavoured drops are available.’

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What are the benefits of CBD oil?

While the majority of research done into the effects of CBD oil has been based on animal studies and anecdotal evidence, some pretty clear benefits have been highlighted:

CBD oil can alleviate pain

Many studies – both animal and human – have examined the link between CBD and pain relief, which are thought to be down to the oil’s ability to reduce inflammation and interact with neurotransmitters.

‘CBD has been described as a multi-target molecule,’ expands Dr Brewer. ‘It is highly antioxidant, so has anti-inflammatory effects on joints, to improve pain and stiffness. CBD also has an analgesic effect, to reduce pain perception in the brain.’

As well as pain relieve, CBD oil has been shown to offer benefits to those receiving treatment for cancer.

‘High CBD-content medicinal cannabis products can help reduce nausea, poor appetite, pain and sleep disturbance in cancer patients, as shown in multiple studies,’ says Dr Dani Gordon.

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CBD oil can ease anxiety

Several studies have found that the use of CBD oil is helpful in reducing anxiety, meaning it could be a beneficial natural remedy for sufferers.

‘Cannabidiol interacts with the body’s own endocannabinoid system, enhancing the effects of other brain chemicals to promote relaxation and reduce anxiety, stress, restlessness and fatigue,’ explains Dr Brewer.

Back in 2011, a study published in the journal Neuropsychopharmacology found that when people with generalised social anxiety disorder (SAD) were given 600mg of CBD oil prior to a public speaking test, as opposed to a placebo, they experienced significantly less anxiety, difficulty and discomfort during their speech.

CBD oil is a natural antidepressant

Many studies have examined CBD oil’s antidepressant-like effects. It’s also been shown to safely improve the symptoms of post-traumatic stress disorder (PTSD) in children.

‘CBD has proven anti-anxiety effects and may be helpful in depression, based on anecdotal reports,’ says Dr Gordon. ‘I use high CBD prescription cannabis medicine products as part of a mental health protocol with my patients suffering with anxiety and depression. The antidepressant effects of CBD have been shown in animal models, but we now need large, depression-specific studies in humans as the next step.’

CBD oil could be beneficial in epilepsy treatment

Clinical trials have found CBD to be highly effective in the treatment of certain types of epilepsy. There is also growing evidence to suggest it could help more types, although further research is needed to fully understand safe and optimal dosing.

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Can CBD oil treat acne?

Due to the effects of CBD oil on the immune system and its ability to help reduce inflammation, it may offer relief from acne.

‘Both CBD and THC have been shown in multiple in vitro studies to have anti-acne and topical anti-inflammatory properties,’ reveals Dr Gordon.

In fact, a study published in the Journal of Clinical Investigation found that CBD oil inhibited the production of sebum in the sebaceous glands in the skin.

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Does CBD oil have any health risks?

The majority of CBD oil users don’t experience any negative effects.

‘In doses used as a food supplement, CBD poses few risks, and side effects are unusual but can include a dry mouth or drowsiness,’ reveals Dr Brewer. ‘Higher doses used medically are well tolerated, and there are no serious safety concerns. A World Health Organization report issued in 2017 concluded that cannabidiol does not appear to have abuse potential or cause harm.’

However, CBD oil could interact with common prescription medications, so it’s important you always seek the advice of your GP before giving it a go.

‘If you have a health condition, or are taking any prescribed or over-the-counter medicines, always check with your doctor or a pharmacist for possible drug supplement interactions before taking CBD,’ says Dr Brewer. ‘This is because CBD interacts with enzymes involved in metabolising some medicines and may result in increased drug levels that could cause side effects.

The majority of CBD oil users don’t experience any negative effects.

‘If the Patient Information Leaflet that comes with your medication says to avoid grapefruit juice, for instance, then do not take CBD, as the same type of interaction can affect circulating blood levels of your medicine. Even if the leaflet does not mention grapefruit juice, you should still check with your doctor before taking CBD. You should also not take CBD if you are pregnant or breastfeeding.’

If your doctor is unable to help, Dr Brewer recommends visiting Drugs.com, and using the Drug Interactions checker.

Related Story Claire Chamberlain Contributor Claire is a freelance writer specialising in health, fitness and wellbeing.

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