Minastrin 24 side effects

Minastrin 24 Fe


The following serious adverse reactions with the use of COCs are discussed elsewhere in the labeling:

  • Serious cardiovascular events and stroke
  • Vascular events
  • Liver disease

Adverse reactions commonly reported by COC users are:

  • Irregular uterine bleeding
  • Nausea
  • Breast tenderness
  • Headache

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to the rates in the clinical trials of another drug and may not reflect the rates observed in practice.

The data presented in Section 6.1 are from a clinical trial conducted with a 24-day regimen of norethindrone acetate 1 mg/ethinyl estradiol 0.020 mg tablets. Minastrin 24 Fe is bioequivalent to these norethindrone acetate/ethinyl estradiol tablets.

Adverse Reactions Leading to Study Discontinuation: Among the 743 women using norethindrone acetate/ethinyl estradiol tablets, 46 women (6.2%) withdrew because of an adverse event. Adverse events occurring in 3 or more subjects leading to discontinuation of treatment were, in decreasing order: abnormal or irregular bleeding (1.3%), nausea (0.8%), menstrual cramps (0.5%), and increased blood pressure (0.4%).

Postmarketing Experience

The following adverse reactions have been identified during post approval use of a 24-day regimen of norethindrone acetate 1 mg/ethinyl estradiol 0.020 mg tablets. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or evaluate a causal relationship to drug exposure.

Adverse reactions are grouped into System Organ Classes.

Vascular disorders: thrombosis/embolism (coronary artery, pulmonary, cerebral, deep vein).

Hepatobiliary disorders: cholelithiasis, cholecystitis, hepatic adenoma, hemangioma of liver.

Immune system disorders: hypersensitivity reaction.

Skin and subcutaneous disorders: alopecia, rash (generalized and allergic), pruritus, skin discoloration.

GI disorders: nausea, vomiting, abdominal pain.

Musculoskeletal and connective tissue disorders: myalgia.

Eye disorders: blurred vision, visual impairment, corneal thinning, change in corneal curvature (steepening).

Infections and infestations: fungal infection, vaginal infection.

Investigations: change in weight or appetite (increase or decrease), fatigue, malaise, peripheral edema, blood pressure increased.

Nervous system disorders: headache, dizziness, migraine, loss of consciousness.

Psychiatric disorders: mood swings, depression, insomnia, anxiety, suicidal ideation, panic attack, changes in libido.

Renal and urinary disorders: cystitis-like syndrome.

Reproductive system and breast disorders: breast changes (tenderness, pain, enlargement, and secretion), premenstrual syndrome, dysmenorrhea.

Cardiovascular: chest pain, palpitations, tachycardia, myocardial infarction.

Read the entire FDA prescribing information for Minastrin 24 Fe (Norethindrone Acetate and Ethinyl Estradiol/Ferrous Fumarate Capsules)

In the summer of 2014, Dr. Laura Schiller, an obstetrician-gynecologist in New York City, suddenly began getting frantic calls. Patients had gone to the pharmacy to pick up their usual prescriptions for the birth control pill Loestrin 24 Fe, only to be told it was no longer available.

Oral contraceptives are not much different today in their essential ingredients than they were thirty years ago. But they have been repackaged and marketed and, often, repatented in new (but not necessarily improved) forms. The dozens of options offer slightly different hormonal mixes and dosing schedules. Women choose a particular pill because for them it produces fewer side effects like bloating, or comes in a more convenient dispensing pack, or just because it has nicer advertising.

Warner Chilcott’s Loestrin 24 Fe was one of the most popular contraceptive pills. It combined a low dose of estrogen in a twenty-four-day cycle and iron; periods were light but predictable. It sold for about $90 retail in the United States and $20 elsewhere in the world. Nonetheless, with U.S. purchases covered largely by insurance, sales of Loestrin 24 Fe climbed 25.4 percent to $89 million in 2012.

To protect its franchise, Warner Chilcott had sued a few drugmakers who planned to make a generic for patent violation in 2011, thereby gaining thirty extra months of protection. The suit never went to court, because Warner Chilcott used a tactic called “pay for delay” to settle: the company gave two drugmakers, Watson and Lupin, various financial incentives in exchange for agreeing to delay their applications to make a generic. The arrangement suited all the manufacturers just fine, but it was clearly bad for patients. According to industry analysts, every six months of delay before generics hit the market can be worth billions in profits or added spending.

By 2014 that strategy had played out, and the first patent for Loestrin 24 Fe was finally slated to expire soon. But before it did, Warner Chilcott had another trick up its sleeve.

It conducted research and development to invent a new chewable form of the pill with a new name, Minastrin 24 Fe, and a new patent. Then Warner Chilcott stopped making the old favorite, Loestrin 24 Fe. There were no generic versions of the pill on the market yet, so patients who wanted to stay with the same formulation of birth control pill had no choice but to switch to the chewable brand.

The advertising for Minastrin touted its benefits; for example, the pill could now be taken even if there was no water available. Most adult women, however, had no desire to chew a birth control pill. Some objected to the artificial sweeteners. The new version cost between $130 and $150 when paying cash with a discount card, depending on the pharmacy— about 30 percent more than the old.

The industry name for this maneuver is “product hopping,” and Warner Chilcott was, historically, a master artist. A lawsuit filed by Mylan Pharmaceuticals alleged that Warner intentionally moved its acne medication Doryx from one form to another three times in order to stymie the launch of a generic. It swapped a capsule for a tablet; developed a version that could be broken up and sprinkled on applesauce; and introduced a new scored pill. Since generics must be identical in dosage and form to the brand-name drug for a pharmacist to substitute, each move succeeded in delaying competition from generics for years.

We live in an age of medical wonders—transplants, gene therapy, lifesaving drugs, and preventive strategies—but the healthcare system remains fantastically expensive, inefficient, bewildering, and inequitable. Who among us hasn’t filled a prescription or opened a medical bill and stared in disbelief at terrifying numbers? And yet we’ve come to accept it as an inevitable burden of being American.

Now that you’ve read about how some unsavory business practices have hijacked our healthcare, you know we have the choice to stop it. This book is a call to arms, as well as a road map for us to fight back personally, politically, and systematically.

So what can you do about the high cost of prescriptions?

Americans comparison shop for cars, bread, electronics, and just about everything else—except prescription drugs. More than half of us regularly take prescription medications, and the contents of these pills, potions, and creams are highly regulated. We should be able to—simply and easily—buy from the cheapest vendor and at the lowest personal cost, but we can’t. From month to month, the price of medicines can change, along with our co-pays, and we don’t find out until we’re picking up our filled prescriptions at the pharmacy counter.

The government will, perhaps, one hopes eventually take action to address burdensome drug expenses, since virtually every politician has recognized this as a major problem. But many of us simply can’t afford to wait for our frustration to overcome DC gridlock, so in the meantime it’s best to adopt some personal strategies to dampen the impact.

Learn more about the contents and cost of the medications you are taking. Many expensive prescription medicines are just reformulations of older versions of the same drugs creatively repatented, not improved. Pills that combine two medicines, extended release tablets, and creams and ointments are often available in older, less expensive forms that are equally effective. For example, you can save a lot of money if you’re willing to take two pills instead of one. (Sometimes those two pills may even be sold over the counter for a fraction of the cost of the combined medication, as in the case of Duexis.)

Don’t equate expense or sudden price hikes with an increase in value; research alternatives. Ask your pharmacist or doctor if there are more cost-effective ways to take your prescribed medications. Many oral contraceptives are more or less interchangeable.

My favorite antibiotic for smearing on infected cuts is a prescription preparation called mupirocin (brand name Bactroban), which is available in ointment or cream form. The clear ointment, which is older and off patent, costs $10 a tube. The white cream, which the drug company created when the ointment’s patent was about to expire, is no better or worse in my experience and costs $115. A doctor writing the prescription likely doesn’t know there’s a huge price difference. Some acne preparations that cost $100 to $300 a month, such as Epiduo, are no more than a far cheaper generic topical antibiotic or a vitamin A derivative combined with peroxide.

Check your insurer’s formulary to find out if different strengths of the medication are covered. One patient saw her co-payments for her usual dose of a thyroid drug quadruple overnight to nearly $300 a month, be- cause that strength was removed from her insurer’s preferred formulary. But she discovered that she could negate the increase if she bought a higher dose (still on formulary) and cut the pills in half.

Shop Around GoodRx.com, a Web site and mobile app, will give you the cash price of every medicine at pharmacies in your area and provides coupons for dis- counts (the price you will pay if you forgo using insurance). A prescription’s price at the pharmacy depends largely on the wholesale prices agreed to by your pharmacy, the drugmaker, the pharmacy benefit manager, and your insurer, plus the markup at the store. In some cases, the full cash price will be less than your insurance co-payment, in part because many chain stores offer rock-bottom cash prices on common pharmaceuticals to get shoppers in the door. If that’s the case, tell the pharmacist you want to pay cash instead.

Consider Imports. If you need to take a drug but really can’t afford it, you may want to consider buying it from a source outside of the United States. The cost is likely to be one-third to one-half of the U.S. price. Experts estimate that each year five million people order medicines abroad, though the real number is almost certainly greater because many people are reluctant to admit to doing something that’s technically against the law (but rarely stopped or prosecuted, if for personal use). I’ve heard from a number of physicians who do so for them- selves. If you decide to go this route, here are a few shopping guidelines:

1. If you’re traveling to a country whose health system you trust, buy refills of medicines there. Pharmacists worldwide can often honor such requests because they have independent prescribing power. (Carrying a prescription helps. A foreign pharmacist may want to confirm that you’re taking the medicine at the advice of a doctor.) A few years ago, the manufacturer’s recommended wholesale price of Advair, a popular asthma inhaler, was $250 in the United States, but $45 (for cash) in Paris. The money you save pays for your airfare to Europe,

2. Rely on overseas mail-order pharmacies to order long-term medicines whose efficacy can be clearly measured, such as those that control cholesterol or an expensive medicine for low-grade type 2 diabetes; neither requires precise results and you can check these parameters to ensure that the medicine you received is working well. Starting a regimen with a foreign substitute might be less well advised for a drug used to prevent organ transplant rejection or seizures (since blood levels of these medicines are notoriously finicky).

Companies like PharmacyChecker.com will help you to ensure that the medicines you are ordering are not fakes. These online clearinghouses vet the pharmacies that sell drugs on their Web sites and source from English-speaking countries, so packaging instructions and warnings labels are understandable.

From An American Sickness by Elisabeth Rosenthal. Reprinted by arrangement with Penguin Books, a member of Penguin Group (USA) LLC, A Penguin Random House Company. Copyright © Elisabeth Rosenthal, 2017.


What was the prescribed dosage? 1-5mg 6-10mg 11-50mg 51-100mg 101-200mg 201-500mg 501mg-1g

Here is the some steps to help you to save money on Minastrin 24 Fe purchase.

  • Read drug prescription
    • What is Minastrin 24 Fe
    • Minastrin 24 Fe side effects
  • Select the most affordable brand or generic drug
  • Frequently asked Questions
    • What other drugs will affect Minastrin 24 Fe?
    • Who should not take Minastrin 24 Fe?
    • How should I take Minastrin 24 Fe?
  • Minastrin 24 Fe reviews

Read drug prescription

It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Minastrin 24 Fe before taking it.

What is Minastrin 24 Fe

Minastrin 24 Fe and norethindrone is a combination drug that contains female hormones that prevent ovulation. Minastrin 24 Fe also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.
Minastrin 24 Fe and norethindrone is used as contraception to prevent pregnancy.
Minastrin 24 Fe and norethindrone may also be used for purposes not listed in Minastrin 24 Fe guide.

Minastrin 24 Fe side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using birth control pills and call your doctor at once if you have:

  • sudden numbness or weakness, sudden severe headache, slurred speech, problems with vision or balance;
  • sudden cough, wheezing, rapid breathing, coughing up blood;
  • pain, swelling, warmth, or redness in one or both legs;
  • chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling;
  • a change in the pattern or severity of migraine headaches;
  • nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • swelling in your hands, ankles, or feet;
  • a breast lump; or
  • symptoms of depression (sleep problems, weakness, tired feeling, mood changes).

Common side effects may include:

  • mild nausea (especially when you first start taking this medicine), vomiting, bloating, stomach cramps;
  • breast tenderness or swelling, nipple discharge;
  • freckles or darkening of facial skin, increased hair growth, loss of scalp hair;
  • changes in weight or appetite;
  • problems with contact lenses;
  • vaginal itching or discharge; or
  • changes in your menstrual periods, decreased sex drive.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Active ingredients: ethinyl estradiol/norethindrone

Select the most affordable brand or generic drug

Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.

Minastrin 24 Fe – Frequently asked Questions

Can Minastrin 24 Fe be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It’s wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Minastrin 24 Fe?

Some drugs can make birth control pills less effective, which may result in pregnancy. Other drugs may interact with Minastrin 24 Fe and norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Who should not take Minastrin 24 Fe?

Smoking can increase your risk of blood clots, stroke, or heart attack while taking birth control pills, especially if you are older than 35 years of age. Your risk increases the more you smoke. You should not take combination birth control pills such as Minastrin 24 Fe and norethindrone if you smoke and are older than 35 years of age.

This medication can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking birth control pills.

You should not take birth control pills if you have:

  • untreated or uncontrolled high blood pressure;

  • heart disease ;

  • a blood-clotting disorder or circulation problems;

  • problems with your eyes, kidneys or circulation caused by diabetes;

  • a history of hormone-related cancer such as breast or uterine cancer;

  • unusual vaginal bleeding that has not been checked by a doctor;

  • liver disease or liver cancer;

  • severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;

  • a history of jaundice caused by pregnancy or birth control pills; or

  • if you smoke and are over 35 years old.

To make sure birth control pills are safe for you, tell your doctor if you have:

  • high blood pressure, varicose veins;

  • high cholesterol or triglycerides, or if you are overweight;

  • a history of depression;

  • underactive thyroid;

  • gallbladder disease;

  • diabetes;

  • seizures or epilepsy;

  • a history of irregular menstrual cycles;

  • tuberculosis; or

  • a history of fibrocystic breast disease, lumps, nodules, or an abnormal mammogram.

The hormones in birth control pills can pass into breast milk and may harm a nursing baby. This medication may also slow breast milk production. Do not use if you are breast feeding a baby.

How should I take Minastrin 24 Fe?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You will take your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms or a spermicide, when you first start using this medication. Follow your doctor’s instructions.

Take one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You may get pregnant if you do not take one pill daily. Get your prescription refilled before you run out of pills completely.

The 28 day birth control pack contains seven “reminder” pills to keep you on your regular cycle. Your period will usually begin while you are using these reminder pills.

You may have breakthrough bleeding, especially during the first 3 months. Tell your doctor if this bleeding continues or is very heavy.

Use a back-up birth control if you are sick with severe vomiting or diarrhea.

If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medication for a short time. Any doctor or surgeon who treats you should know that you are using birth control pills.

While taking birth control pills, you will need to visit your doctor regularly.

Store at room temperature away from moisture and heat.

Can Minastrin 24 Fe be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Minastrin 24 Fe be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.



Following the study conducted by gmedication.com on Minastrin 24 Fe, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Minastrin 24 Fe. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Harshad Shah, MD Pharmacology

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