Side effects of vancomycin

Vancomycin

Vancomycin is a prescription antibiotic used to treat bacterial infections. Vancocin is the brand name of vancomycin.

The drug works by killing bacteria or preventing their growth.

Vancomycin is commonly used to treat an intestinal illness caused by the bacteria Clostridium difficile (C. diff), which can lead to severe diarrhea.

In 2011, about 450,000 people in the United States contracted a C. diff infection, and about 29,000 people died as a result, according to a study in the New England Journal of Medicine (NEJM).

Vancomycin is also used to treat infections in other parts of the body, and infections in people with heart valve disease or artificial heart valves who are allergic to penicillin.

Doctors may also prescribe vancomycin to prevent endocarditis (inflammation of the lining of the heart) in people who have dental work or other surgeries.

Vancomycin and VRE

Despite the drug’s potency, some bacteria have now developed a resistance to vancomycin.

A deadly “superbug” called vancomycin-resistant Enterococcus (VRE) is a strain of bacteria that infects about 20,000 people each year in the United States, according to the Centers for Disease Control and Prevention (CDC).

VRE also causes about 1,300 deaths in the United States, the CDC reports.

Vancomycin Warnings

You should continue taking vancomycin until the prescription is finished, even if you feel better.

Stopping vancomycin too soon or missing a dose may prevent your infection from being completely cured, as bacteria such as VRE can become resistant to antibiotics (see above).

Before taking vancomycin, tell your doctor and pharmacist if you have any allergies. The drug may contain inactive ingredients that can cause allergic reactions or other problems.

Also, tell your doctor and pharmacist if you have a medical history of kidney disease, hearing problems, any kind of inflammatory bowel disease (IBD), or stomach/intestinal issues.

Elderly patients may be more sensitive to the side effects of vancomycin, which may increase their risk for hearing problems or kidney damage.

Vancomycin and Pregnancy

Vancomycin is generally considered safe to use during pregnancy, but it should only be used in pregnant women when absolutely needed.

The medication does not pass into breast milk and is unlikely to cause harm to a breastfeeding baby, but talk to your doctor before breastfeeding while taking vancomycin.

Vancomycin Hydrochloride for Intravenous Infusion (DBL)

Generic Name: Vancomycin hydrochloride
Product Name: Vancomycin Hydrochloride for Intravenous Infusion (DBL)

Indication

Vancomycin Hydrochloride for Intravenous Infusion is used for the treatment of potentially life threatening infections that cannot be treated with another, less toxic antibiotic (eg: penicillins, cephalosporins).
Staphylococcal infections
It is used against serious Staphylococcal infections (including MRSA) when treatment with other antibiotics has failed or the strain has been shown to be resistant. Sites of infection include:
– bone infection
– pneumonia
– blood infection
– soft tissue and skin infections
If an abscess has formed in relation to the infection, antibiotic treatment should be used only in support of surgical drainage.
Heart valve infection (endocarditis)
Vancomycin is used alone or in combination with an aminoglycoside for the treatment of endocarditis caused by Streptococcus viridans or S. bovis.
Endocarditis caused by Enterococcus species can only be treated with Vancomycin when it is combined with an aminoglycoside.
When endocarditis is caused by Staphylococcus epidermidis the combination of Vancomycin and rifampicin is appropriate.
Infective diarrhoea (colitis)
Vancomycin Hydrochloride for Intravenous Infusion should not be used to treat Staphylococcal colitis or pseudomembranous colitis caused by Clostridium difficile. Vancomycin is appropriate in these settings, but the oral preparation should be used (eg: Vancocin capsules). If absolutely necessary, the IV preparation can be given orally, but capsules should be used in preference.

Action

Vancomycin is from the class of antibiotics known as glycopeptides. It is active against Gram-positive bacteria, but no activity against Gram-negative bacteria, mycobacteria or fungi. It acts by inhibiting the production of a protein needed by bacteria to build their cell walls. Without this component, bacteria cannot survive. This is a similar mechanism of action to the penicillin antibiotics, but Vancomycin acts at a different site and is therefore active against several bacteria that may be resistant to penicillin (eg: S. pneumoniae).
Vancomycin is active against a large list of common and uncommon Gram-positive bacteria, including:
– Staphylococcus aureus (otherwise known as Golden Staph) including the very resistant strains, MRSA
– Streptococci, including Streptococcus pneumoniae, which is an important cause of pneumonia
– Enterococcus faecalis
– Clostridium difficile, a normal bowel bug that can sometimes overgrow during treatment with other antibiotics and cause very serious diarrhoea
– many other bacteria
When used in combination with other antibiotics, Vancomycin can have stronger actions against certain bacteria. For example, when used in combination with aminoglycosides (eg: gentamicin) it has stronger action against S. aureus.
The Vancomycin + rifampicin combination also has stronger activity against many S. aureus strains.
As with treating all infections, it is important to determine the causative organism and susceptibilities before initiating treatment if possible.

Dose advice

Vancomycin Hydrochloride for Intravenous Infusion is for intravenous use only. It should not be used intramuscularly. 1 500mg vial should be mixed with 10ml water for injection. The 1g vial should be mixed with 20ml water for injection. Further dilute with 100ml sodium chloride 0.9% or glucose 5% (200ml for 1g vial) and infuse at a rate of no less than 1hr per 500mg. Less dilution may be used in patients on fluid restriction, but infusion related events increase with any degree of concentration.
The reconstituted solution (in water for injection only) may be stored at 2-8â??aC for up to 96 hours, while the further diluted solution is stable for 28 days at this temperature. Despite this stability, solutions of Vancomycin should be used within 24 hours to reduce microbiological hazard.
Adults
– 500mg every six hours; or
– 1g every 12 hours
– 500mg dose should be infused over no less than 60 minutes
Adults with impaired renal function and the elderly
– dosage adjustment must be made according to creatinine clearance, with the Vancomycin dose being about 15 times the creatinine clearance, for example:
– creatinine clearance 100ml/min: Vancomycin dose: 1,545mg/24hours
– 80ml/min: 1,235mg/24hours
– 50ml/min: 770mg/24hours
– 20ml/min: 310mg/24hours
Children
– 10mg/kg every six hours
– ensure each dose is administered over no less than 60 minutes
Neonates and infants
– 10mg/kg every 12 hours (first week of life) or every 8 hours (until one month of age)
– administer every dose over no less than 60 minutes
– serum Vancomycin concentration monitoring is essential in these patients
Loading dose
– in all patients (including children, neonates and infants) the initial dose should be no less than 15mg/kg, even in patients with renal impairment
Duration of therapy
– most infections show some response to Vancomycin within 48-72hours, but duration of therapy ultimately depends on severity and type of infection
– at least three weeks of treatment is required for the treatment of staphylococcal endocarditis
Oral treatment for colitis
– oral Vancomycin preparations such as Vancocin capsules are preferred for treatment of colitis, but the IV preparation can be used
– 1 vial (500mg) should be diluted in 30ml of distilled water (with flavouring if desired) and given to the patient to drink or administered via nasogastric tube if necessary

Schedule

S4

Common side effects

* Inflammation of the vein used for infusion may be experienced with use of Vancomycin, with such symptoms as:
– itching
– redness
– swelling
This can be reduced if the site of infusion is regularly changed.
* Vancomycin has a very bad taste if taken orally, it can be flavoured with sweet syrups if desired.

Uncommon side effects

* Injection-related reactions are seen with rapid infusion of Vancomycin
– serious adverse effects may result such as: exaggeration of hypotension, shock, cardiac arrest
– flushing, hives and red and itching skin may also be seen
* Patients with leukaemia being treated with Vancomycin may experience nausea, diarrhoea and less often, vomiting.

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For further information talk to your doctor.

Generic Name: vancomycin (oral) (VAN koe MYE sin)
Brand Names: FIRST-Vancomycin, Vancocin HCl Pulvules

Medically reviewed by Drugs.com. Last updated on Mar 18, 2019.

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What is vancomycin?

Vancomycin is an antibiotic. When taken by mouth it fights bacteria in the intestines.

Vancomycin is used to treat an infection of the intestines caused by Clostridium difficile, which can cause watery or bloody diarrhea. It is also used to treat staph infections that can cause inflammation of the colon and small intestines.

Oral vancomycin works only in the intestines. This medicine is not normally absorbed into the body and will not treat other types of infection. An injection form of this medication is available to treat serious infections in other parts of the body.

Vancomycin may also be used for purposes not listed in this medication guide.

Important information

Oral vancomycin works only in the intestines and will not treat infections in other parts of the body. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Vancomycin can cause temporary or permanent hearing loss. Stop using this medication and call your doctor at once if you have any hearing problems or ringing in your ears.

To be sure this medication is not causing harmful effects, your hearing will need to be tested on a regular basis. Visit your doctor regularly.

Take vancomycin for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. This medicine will not treat a viral infection such as the common cold or flu.

Before taking this medicine

You should not take this medication if you are allergic to vancomycin.

To make sure vancomycin is safe for you, tell your doctor if you have:

  • an intestinal disorder such as inflammatory bowel disease, Crohn’s disease, or ulcerative colitis;

  • kidney disease;

  • hearing problems; or

  • if you are receiving any IV antibiotics.

FDA pregnancy category C. It is not known whether vancomycin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Vancomycin can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Side effects on the kidneys may be more likely in older adults taking this medicine.

How should I take vancomycin?

Take vancomycin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Taking more of this medicine will not make it more effective, and may cause serious or life-threatening side effects.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Vancomycin will not treat a viral infection such as the common cold or flu.

If you use this medication long-term, you may need frequent medical tests at your doctor’s office.

Shake the oral suspension (liquid) well just before you measure a dose.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Store vancomycin capsules at room temperature, away from heat and moisture.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Vancomycin side effects

Get emergency medical help if you have any of these signs of an allergic reaction to vancomycin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Certain side effects may occur if your body absorbs vancomycin through the intestinal walls. Call your doctor at once if you have:

  • increased diarrhea that is watery or bloody;

  • hearing loss, ringing in your ears;

  • kidney problems–swelling, rapid weight gain, pain in your side or lower back, little or no urinating; or

  • low potassium–confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.

Common vancomycin side effects may include:

  • nausea; or

  • stomach pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect vancomycin?

Other drugs may interact with vancomycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2020 Cerner Multum, Inc. Version: 10.02.

Related questions

  • Can you drink alcohol while taking vancomycin?
  • What is the difference between Firvanq and the CutisPharma FIRST-Vancomycin Compounding Kit?

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  • Vancomycin Capsules
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  • Vancomycin (Advanced Reading)
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Other brands: Vancocin, Firvanq, Vancocin HCl, Vancocin HCl Pulvules

Professional resources

  • Vancomycin Hydrochloride (AHFS Monograph)
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  • Bacterial Endocarditis Prevention
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Vancomycin Injection

SIDE EFFECTS

Infusion-Related Events

During or soon after rapid infusion of vancomycin, patients may develop anaphylactoid reactions, including hypotension (see Animal Pharmacology), wheezing, dyspnea, urticaria, or pruritus. Rapid infusion may also cause flushing of the upper body (“red neck”) or pain and muscle spasm of the chest and back.

These reactions usually resolve within 20 minutes but may persist for several hours. Such events are infrequent if vancomycin is given by a slow infusion over 60 minutes. In studies of normal volunteers, infusion-related events did not occur when vancomycin was administered at a rate of 10 mg/min or less.

Nephrotoxicity

Renal failure, principally manifested by increased serum creatinine or BUN concentrations, especially in patients administered large doses of vancomycin, has been reported rarely. Cases of interstitial nephritis have also been reported rarely. Most of these have occurred in patients who were given aminoglycosides concomitantly or who had preexisting kidney dysfunction. When vancomycin was discontinued, azotemia resolved in most patients.

Gastrointestinal

Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS).

Ototoxicity

A few dozen cases of hearing loss associated with vancomycin have been reported. Most of these patients had kidney dysfunction or a preexisting hearing loss or were receiving concomitant treatment with an ototoxic drug. Vertigo, dizziness, and tinnitus have been reported rarely.

Hematopoietic

Reversible neutropenia, usually starting 1 week or more after onset of therapy with vancomycin or after a total dosage of more than 25 g, has been reported for several dozen patients. Neutropenia appears to be promptly reversible when vancomycin is discontinued. Thrombocytopenia has rarely been reported. Although a causal relationship has not been established, reversible agranulocytosis (granulocytes <500/mm3) has been reported rarely.

Phlebitis

Inflammation at the injection site has been reported.

Miscellaneous

Infrequently, patients have been reported to have had anaphylaxis, drug fever, nausea, chills, eosinophilia, rashes including exfoliative dermatitis, Stevens-Johnson syndrome, and vasculitis in association with administration of vancomycin.

Chemical peritonitis has been reported following intraperitoneal administration of vancomycin (see PRECAUTIONS).

Post Marketing Reports

The following adverse reactions have been identified during post-approval use of vancomycin. Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Skin And Subcutaneous Tissue Disorders

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS)

Read the entire FDA prescribing information for Vancomycin Injection (Vancomycin Hydrochloride Injection)

Val-Vancomycin

How does this medication work? What will it do for me?

Vancomycin belongs to the group of medications known as antibiotics. It works by killing the bacteria that are causing the infection.

The oral form is used to treat certain infections of the gastrointestinal tract.

The intravenous (IV) form of this medication is used to treat serious or life-threatening infections that have not been successfully treated with other antibiotics, or where penicillins cannot be used. These infections may involve the bones, lungs, blood, and heart.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Each sterile vial contains a lyophilized plug of vancomycin hydrochloride equivalent to either 500 mg, 1 g or 10 g of vancomycin base. When reconstituted with Sterile Water for Injection, USP, it forms a clear solution with pH of 4.0 (2.5 to 4.5). May contain hydrochloric acid and/or sodium hydroxide for pH adjustment.

How should I use this medication?

The usual oral dose for adults is 125 mg to 500 mg taken every 6 to 8 hours for 7 to 10 days.

The usual intravenous, (into a vein), or IV dose for adults is 500 mg given every 6 hours or 1g given every 12 hours. For IV injections, the dose of this medication will be administered by your doctor or health care professional. The length of treatment with IV vancomycin depends on the severity of the infection and the response to the medication.

For children, the oral form (given by mouth) is based on body weight and is given in 3 or 4 daily doses for 7 to 10 days. The IV form of vancomycin, also based on body weight, is given every 6 hours. The total daily dose should not be greater than 2,000 mg.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. Finish all of this medication, even if you start to feel better. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Vancomycin should not be used by anyone who is allergic to vancomycin or to any of the ingredients of the medication.

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed,and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • additional side effects associated with IV administration of vancomycin include:
    • dizziness
    • flushing, redness, rash, itching, pain in the back and neck
    • severe decrease in blood pressure
  • chills
  • nausea
  • taste changes
  • vomiting

Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a severe allergic reaction (e.g., hives; difficulty breathing; swelling of the mouth, tongue, lips, or throat)
  • symptoms of a severe skin rash (e.g., blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Hearing loss: Vancomycin can cause hearing loss. People with a history of hearing loss should not take this medication if possible. If you experience any hearing loss, dizziness, or ringing ears while taking this medication, contact your doctor immediately.

Infusion reactions: IV administration of vancomycin can cause a reaction that includes severely reduced blood pressure, nausea, chills, fever, shortness of breath, and itching. If you experience any of these symptoms, let your doctor or nurse know immediately. Vancomycin may be able to be given if it is administered more slowly.

Intestinal inflammation: People with conditions associated with inflammation of the intestines (e.g., Crohn’s disease, ulcerative colitis) may be at higher risk for side effects, when they take vancomycin capsules, especially if they also have impaired kidney function. Your doctor will monitor you closely for side effects.

Kidney function: Reduced kidney function or kidney disease may cause this medication to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Vancomycin can cause kidney damage. If you experience symptoms of reduced kidney function such as decreased urine production, swelling, fatigue, abdominal pain, let your doctor know as soon as possible.

Overgrowth of organisms: During prolonged or repeated treatment with vancomycin, other bacteria or fungi may be allowed to overgrow. If your condition does not improve or worsens while taking this medication, contact your doctor.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are receiving IV vancomycin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Premature neonates and young infants may require regular blood tests to ensure that the child is receiving the most appropriate dose.

Seniors: Seniors may be more likely to experience side effects associated with vancomycin as a result of reduced kidney function. They may need a lower dose or be put on a less frequent dosing schedule.

What other drugs could interact with this medication?

There may be an interaction between vancomycin and any of the following:

  • aminoglycoside antibiotics (e.g., tobramycin, gentamicin)
  • BCG vaccine (tuberculosis vaccine)
  • cholestyramine (oral dosage form of vancomycin only)
  • cisplatin
  • colestipol (oral dosage form of vancomycin only)
  • neuromuscular blocking agents (e.g., tubocurarine, pancuronium)
  • nonsteriodal anti-inflammatory medications (NSAIDs; e.g., ibuprofen, naproxen)
  • sodium picosulfate
  • typhoid vaccine

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2020. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Val-Vancomycin

Side Effects

Nausea or stomach upset may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: dizziness, hearing problems (such as ringing in the ears, hearing loss), easy bruising/bleeding, signs of kidney problems (such as change in the amount of urine). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

  • hypokalemia
  • ototoxicity
  • nephrotoxicity
  • urinary tract infection
  • fever
  • fatigue
  • dysgeusia
  • peripheral edema
  • nausea
  • vomiting
  • flatulence
  • diarrhea
  • abdominal pain with cramps

Drug Interactions

(See also How to Use section.) Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Although most antibiotics are unlikely to affect hormonal birth control such as pills, patch, or ring, a few antibiotics (such as rifampin, rifabutin) can decrease their effectiveness. This could result in pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more details.

Vancomycin injection comes as a powder to be added to fluid and injected intravenously (into a vein). It is usually infused (injected slowly) over a period of at least 60 minutes once every 6 or 12 hours, but may be given every 8 hours in newborn babies. The length of your treatment depends on the type of infection you have.

You may experience a reaction while you receive a dose of vancomycin injection, usually during your infusion or soon after your infusion has completed. Tell your doctor immediately if you experience any of these symptoms while you receive vancomycin injection: dizziness, wheezing, shortness of breath, itching, hives, flushing of the upper body, or muscle pain or spasm of the chest and back.

You may receive vancomycin injection in a hospital or you may use the medication at home. If you are using vancomycin injection at home, use it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or other healthcare provider to explain any part you do not understand. Use vancomycin injection exactly as directed. Do not infuse it more quickly than directed. Do not use more or less of it or use it more often than prescribed by your doctor.

If you will be using vancomycin injection at home, your healthcare provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing vancomycin injection.

You should begin feeling better during the first few days of your treatment with vancomycin injection. If your symptoms do not improve, or if they get worse, call your doctor.

Use vancomycin injection until you finish the prescription, even if you feel better. If you stop using vancomycin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

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