Weight loss supplements for heart patients

One obesity expert said the finding could boost use of the medication.

“There was concern that certain weight-loss medications were not safe in patients at risk for heart disease,” said Dr. Mitchell Roslin, chief of obesity surgery at Lenox Hill Hospital in New York City.

“Belviq is in the same class of drugs,” noted Roslin, who wasn’t involved in the new trial. “To gain acceptance, the drug would need to show that the same result would not occur. This study shows that there is no increase in cardiac complications with Belviq.”

Bohula’s team published their findings Sunday in the New England Journal of Medicine, and the report was simultaneously presented at the European Society of Cardiology’s annual meeting, in Munich.

The new trial was funded by Belviq’s maker, the pharmaceutical company Eisai.

The study included 12,000 overweight or obese patients at risk for serious heart problems who took either Belviq or a “dummy” placebo pill. Over a median follow-up of more than three years, the research showed no statistical difference in the rate of major heart problems between patients who took Belviq (6.1 percent) and those who took the placebo (6.2 percent).

Along with counseling in better diet and exercise, patients who took Belviq lost an average of 9.3 pounds after one year, while those in the placebo group lost an average of 3 pounds.

Slimming Pills

Slimming pills are not surprisingly a very well-known product in the health supplements market.

From prescription diet pills to the OTC options, many overweight individuals search to find a magic pill that will help them lose weight successfully.

The producers of these pills make over the top claims about the ingredients of their products, but most of these claims are not supported by scientific research.

Theses stimulants that assure to help you get rid of those unwanted fats may have unseen risks to your health. Despite the risks of using slimming pills and fat burners, the interest and sale for these continue to grow, especially among people with eating problems.

According to Eating Behaviors, about 50% of the people who have eating disorders use OTC slimming supplements, herbal pills, fat burners, appetite suppressants, or prescription drugs to shed pounds.

Unless you are taking weight loss products for health reasons under the supervision of a doctor, you may be risking yourself by using these drugs.

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Burniva – The Most Effective Fat Burner

Burniva contains high quality Green Tea extract, Citrus Aurantium and Caffeine Anhydrous which will help you achieve the best result for your weight loss targets.

What Are Slimming Pills?

Slimming supplement is any product that you consume that contributes to the nutrients of your usual diet. Not all products are for losing weight, a pill may add an essential dietary replacement for individuals who are lacking a specific ingredient in their meals.

A diet supplement may contain the following:

• Amino acids

• Vitamins

• Enzymes

• Minerals

• Glandular extracts

• Botanical herbs/products

• Organ products

Individuals consume weight loss supplements and products for various reasons such as to gain back lost nutrients, appetite suppressants, boost energy, improve sleep, create muscle tissue and help with physical functions like vision, lose or gain weight.

Just because a slimming or diet pill is marketed online or at a local pharmacy in very attractive packaging that doesn’t mean it’s effective and safe.

Many individuals aren’t informed that products sold as diet, fat burners, metabolism booster or slimming supplements are not subject to approval by the U.S. FDA unless the pill includes a new element.

It’s, in fact, the responsibility of the manufacturer to prove that the pill is safe, based on the Dietary Supplement and Health Education Act of 1994.

However, not all producers fulfill this order. Many producers have been charged with making false promises about their supplements adding medicinal ingredients to their pills or making their drugs under risky circumstances.

How Are Slimming Pills Abused?

When someone has an eating disorder, she/he may not be concerned of the dangers of slimming pills as they may be more focused of losing weight that they don’t mind the dangers to their health. In a fanatical drive to shed pounds, an individual with bulimia or anorexia will abuse diet or slimming products in the following ways:

• Taking prescription slimming capsule without a doctor’s supervision

• Taking diet products that aren’t endorsed for consumers who are underweight or at a normal weight

• Taking more than the recommended dosage of weight loss supplement or appetite suppressant

• Mixing slimming pills with diuretics or laxatives

• Taking multiple weight loss stimulants and metabolism booster

• Taking weight loss product with illegal drugs or other controlled substance like cocaine or meth

Consuming an extreme amount of slimming supplements or mixing products can be very dangerous.

Overdose of drug products could a consumer at risk of heart attack or stroke be because it could raise the blood pressure to a critically high level.

Taking fat-blocking pills or thermogenic fat burner along with diuretics or laxatives could cause health risks like fluid loss, diarrhea and electrolyte imbalance. Abusing drugs that hold a health risk for kidney damage or liver only increases the likelihood of serious organ failure.

Burniva – Weight Loss

Boost Fat Burning

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How Do Slimming Supplements Work?

You will have no problem of finding dietary or slimming supplements for losing weight since the market is overflowing of the brands, the choice is yours! Manufacturers that issue these drugs claim that the elements in their products can help you get the desired result like these:

• Faster metabolism (B-complex vitamins, guarana, caffeine, synephrine,)

• Appetite suppressants restrict your hunger for food (fennel, bee pollen, chickweed)

• Make you always full before you have had to eat (psyllium, guar gum)

• Prevent your body from consuming the fat in the foods you eat (chondritin)

• Decreases the fat production of your body (flax seed, hydrocitric, green tea)

Slimming supplements are readily available in any form that you can orally take, from pills, capsules to liquids, teas, and powders. Some are consumed with food, while others are as a substitute for your meal.

OTC diet supplements believably help you get rid of excess pounds by stimulating your digestion, the responsibility for using energy.

Caffeine is the main ingredients of most of these weight loss supplements, thermogenic fat burners, appetite suppressants and metabolism booster. It is a central nervous stimulant that may aid eliminate excess fat through thermogenesis. Still, the perils of consuming these drugs may dwarf the benefits.

The following are the most prevalent ingredients in slimming pills and the side effects they carry:

Orlistat

According to Medline Plus, a popular ingredient in diet supplements prescribed to help heavy individuals with heart disease, high blood pressure, diabetes, and high cholesterol is Orlistat. This generally recommended in addition to exercise and low diet, this element blocks some of the fats from the foods you eat being consumed by the intestines. Based on Medline, bowel movements are the most common health problems once can suffer from orlistat. Individuals experience side effects such as trouble of controlling bowel movements, anxiety, headache, irregular menses and flatulence with oily spotting. Severe side effects are excessive weakness, severe stomach pain, difficulty in breathing and vomiting.

Phentermine

Phentermine is the main ingredient responsible for curbing appetite. This diet pill may become habit-forming since it is usually prescribed for three to six weeks only. This comes in extended-release tablets and capsules that should be consumed with meals, according to Medline Plus. Users are warned that phentermine may cause common side effects like constipation, dry mouth, and diarrhea. More detrimental effects known to occur can lead to health risks like heart palpitations, increased blood pressure, dizziness, tremors, and ankle swelling. Medline Plus encourages individuals consuming phentermine to seek the assistance of doctor and laboratory appointments in order to keep track of the response to the product.

Sibutramine

According to PubMed Health, a National Institutes of Health website, Sibutramine is the main ingredient in slimming pills used for losing weight and upkeep of weight loss goals. However, this stimulant does not work for everybody and should be consumed with a reduced-calorie diet and regular exercise. The health website warns sibutramine users that this can be addicting, and the consumer must exactly follow the orders of a doctor. Taking Sibutramine can result in health problems, with common side effects including painful menstrual periods, back pain, runny nose, and constipation. More serious side effects according to PubMed Health are fainting, seizures, excessive sweating, unusual bleeding, fever, swelling of the throat, difficulty speaking and confusion

Why Are Weight Loss Pill and Supplements Dangerous?

Many weight loss and diet pills are nontoxic, and some may even be efficient at boosting the metabolism, burning fat and creating a sense of fullness. But some of the popular main ingredients in dietary products have been banned by the Food and Drug Administration (FDA) because of the dangerous side effects such as:

• Sleeplessness

• Rectal bleeding

• High pressure of the blood

• Increased heart rate

• Kidney problems

• Agitation

• Liver damage

• Diarrhea

These weight loss supplements help you lose weight in many ways such as constraining the digestion of fats and curbing your appetite. Losing weight with slimming and dietary supplements, without the essential lifestyle changes to keep the weight off, can result in regaining all weight back.

Boost Fat Burning

Stimulates More Energy

Combats Craving

Accelerates Metabolism

Helps Focus & Alertness

Burniva contains Green Tea Extract, Citrus Aurantium (Synephrine) and Caffeine Anhydrous, formulated in the right dosage and ratio to provide a powerful and effective synergistic effect. This formula is backed by scientific research and has been proven to enhance fat burning, reduce appetite and boost mental and physical energy. When taken before workouts Burniva will help you perform more intense and longer workouts. Burniva proven formula, combined with an adequate meal plan, can help you reach your weight loss goals faster.

Recommended Intake

As a dietary supplement, take 1 tablet in the morning and 1 tablet in mid-afternoon with 250ml of water.

Burniva is not a medical product and should not replace a well balanced diet and healthy lifestyle. Not for use by individuals under 18 years of age. Do not use if pregnant or nursing. Consult a physician or licensed qualified health care professional before using this product if you have a family history of heart disease, thyroid disease, diabetes, high blood pressure, depression or other psychiatric conditions, glaucoma, difficulty in urinating, prostate enlargement and seizure disorder. Discontinue use or consult a doctor if adverse reactions occur.

Caution This product contains caffeine and should not be used by those willing to eliminate caffeine from their diet. Keep out of reach of children. Store in a cool, dry place away from moisture and direct sunlight.

Using phentermine for weight loss more than 3 months seems safe and effective

Dr. David Arterburn discusses reassuring news from his PCORnet study of a common anti-obesity drug.

KP Washington Health Research InstituteFollow Mar 22, 2019 · 1 min read

By David Arterburn, MD, MPH, a senior investigator at Kaiser Permanente Washington Health Research Institute

Phentermine is the most commonly used anti-obesity medication in the United States. Back when it was approved for weight loss in 1959, the chronic nature of obesity wasn’t understood as well. The U.S. Food and Drug Administration limited treatment to 12 weeks or less. By contrast, when the FDA approved a new brand-named combination medication, Phentermine/Topiramate-CR (Qsymia), in 2012, it was for long-term use for a year or more.

Many doctors prescribe phentermine, on its own, to patients for more than 12 weeks. But there’s a lack of research on its longer-term safety and efficacy. It is available as an inexpensive generic medication, but concerns have been raised about addiction and cardiovascular side effects.

In our study, “Safety and Effectiveness of Longer-Term Phentermine Use: Clinical Outcomes from an Electronic Health Record Cohort,” published in Obesity, my colleagues and I found evidence of better weight loss with longer-term use of phentermine — up to two years’ follow-up. And we didn’t find any link between longer-term use and risk of cardiovascular disease or death up to three years from starting phentermine.

To read Dr. Arterburn’s complete blog post about phentermine, with additional detail about the findings, please visit this web page on the Kaiser Permanente Washington Health Research Institute website: https://bit.ly/2MejpNl

New Science Behind Phentermine

Phentermine is recommended for long term use to lose weight and to maintain weight loss

Note: Much of this material and recommendations are derived from a report by the American Society of Bariatric Physicians TM, entitled “Overweight and Obesity Evaluation and Management.”

Weight loss maintenance

Although phentermine has been used for more than fifty years as a weight loss aide, only recently has its benefits for long-term maintenance been recognized. Appetite suppressants act primarily by lowering the body’s weight set point and only secondarily by suppressing appetite.

As one author noted: “There are strong positive indications for the long term use of appetite suppressants.” Another noted: “The major promise of pharmacotherapy lies not in its ability to improve the amount of weight loss, but in its potential to enhance longer-term maintenance of weight loss with conventional therapies.”

Even small amounts of excess fat can affect your health. There has been a failure to recognize that adverse metabolic conditions may develop with even small amounts of fat gain or abnormalities in fat cell function. Further, the positive psychological effect of weight loss and maintenance as an additional benefit of anorectic usage is often overlooked or ignored.

*Overweight, over-fat, and obesity are variations of a recurrent life-long disease that carries a high risk of diabetes, pre-diabetes, metabolic syndrome, cardiovascular disease and ultimately a risk of premature death and debility if left untreated. Overweight and obesity in the U.S. have increased by more than 75 percent in the past three decades.

Furthermore, “obesity is a chronic relapsing disease for which there is no foolproof cure. Therefore pharmacological therapy should be viewed as a useful adjunct to lifestyle modification.”

Phentermine is Safe

*“Anorectic medications (appetite suppressants) have one of the lowest drug misuse/abuse rates per 100,000 emergency room visits — even lower than Ibuprofen.”

“… as far as the perceived potential addictive properties of phentermine, in 49 years of world-wide use, there has never been a case of addiction reported in the peer-reviewed medical literature.” (PubMed search 6/17/2008)

Phentermine has been proven to be a safe, cost effective and highly successful medication in the treatment of overweight and obese patients. Unfortunately, many of the current guidelines for prescribing it reflect recommendations that are more than 50 years old rather than current evidence of efficacy and safety. There has been an unrealistic and unjustified fear that phentermine is a highly addictive medication.

The Drug Abuse Warning Report of 2006 (DAWN) illustrates that anorectic medications have one of the lowest drug misuse/abuse rates per 100,000 emergency room visits — even lower than Ibuprofen.

DAWN REPORT 2006

Drug # of visits Rate/100,000

Is overeating the problem? Maybe not. The Human and Nutritional Evaluation Survey I (HANES I) surveyed, among other things, the eating habits of 20,749 individuals across the U.S., and found that the obese actually ate less than their normal-weight counterparts. To lose weight and to maintain a reduced weight by means of caloric restriction, these individuals must reduce their food intake even further in relation to energy expenditure. To reach and maintain a normal weight, many obese people are forced to live with chronic hunger. Enduring this level of discomfort on a long-term basis is often more than the patient can bear and the weight is regained.

For many patients, the physician’s advice that eating less will cure obesity is about as helpful as telling hypertensive patients that relaxing will take care of their problem. Without additional help, change usually does not happen. Over the past several decades obesity has moved from being considered a problem of gluttony to that of being an illness or a disease.

Long-term lifestyle changes are necessary for long term success. Medical treatment for weight loss and maintenance includes advice and recommendations for dietary management, behavioral modification, counseling, exercise and appropriate use of medications when indicated, as part of a long-term weight control maintenance program (“weight control” refers to
managing excess adipose tissue).

Pharmacologic Therapy in Overweight and Obesity
“Evidence Based Standard of Care”

Position Statement: Obesity management should be treated similarly to Attention Deficit Disorder (ADD) in which schedule II controlled substances are frequently prescribed yet no special or detailed rules exist. Similarly, we believe that no specific rules are necessary for treatment of overweight or obesity with the much safer schedule III or IV anorectic medications.

Years of experience and additional research have shown these medications to be both effective and considerably safer than was recognized when the scheduling of anorectic medications was initially instituted.

National Institution of Health: “Since obesity is a chronic disorder, the short-term use of drugs is not helpful. The health professional should include drugs only in the context of a long-term treatment strategy.”

Furthermore, “in some cases, weight loss therapeutic agents may even affect metabolic parameters and adipocyte function independently of weight loss alone, suggesting that the benefit of these agents in improving EFRMD may go beyond their efficacy in weight reduction.” (Reference: Expert Rev. Cardiovasc. Ther. 4(6), 871–895 (2006).

This modern approach to the treatment of obesity incorporates medical intervention, dietary, behavioral, and pharmacologic (when indicated) treatments at an earlier stage of the disease and continues therapy for a longer duration of time.

NOTE: Use of BMI understates obesity, particularly in women.

Benefits of weight loss

Weight loss leads to improvement of sleep apnea, diabetes, arthritis pain, improvement of lipids, reduced cardiovascular risk and an increased life expectancy. Also, it may be reasonable to continue some medication for a longer time in selected patients to assure maintenance of weight loss.

It is self-evident that putting time limits on use of medications used in treating a chronic illness is inappropriate when the risk of taking the medication is less than the risk of leaving the illness untreated. In the case of chronic diseases, the FDA does not dictate how long a physician can use insulin in a diabetic, an antihistamine in a patient with allergies, an anti-hypertensive in a patient with hypertension, or a benzodiazepine in a patient with anxiety, etc.

Based on a national survey of ASBP membership, physicians report that anorectic medications are one of the more effective tools available to the clinician. In another recently published study these medications were noted to be safe and effective over the long term.

*Studies exist in the medical literature that support longer-term use of phentermine than the treatment recommended in the PDR. One such study suggests “Long-term pharmacotherapy when combined with appropriate behavioral approaches to improve diet and increase physical activity, helps some obese patients lose weight and maintain weight loss for at least a year.

In another study, 12 patients were treated safely for more than 10 years of continuous use with phentermine. There was no abuse noted. Even the NIH states that as long as medicine is working, there is no time line on how long one should prescribe it.

For some patients stopping or at least slowing age related weight gain may in and of itself constitute a clinical response

Barriers to Appropriate Use

Currently, there are certain barriers to the appropriate use of anorectic medications. These include the following:

  • The perception by the public and some medical professionals that obesity is caused by lack of willpower.
  • Anorectic medications are held to a higher standard in defining desired outcomes than are other medicines.
  • The Schedule III and IV anorectics have a tarnished reputation because of their structural relationship to amphetamines and because of inappropriate prescribing by ill-trained or inexperienced physicians using the medications without a comprehensive program.
  • There is an inappropriate fear of the “dangers” of anorectics and their potential for abuse by patients.
  • Outdated information and rigid adherence to PDR labeling prevent appropriate “off-label” use of anorectics.
  • Many physicians, because of a lack of treatment guidelines and the existence of outdated and/or antiquated federal and or state laws, fear regulatory retaliation if they prescribe anorectic medications.
  • There has been a failure to recognize that adverse metabolic conditions may develop with even small amounts of fat gain or abnormalities in fat cell function.
  • The positive psychological effect of weight loss and maintenance as an additional benefit of anorectic usage is often overlooked or ignored.
  • Barrier: Anorectic medications are held to a higher standard in defining desired outcome than are other medications.
  • Barrier: The positive psychological effect of weight loss and maintenance as an additional benefit of anorectic usage is often overlooked or ignored.

The myth of tolerance seems to have prevented use of appetite suppressants in precisely those situations in which they are indicated which is over the long term. “There are strong positive indications for the long term use of appetite suppressants. Many overweight hypertensive and diabetic patients can control their conditions by weight loss.

Unfortunately, however, many of them cannot lose weight by diet alone (as is true of many of us). As a result, they are forced to rely on long term use of medication to control their hypertension, diabetes, and other conditions. If these patients must receive long-term medication, they may well be better off on appetite suppressants than on the usual remedies. At the very least, weight loss will control their complications in a more physiologic manner.

Dr. Mike Clark, Ph. D. is the Director of Education & Research for Natural Bio Health. He has a Doctorate Degree in Natural Health and has been designated a Diplomate of Anti-Aging Medicine and a Fellow and Advanced Fellow of Anti-Aging, Regeneration & Functional Medicine.

Mike has been awarded a Certificate in Brain Fitness and Weight Management from the Academy of Anti-Aging Medicine. He is certified by World Link Medical in Advanced Bioidentical Hormone Replacement Therapy and has completed the expert level education in the Mastering the Protocols of Hormone Replacement Therapy.

He is a fourteen year member of the American Academy of Anti-Aging Medicine.

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