Side effects of cytomel


How does this medication work? What will it do for me?

Liothyronine is used to treat hypothyroidism (low blood levels of thyroid hormone), goiter (swelling in the thyroid gland), and myxedema (the body’s changes associated with prolonged low blood levels of thyroid hormone). It may also be used to aid the diagnosis of hyperthyroidism (high levels of thyroid hormone).

Thyroid replacement therapy such as liothyronine is used when the thyroid gland does not secrete enough thyroid hormone (hypothyroidism). Thyroid hormone is necessary for maintaining the correct metabolic rate of body tissues. Liothyronine works quickly to restore the normal function of tissues and organs and must be taken on a daily basis to be effective. Replacement thyroid hormone therapy usually needs to be taken for life.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

5 µg
Each round, flat-faced, bevel-edges, compressed white tablet, embossed with “JMI” on one side and “D14” on the other side, contains liothyronine sodium equivalent to liothyronine 5 µg. Nonmedicinal ingredients: calcium sulfate, gelatin, starch, stearic acid, sucrose, and talc.

25 µg
Each round, flat-faced, bevel-edges, compressed white tablet, embossed with “JMI” on one side and scored on the other side, contains liothyronine sodium equivalent to liothyronine 25 µg. Nonmedicinal ingredients: calcium sulfate, gelatin, starch, stearic acid, sucrose, and talc.

How should I use this medication?

The starting adult dose of liothyronine to treat hypothyroidism is 25 µg daily. Based on the results of laboratory tests to determine the amount of thyroid hormone in your blood, your doctor will increase your dose of liothyronine gradually, every 1 to 2 weeks until an appropriate level of thyroid hormone is available in the bloodstream. Do not change the way you take this medication without consulting your doctor.

The starting dose of liothyronine for children when treating hypothyroidism is 5 µg daily, which will be increased every 3 to 4 days until an appropriate response occurs.

The starting adult dose of liothyronine to treat goiter or myxedema is 5 µg daily. Again, based on blood tests, your doctor will gradually increase your dose of liothyronine every 1 to 2 weeks until an appropriate response occurs.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor.

This medication is to be taken once daily, usually before breakfast. Replacement thyroid hormone therapy usually needs to be taken for life.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature. Keep out of reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not take liothyronine if you:

  • are allergic to liothyronine or any ingredients of the medication
  • have certain uncorrected problems of the adrenal glands
  • have untreated thyrotoxicosis (too much thyroid hormone in the blood)
  • have recently had a heart attack

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • headache

Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • confusion
  • diarrhea
  • dizziness
  • fast or irregular heartbeat
  • fatigue
  • fever
  • increased appetite
  • menstrual changes
  • sweating
  • signs of an allergic skin reaction (e.g., rash, itchiness)
  • trouble sleeping
  • weight loss

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • chest pain
  • signs of a heart attack (e.g., chest pain, anxiety, pressure or squeezing sensation in the chest, paleness, shortness of breath, pain spreading to shoulders, neck, jaw)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Diabetes: Liothyronine may cause blood sugar to increase and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using this medication.

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Heart disease: Starting liothyronine may cause the heart to work harder than it has been used to. This can cause symptoms of angina or other heart disease to worsen. If you have angina or other heart disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Pregnancy: Liothyronine does not cross the placenta, therefore it does not directly affect the development of an unborn baby. During pregnancy, your doctor will probably want to do blood tests to make sure the level of thyroid in the blood stream is appropriate. This medication is safe to use during pregnancy.

Breast-feeding: This medication passes into breast milk in small amounts. It is important to continue taking thyroid hormone even when you are breast-feeding. Inform your doctor if you are breast-feeding or intending to breast-feed while taking liothyronine.

Seniors: Older people may be more sensitive to the effects of liothyronine and should be watchful for side effects, particularly those involving the heart.

What other drugs could interact with this medication?

There may be an interaction between liothyronine and any of the following:

  • amphetamines (e.g., dextroamphetamine)
  • antacids that contain aluminum or calcium
  • antidiabetes medications (e.g., insulin, glyburide, metformin)
  • beta-blockers (e.g., metoprolol, propranolol)
  • birth control pills
  • calcium polystyrene
  • calcium supplements (e.g., calcium carbonate, calcium citrate)
  • carbamazepine
  • cholestyramine
  • colestipol
  • diet pills
  • digoxin
  • estrogens
  • iron supplements (e.g., ferrous fumarate, ferrous sulphate)
  • ketamine
  • phenytoin
  • rifampin
  • simethicone
  • sodium iodide I131
  • sodium polystyrene
  • sympathomimetic medications (e.g., epinephrine, norepinephrine)
  • theophyllines (e.g., aminophylline, oxtriphylline, theophylline)
  • tricyclic antidepressants (e.g., amitriptyline, imipramine)
  • warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2020. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source:

Guidelines are skeptical about adding liothyronine to levothyroxine as a treatment for hypothyroidism, but some patients are convinced that the combination works better for them.

Your hypothyroid patient complains that she still does not feel well despite taking levothyroxine (LT4). She has been researching on the Internet, and has read many accounts from patients in her situation who say that they feel much better when their doctors add another thyroid hormone “called T3 or something…”

So, you face a dilemma. You have based her treatment on the American Thyroid Association (ATA) guideline that says that levothyroxine (LT4) is the standard treatment. And clinical trials have not found a benefit in adding liothyronine (LT3).

LT4 became the treatment of choice following the discovery that the thyroid primarily makes the prohormone thyroxine (T4), which tissues around the body convert into the active hormone, triiodothyronine (T3). T4 has a half-life of a week or so, while T3’s half-life is less than a day. It has worked for most patients to take T4 and let the body do the conversion—except for some 5% to 10% of patients who say it doesn’t work for them. Is there a problem in giving them LT3 as well?

Four thyroid experts interviewed by Endocrine News all called this combination therapy controversial — but not one of them would refuse to give it a try in an appropriate patient who requested it.

“It is true that levothyroxine has been used for decades and the overwhelming majority of patients are satisfied, but a significant minority are not satisfied,” says Douglas S. Ross, MD, professor of medicine at Harvard Medical School and co-director of Thyroid Associates at Massachusetts General Hospital in Boston. “Why not attempt to mimic normal blood levels with T4 and T3?”

“It is unquestionable that some patients will tell you that the day they were switched from levothyroxine to combination therapy, ‘a light bulb went on in my brain,’ or ‘I can think again.’ There has got to be something there,” says Antonio C. Bianco, MD, PhD, professor of medicine and vice dean of clinical affairs at Rush University Medical Center in Chicago, Illinois.

What the Guidelines Say

Bianco’s view is particularly interesting because he co-chaired the task force that prepared ATA’s latest hypothyroidism guidelines in 2014, which concluded that LT4 should remain the standard in treatment for hypothyroidism: “We found no consistently strong evidence for the superiority of alternative preparations (e.g., levothyroxine-liothyronine combination therapy, or thyroid extract therapy, or others) over monotherapy with levothyroxine in improving health outcomes.” Even among patients who “feel unwell on levothyroxine therapy alone, there is currently insufficient evidence to support the routine use of a trial of a combination of levothyroxine and liothyronine therapy outside a formal clinical trial.”

“We just don’t have the data yet to change my mind that adding T3 to T4 actually results in a superior product.” – James V. Hennessey, MD, director of clinical endocrinology, Beth Israel Deaconess Medical Center, Boston, Mass.

The European Thyroid Association guideline says that “combination therapy should be considered solely as an experimental treatment” overseen by “accredited internists/endocrinologists, and discontinued if no improvement is experienced after three months.”

The most recently published guideline — from the Italian Thyroid Association in late 2016 — says that combination therapy is “generally not recommended” but a trial “may be considered to improve adherence to treatment or patient well-being.” Perhaps in a concession to reality, it outlines a protocol for combination therapy.

Literature Lacks Evidence

Combination treatment is clearly in use; Bianco estimates that about half the hypothyroid patients referred to him are on it. Much of the interest stems from a tantalizing 1999 study of 33 Lithuanian hypothyroid patients (most of whom were receiving suppressive LT3 doses for thyroid cancer treatment) that concluded that combination therapy “may improve mood and neuropsychological function.” Those findings have proven difficult to duplicate. “Subsequently, there were 10 or 12 studies designed to look at combination therapy in a systematic manner using different ratios of thyroxine to T3. For the most part, none of those studies showed any consistent effect, and four meta-analyses of the literature concluded that there was no consistent benefit,” says James V. Hennessey, MD, director of clinical endocrinology at Beth Israel Deaconess Medical Center.

“It is unquestionable that some patients will tell you that the day they were switched from levothyroxine to combination therapy, ‘a light bulb went on in my brain,’ or ‘I can think again.’ There has got to be something there.” – Antonio C. Bianco, MD, PhD, professor of medicine and vice dean of clinical affairs at Rush University Medical Center in Chicago, Ill.

But the effectiveness of combination therapy remains an open question because of flaws in previous studies and a lack of well-designed, randomized trials, according to Jacqueline Jonklaas, MD, PhD, MPH, associate professor of endocrinology and metabolism at Georgetown University Medical Center and co-chair of the ATA guideline task force: “In the 13 or so combination therapy trials that have been done, the majority only gave the T3 once a day, a few of them gave it twice a day, and that really isn’t enough to maintain nice steady levels of T3.”

Bianco agrees: “When we give combination therapy, we are actually not normalizing serum T3. We are creating pulses of T3. So during a few hours you have a higher level of T3. Then a few hours later, you have a lower level than what you want. Unless we develop a delivery system to provide a steady level of T3, we are not in a position to answer whether combination therapy is better or worse than monotherapy.”

“People have been talking for decades about a time-released T3 medicine,” says Ross. “But that appears to be difficult to make because pharmaceutical companies have not come up with it yet,” despite a potential market of millions of patients. Correct dosing might require taking LT3 several times a day, and for most people compliance would be an issue.

The inability of researchers who design clinical trials to figure out an effective system to administer T3 might give pause to clinicians considering this treatment for hypothyroidism.

The Ratio Rationale

Ross suggests that a logical treatment strategy is to try to mimic the normal physiological ratio of T4 to T3 of about 14 to 1: “The clinical literature is muddled by the fact that most people who have tried to give T4 and T3 have given way too much T3. There is one study by Escobar-Morales which actually gave the appropriate ratio of T4 and T3. And while the researchers could not demonstrate any physiologic benefit, patients preferred the combination of T4 and T3.”

“There is a problem with using superphysiologic levels of T3, so I don’t suggest anyone take extract. But if you provide T4 and T3 at the appropriate ratio, why should that be considered problematic?” – Douglas S. Ross, MD, professor of medicine, Harvard Medical School; co-director, Thyroid Associates at Massachusetts General Hospital, Boston, Mass.

But basing treatment for hypothyroidism on patients’ preferences may not lead to the best outcomes. “T3 has also been used by psychiatrists as adjunctive therapy for depression, so part of this feeling better issue may have to do with the effects of giving too much thyroid hormone,” Ross says. “If you give people a little bit too much T4, in general they feel better. Their mental health is better, but their physical health is a little bit impaired. They will complain that they aren’t sleeping as well, but they feel better overall and they are less depressed. It may simply be that slightly hyperthyroid people feel better.”

The T4 to T3 ratio is one reason why all the guidelines recommend LT4 over thyroid extracts. Extracts from pig thyroid glands are rich in T3, at a T4 to T3 ratio of 4 to 1, which the guidelines say raises safety concerns.

The guidelines also agree that there are some circumstances in which combination therapy should be avoided, such as pregnancy. “The fetus seems to run on maternal T4, rather than T3, and so there is a concern that the fetuses of women taking extract or combination therapy may not have appropriate neurologic development,” Ross says.

“In the 13 or so combination therapy trials that have been done, the majority only gave the T3 once a day, a few of them gave it twice a day, and that really isn’t enough to maintain nice steady levels of T3.”- Jacqueline Jonklaas, MD, PhD, MPH, associate professor of endocrinology and metabolism, Georgetown University Medical Center, Washington D.C.

Another patient population where caution is warranted is the elderly. The ATA guidelines note that “the elderly are more susceptible to the adverse effects of thyroid hormone excess, especially heart conditions such as atrial fibrillation or osteoporotic fractures,” so T3 peaks could be worrisome.

In Conclusion…or Inconclusive

“We just don’t have the data yet to change my mind that adding T3 to T4 actually results in a superior product,” Hennessey says. But he adds: “I see patients on a regular basis who say, ‘I am completely dysfunctional.’ Then someone offers them T3, and the next day they are up performing their activities of daily living as if they have never had thyroid disease. In my opinion, it happens way too quickly for it to actually be thyroid hormone action. But the patients are wedded to it. I tell them that I’m not sure that it was the T3 that did it. But as long as they are not doing any harm by taking too much T3, I am certainly willing to continue to be supportive of their care.”

Ross does not see the harm in trying a different approach when patients are not satisfied with LT4 alone: “There is a problem with using superphysiologic levels of T3, so I don’t suggest anyone take extract. But if you provide T4 and T3 at the appropriate ratio, why should that be considered problematic?”

Health & Lifestyle

Contents: 1. Cytomel description 2. Cytomel Characteristics 3. Stacking and Use 4. How and where buy Cytomel online
Cytomel description Drug Class: Synthetic thyroid hormone
Pharmaceutical Name: Liothyronine sodium
Brand Name: Cytomel
Effective Dose: 25-100 mcg/day
Cytomel is not a steroid, but more a of a cutting aid. It’s a synthetic form of the thyroid hormone tri-iodio-thyronine or T3, made up of a metabolite of the amino acid tyrosine and 3 iodine ions. In the body it in turn is made from another hormone, T4, which is secreted by the thyroid under influence of the pituitary hormone TSH (Thyroid stimulating hormone). If a shortage of either TSH or T4 is noted, usually doctors may opt for a replacement therapy. These days the most common prescription is synthetic T4 (synthroid), but in more severe cases of permanent thyroid dysfunction, the choice is given to Cytomel. Simply because T4 is mostly active through its conversion to T3 and T3 is 4-5 times stronger than T4 on a mg for ?g basis.
How to Use Cytomel: Bodybuilders take advantage of these characteristics and stimulate their metabolism by taking Cytomel, which causes a faster conversion of carbohydrates, proteins, and fats. Bodybuilders, of course, are especially interested in an increased lipolysis, which means increased fat burning. Competing bodybuilders, in particular, use Cytomel during the weeks before a championship since Cytomel helps to maintain an extremely low fat content, without necessitating a hunger diet. Athletes who use low dosages of Cytomel report that by the simultaneous intake of steroids, the steroids become mote effective, most likely as the result of the faster conversion of protein. Nowadays, instead of Cytomel, athletes use Clenbuterol which is becoming more and more popular. Those who combine these two compounds will burn an enormous amount of fat. Cytomel is also popular among female bodybuilders. Since women generally have slower metabolisms than men, it is extremely difficult for them to obtain the right form for a competition given today’s standards. A drastic reduction of food and calories below the 1000 caloric/day mark can often be avoided by taking Cytomel. Women, no doubt, are more prone to side effects than men but usually get along well with 50 mcg/day. It is also important that Cytomel not be taken for more than six weeks. At least two months of abstinence from the drug needs to follow. Those who take high dosages of Cytomel over a long period of time are at risk of developing a chronic thyroid insufficiency.
In bodybuilding circles Cytomel is mostly used as fat-loss drug. Thyroid hormones are often referred to as the metabolic regulators of the body. High levels of T3 speed up the metabolism of an individual, allowing him to burn more calories and use calories more sufficiently. Generally ectopmorphic body-types have very high thyroid levels and in some cases a slight undiagnosed form of hyperthyroidism. Both hyper-and hypothyroidism can have severe consequences on an individual, such as goiters and other nasty stuff, so messing with your thyroid is not something I would advise to beginners. As with insulin, misuse of this compound can leave you dependent on exogenous T3 for the rest of your life (remember Frank Zane?). So some caution and research is required before putting Cytomel in your body. Generally cycles should be limited to 4-6 weeks tops, I recommend 3 and alternating cycles with 3-week cycles of clenbuterol. But most importantly, to avoid a crash or a shock to the thyroid function doses need to be built up over time and tapered off again. More so for cytomel than for any other drug in existence.
Bill Llewellyn says that Cytomel is not a drug to start off on, and that use of milder drugs like T4 (Synthroid) or triacana can help ease a person into the use of T3. I’m inclined to disagree here however. Triacana is weak compound and I find of little use. Its not easily found anymore and not cheap either. T4 is basically similar to Cytomel except that its weaker. Something that users normally compensate with higher doses and sends them down a similar lane as simply using cytomel. Agreed, cytomel is NOT a drug for beginners, but with adequate research, experience with diet and some self-control, I don’t see why cytomel shouldn’t be the first thyoid compound used. But for recreational users looking for a fatburner, I still suggest using clenbuterol over cytomel for all intents and purposes. Cytomel is much more powerful, but clenbuterol is a lot safer for use. The results are easier to maintain with clenbuterol as well. Negative feedback in the thyroid may decrease natural levels of T3 in the body, causing a decrease of metabolic rate after coming off a cycle of T3. That can cause a rebound effect during which a lot of weight is gained back.

Cytomel Dosage: As for the dosage, one should be very careful since Cytomel is a very strong and highly effective thyroid hormone. It is extremely important that one begins with a low dosage, increasing it slowly and evenly over the course of several days. Most athletes begin by taking one 25 mcg tablet per day and increasing this dosage every three to four days by one additional tablet. A dose higher than 100 mcg/day is not necessary and not advisable.
For competitive bodybuilders Cytomel is an almost unmissable aid in contest preparation, along with clenbuterol and non-aromatizing steroids such as stanazolol, trenbolone, methenolone and so forth…
Stacking and Use: It can be stacked or alternated with Clenbuterol. I usually recommend to alternate, three weeks clen with three weeks cytomel, since clen loses most of its benefits after a short period of time and using cytomel for extended time-periods will increase the risk of permanent thyroid failure. Neither drug is terribly expensive so I see no problem in this. Some opt to use them together for 3-4 weeks, and then use an over the counter ECA stack to bridge with for an equal period of time, but I’m not such a big fan of that. Which naturally doesn’t mean its not effective, that’s just a personal opinion. Running it for three weeks, one could choose for a schedule as follows: 25/25/25/50/50/50/75/75/75/100/100/100/75/75/75/50/50/50/25/25/25 ?g/day. If taken for 4 weeks, then run each dose for 4 days, 5 weeks then each dose for 5 days and so on. It is extremely important that the doses are tapered on and off and that a cycle never exceeds 6 weeks at the most.
Side Effects of Cytomel: Possible side effects are heart palpitation, trembling, irregular heartbeat, heart oppression, agitation, shortness of breath, excretion of sugar through the urine, excessive perspiration, diarrhea, weight loss, psychic disorders, etc., as well as symptoms of hypersensitivity. Our experience is that most symptoms consist of trembling of hands, nausea, headaches, high perspiration, and increased heartbeat. These negative side effects can often be eliminated by temporarily reducing the daily dosage. Those who use Cytomel over several weeks will experience a decrease in muscle mass.
As far as adding products, no ancillaries are needed, but its highly recommended that this is only used when anabolic/androgenic steroids are also being used. First of all the extra free calories work with the steroids to enhance results, but also because an increased level of thyroid hormones can be extremely catabolic and the use of anabolic compounds to counter muscle loss is a requirement here.
How and where to buy Cytomel steroid online? – is the fastest way to buy Cytomel and other anabolic steroids online. Steroid products profiles, steroids experience and many other useful information for bodybuilders.

Cytomel is a T3 only thyroid medication which happens to also be the most powerful thyroid medication available.

The only problem? It can sometimes be associated with hair loss and, even though the medication is great, you should be aware of this problem if you are using it or thinking about using it.

Before we jump in, just realize that Cytomel is the brand name T3 medication but this information also applies to liothyronine which is the generic version of Cytomel.

There are 3 main ways that Cytomel may cause hair loss:

#1. Hair loss related directly to the medication.
– The first cause of hair loss has to do with the medication itself. The good news is that this is typically temporary and should resolve within 2-4 months (3-6 months at most). The exact mechanism of this hair loss is not known. The treatment for this issue is to give it time and to be patient!

#2. Hair loss related to an excessively high dose.
– This cause of Cytomel-related hair loss is dose-dependent and only occurs if your dose is too high. Because Cytomel is the strongest thyroid medication it is possible for you to take too much which may result in a hyperthyroid state and hair loss. The treatment for this issue is to simply reduce your dose.

#3. Hair loss related to insufficient dosing.
– Lastly, and perhaps most common, is hair loss related to an insufficient dose. Because Cytomel is so strong, doctors tend to underdose patients when they start taking it. This may result in a persistent hypothyroid state which leads to persistent hair loss. The treatment for this issue is to simply increase your dose.

Despite these potential issues I still believe that Cytomel remains as a great medication (perhaps one of the best). If you are considering using Cytomel don’t let this information scare you away because most people who use it do NOT experience hair loss.

I’m Dr. Westin Childs and I focus on thyroid health, hormone balance, and weight loss. I write about thyroid disorders, weight loss, insulin resistance, estrogen/progesterone balance on my blog. I truly believe that hormone balance is the key to managing your weight, your mood and your quality of life which is why I’m so passionate about it.

This video is not intended to be used as medical advice. If you have questions about your health please consult your physician or primary care provider. Dr. Westin Childs goes to great lengths to produce high-quality content but this is NOT a substitute for medical care.

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 8/21/2018

Cytomel (liothyronine sodium) is a synthetic thyroid hormone used to treat hypothyroidism (low thyroid hormone). Cytomel is also used to treat or prevent goiter (enlarged thyroid gland), and is also given as part of a medical tests for thyroid disorders. Cytomel is available in generic form. Common side effects of Cytomel include:

  • nausea.

In rare cases, temporary hair loss may occur during the first few months of starting Cytomel (especially in children). Tell your doctor immediately if you experience unlikely but serious signs of too much thyroid hormone including:

  • headache,
  • irritability,
  • trouble sleeping,
  • nervousness,
  • increased sweating,
  • heat intolerance,
  • diarrhea, and
  • menstrual changes.

To treat mild hypothyroidism the recommended starting dose of Cytomel is 25 mcg daily. Usual maintenance dose is 25 to 75 mcg daily. Dosage for other conditions varies. Cytomel may interact with birth control pills or hormone replacement therapy, blood thinners, digoxin, insulin or oral diabetes medication, medications that contain iodine, antidepressants, aspirin or other salicylates, or steroids. Tell your doctor all medications you use. Current information shows Cytomel may be used during pregnancy. Consult your doctor before becoming pregnant. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breastfeeding.

Our Cytomel (liothyronine sodium) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How to Reverse Hair Loss Related to Thyroid Conditions

Along with medication, there are different home remedies you may try to slow hair loss or regenerate hair growth.

Boost iron

Ferritin levels are associated with your iron stores. Low ferritin may contribute to patterned hair loss.

A study on hair loss and iron stores did exclude people with thyroid conditions. The reasoning behind this exclusion is very interesting. Researchers explain that thyroid issues can affect the body’s ferritin levels. Consider having your iron and ferritin tested and supplementing as your doctor suggests.

You can purchase an iron supplement online.

Treat nutritional deficiencies

Nutritional deficiencies can contribute to hair loss even without a thyroid condition. Specifically, researchers explain that levels of the following may play a role in hair retention and hair loss:

  • vitamins B-7 (biotin) and B complex
  • zinc
  • copper
  • iron
  • vitamins C, E, and A
  • coenzyme Q10

A multivitamin may help boost your stores. Beware that too much supplementation may lead to hair thinning.

Choose from a variety of multivitamin supplements online.

Eat well

Eating a diet of whole foods is key for your health.

If you eat foods rich in calcium and are being treated for hypothyroidism, try timing them at least four hours after your levothyroxine for the best absorption.

Processed foods, such as sugars, red meat, and fried foods, may cause an inflammatory response. Caffeine and alcohol may contribute as well. Inflammation may worsen your thyroid symptoms, including hair loss.

Add anti-inflammatory foods

Ginger and turmeric are anti-inflammatory foods that may improve endocrine function. Your thyroid is part of the endocrine system, so supporting it may help with symptoms of thyroid disorders.

Try incorporating fresh ginger or turmeric root into cooking. They taste great in anything from stir-fries to smoothies. Discuss supplementation with your doctor.

Consider herbs

Some branches of alternative medicine use specific herbs to treat hair loss from conditions like alopecia. These herbs are taken orally and include:

  • palmetto
  • black cohosh
  • dong quai
  • false unicorn
  • chasteberry
  • red clover

Discuss herbal therapies with your doctor before trying them on your own.

Try essential oils

While there aren’t many studies in this area, researchers have discovered that eucalyptus oil and other plant extracts may reduce hair fallout and improve hair density.

Other oils to try include:

  • Arnica montana
  • Cedrus atlantica
  • Lavandula agustifolia
  • Oscimum sanctum
  • Pilocarpus jabarondi
  • Rosmarinus officinalis
  • Thyme vulgaris

While research suggests there are health benefits, the FDA doesn’t monitor or regulate the purity or quality of essential oils. It’s important to talk with your doctor before you begin using essential oils and use caution when choosing a quality brand. You should also always do a test patch before using and dilute any essential oil in a carrier oil before use.

You can buy eucalyptus essential oil online.

Watch iodine intake

People with autoimmune thyroid disorders should watch their iodine intake. The body uses iodine to make thyroid hormone, so too much may lead to imbalances.

Kelp and other kinds of seaweed are high in iodine and may worsen symptoms, including hair loss. Certain multivitamins and cough syrups may also contain iodine, so read labels carefully.

Treat hair gently

You can slow hair loss by treating your hair with care:

  • Avoid pulling hair into tight braids, buns, or ponytails.
  • Resist twisting or pulling your hair.
  • Use a wide-toothed comb versus harsher brushes when loosening knots.

Changing your routine up a bit may help you from pulling out hair before it would otherwise naturally fall out.

Have patience

It may take several months to notice regrowth. While this may be frustrating, you may consider wearing a wig or other head covering in the meantime.

Emotional support is also important, so ask your doctor about counseling or support groups where you can meet people going through similar situations.

Liothyronine Side Effects

Incidence not known


arm, back, or jaw pain

blurred or double vision

chest pain or discomfort

chest tightness or heaviness


decreased bone mineral density

decreased urine output

delusions of persecution, mistrust, suspiciousness, or combativeness


difficulty breathing

dilated neck vein




extreme tiredness or weakness

eye pain


false or unusual sense of well-being

fast, pounding, or irregular heartbeat or pulse

feeling of discomfort

feeling of unreality



heat intolerance

impaired fertility

increased appetite

increased blood pressure

irregular breathing


itching, skin rash

joint swelling

limp pain in the hip or knee

menstrual changes

mental depression

muscle aches, weakness, or cramps



pain or discomfort in the arms, jaw, back, or neck

quick to react or overreact emotionally

rapidly changing moods


sense of detachment from self or body

severe headache

slow heartbeat

stomach cramps

swelling of the face, fingers, feet, or lower legs

swollen lymph glands


trouble sitting still

trouble sleeping


weight gain or loss

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