How long does it take for mobic to work?


Meloxicam, sold under the brand name Mobic, is a prescription drug used to treat pain and inflammation.

Meloxicam is prescribed to people who have tenderness, swelling, and pain caused by the inflammation of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid and idiopathic arthritis (JRA/JIA).

Meloxicam, a non-steroidal anti-inflammatory drug (NSAID), works by blocking the enzymes responsible for making prostaglandins, compounds that contribute to inflammation, especially joint inflammation.

By reducing the levels of prostaglandins, inflammation and other symptoms can be reduced.

The Food and Drug Administration (FDA) approved meloxicam in April 2000.

Boehringer Ingelheim Pharmaceuticals manufactures brand name Mobic, while other manufacturers make the generic form.

Meloxicam Warnings

If you have had an asthma attack, hives, or other allergic-like reactions after taking aspirin or any other NSAID, you should not use meloxicam.

Be sure to let your doctor know if you have had any of those problems in the past.

Never use meloxicam right before or after undergoing a heart surgery called a coronary artery bypass graft (CABG).

You also may not be a candidate for this drug if you’ve had ulcers, stomach bleeding, or severe kidney or liver problems.

Keep in mind that stomach ulcers and stomach bleeding can occur at any time during treatment with any NSAID, including meloxicam.

Be aware that stomach ulcers and bleeding can occur without warning symptoms, and may cause death.

The chance of developing a stomach ulcer or gastrointestinal bleeding increases with:

  • Taking blood thinning medications such as corticosteroids and anticoagulants
  • Longer use
  • Smoking
  • Older age
  • Having poor health
  • Drinking alcohol

Some people will have a warning of stomach bleeding in the form of burning stomach pain, black stools, or vomiting. If you experience any of these symptoms, call your doctor.

It’s also possible to sustain liver damage by taking NSAIDS like meloxicam.

Warning signs of liver damage include nausea, vomiting, fatigue, appetite loss, itching, jaundice (yellowing of the skin or eyes), and dark urine.

The medication can also result in fluid retention and swelling, which may contribute to heart failure.

Meloxicam is associated with an increased risk of heart attack, stroke, and high blood pressure. Long-term use may increase these risks.

To ensure your safety when taking this medicine, tell your doctor if you have any of the following conditions:

  • A history of heart attack, stroke, or blood clot
  • Heart disease, congestive heart failure, or high blood pressure
  • A history of stomach ulcers or bleeding
  • Liver or kidney disease
  • A seizure disorder like epilepsy
  • Asthma
  • Polyps in your nose
  • Tobacco smoking

You should speak to your doctor or pharmacist before using other cold, allergy, or pain medication, since drugs similar to meloxicam exist in many combination medicines.

If you’re taking meloxicam, carefully check the labels of other products you’re taking to see if they also contain an NSAID such as aspirin, ibuprofen, ketoprofen, or naproxen.

Taking too many NSAIDs can result in serious side effects, such as stomach ulcers, gastrointestinal bleeding, or cardiovascular problems.

Meloxicam and Pregnancy

Pregnant women are advised to avoid taking meloxicam, especially late in their pregnancy, unless their doctor has determined the potential benefits outweigh the potential risks to the fetus.

Tell your doctor if you are pregnant or plan to become pregnant while taking meloxicam, since it may impair your fertility and/or harm an unborn child.

It’s unknown whether the medication will pass into breast milk.

Nonetheless, the drug should be avoided while breastfeeding, so tell your doctor if you are breastfeeding or plan to do so.

Never give meloxicam to a child under two years of age without first speaking to your doctor.

Meloxicam for Dogs and Cats

Meloxicam can be prescribed for for dogs and cats to manage their pain and inflammation.

In addition to arthritis pain, meloxicam may be prescribed to dogs for pain from surgery, dental procedures, cancer, or injuries.

Because of the increased risk of side effects in cats, meloxicam has limited use in cats and is generally only prescribed as a single dose.

Side effects can include loss of appetite, vomiting, diarrhea, bleeding, and stomach ulcers.

What Are the Side Effects of Meloxicam (Mobic)?

Meloxicam (brand name Mobic) is a prescription nonsteroidal anti-inflammatory drug (NSAID). Mobic uses include: treating pain, inflammation, tenderness, and stiffness typically from rheumatoid arthritis or osteoarthritis.
Mobic was approved for use in the United States by the Food and Drug Administration (FDA) in 2000. Unlike opioid medications, meloxicam is not considered addictive. However, meloxicam is sometimes abused because it is mistakenly believed to have opioids in it. The medication does not induce euphoria, but it can lead to serious side effects, especially if taken excessively.

General Side Effects of Meloxicam

Some of the side effects
associated with meloxicam are usually not serious. However, you should consult with your healthcare provider if they do not go away on their own or if they are troublesome.

Some of these side effects that are more common include:

  • Diarrhea
  • Gas
  • Heartburn
  • Indigestion

Some of these side effects that are less frequent include:

  • Abnormal dreaming
  • Difficulty falling or staying asleep
  • Tiredness
  • Anxiety
  • Mild depression
  • Irritability
  • Confusion
  • Trouble concentrating
  • Appetite changes, especially an increased appetite
  • Stomach pain
  • Nausea/vomiting
  • Bloating
  • Constipation
  • Changes in vision
  • Itchy, burning, or dry eyes
  • Ringing in the ears, or tinnitus
  • Hearing loss
  • Dry mouth
  • Changes in taste
  • Unpleasant or unusual aftertaste
  • Rapid breathing
  • Tingling or pinprick sensations
  • Thinning hair

Harmful Side Effects of Meloxicam

While many of the side effects from taking meloxicam as prescribed will pass and are not serious, some can be dangerous. The risk of these side effects may go up if a person takes too much meloxicam or uses meloxicam for a long time.

If a person experiences any of the below symptoms, they should get emergency medical help by calling 911:

  • Chest pain
  • Shortness of breath
  • Slurred speech
  • Weakness on one side or part of the body

If a person experiences any of the below side effects, they should immediately stop taking meloxicam and contact their healthcare provider:

  • Stomach pain
  • Heartburn
  • Bloody vomit
  • Vomit with a coffee-ground appearance
  • Bloody, black, and/or tarry stools
  • Swelling (especially of the throat, tongue, lips, eyes, or face)
  • Trouble breathing or swallowing
  • Rash/blisters/itching
  • Fever
  • Hoarseness
  • Pale skin
  • Fast or irregular heartbeat
  • Nausea
  • Unexplained weight gain
  • Yellowed eyes or skin
  • Pain in the back or upper right part of the stomach
  • Discolored, bloody, or cloudy urine
  • Painful or difficult urination
  • Fatigue
  • Flu-like symptoms

Overdose Symptoms

It is possible to overdose on meloxicam. If a person takes too much meloxicam, call the poison control helpline at 1-800-222-1222. If they had a seizure, have difficulty breathing, collapsed, or cannot be woken up, call 911 immediately. Symptoms of an overdose include:

  • Loss of energy
  • Drowsiness
  • Nausea or vomiting
  • Bloody vomit
  • Vomit with a coffee-ground appearance
  • Stomach pain
  • Bloody, black, and/or tarry stools
  • Trouble breathing
  • Seizures
  • Coma

Meloxicam Can Cause Long-Term Harm

All medications have potential side effects. Long-term use of NSAIDs may increase the risk of stomach or intestinal bleeding, ulcers, or holes. Long-term use of non-aspirin NSAIDs may increase the risk of heart attack or stroke.

Bleeding, ulcers, or holes in the stomach or intestines can develop at any time during use of NSAIDs and can be fatal if untreated. People who are older, drink large amounts of alcohol, are in poor health, or are also taking other NSAIDs or certain other medications, as well as people who have been taking NSAIDs for a long time, may be at increased risk of developing these problems. These issues may happen without any warning signs, or they may present with heartburn, stomach pain, vomit with a coffee-ground appearance, bloody vomit, bloody stools and/or black and tarry stools. Contact a healthcare professional right away and stop taking meloxicam if you experience any of those symptoms.

Taking NSAIDs other than aspirin may increase a person’s risk of having a stroke or heart attack, which can be deadly. Long-term use of NSAIDs may increase this risk. People who have recently had a heart attack should not take an NSAID unless their healthcare provider specifically tells them to. Before starting an NSAID, let your health care provider know if you or anyone in your family has or has in the past had heart disease, a stroke, or a heart attack, as well as if you have or have in the past smoked, had high cholesterol, had high blood pressure, or had diabetes. Heart attack or stroke can occur without warning. Call 911 for emergency medical help if you have shortness of breath, chest pain, slurred speech, and/or weakness in one part or side of your body.

Insomnia is a potential adverse effect, as well. Insomnia can cause sleepiness during the day and lack of energy. This can cause serious problems, for instance if a person is driving when drowsy and gets into an accident. It can also lead to feeling depressed, anxious, or irritable, as well as cause difficulty focusing, learning, and remembering.

It is also possible to develop kidney damage from taking meloxicam. However, drug-induced kidney damage is often reversible if the drug causing it is stopped.

Meloxicam use can also lead to liver damage. Studies show that up to 7 percent of people who take meloxicam experience some elevated liver enzymes. This sometimes resolves on its own, even if the person is still taking meloxicam. Symptoms of liver damage may include fatigue, decreased appetite, nausea, yellowing of the skin or eyes, or dark urine.

Some people who take NSAIDs retain water, which can lead to swelling that is uncomfortable or even dangerous, as it can cause heart failure. Fluid retention may also lead to anemia. This swelling, also known as edema, is typically most noticeable in a person’s arms, hands, legs, ankles, and feet.

Women who are pregnant should consult their healthcare provider before beginning a prescription for meloxicam, and women taking meloxicam who think they may have become pregnant should let their healthcare provider know right away. Meloxicam may cause harm to the fetus.

Patients should make sure their healthcare provider is aware of all their past and current health conditions and any use of alcohol, tobacco, or other drugs, as well as all medications, vitamins, and supplements they are taking. This enables the provider to discuss with the patient the risks versus benefits of taking meloxicam, including the risks of possible interactions or adverse effects, and to decide if meloxicam is the right choice for that patient.

Get Help for Substance Abuse Involving Meloxicam or Other Drugs

Meloxicam is not addictive and does not cause feelings of euphoria, but some people may mistakenly believe it is an opioid since it is prescribed for pain. These individuals may try to get high from taking excessive amounts of this medication. The drug is sometimes diverted for illicit distribution, so it sometimes can be obtained through those routes.

People who struggle with substance use problems should seek help. If their addiction is not addressed, it can cause long-term harm to their bodies and minds. Treatment programs can help you overcome addiction. These programs typically include therapy to help people understand their addiction, to develop better coping mechanisms, and to find a healthy routine that does not involve drugs or alcohol.

About meloxicam

Type of medicine Non-steroidal anti-inflammatory drug (NSAID)
Used for Pain and inflammation in rheumatoid arthritis, ankylosing spondylitis and osteoarthritis
Available as Tablets and melt-in-the-mouth (orodispersible) tablets

Anti-inflammatory painkillers like meloxicam are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just ‘anti-inflammatories’. Meloxicam eases pain and swelling (inflammation) in long-term conditions like rheumatoid arthritis and ankylosing spondylitis, but it may also be used for a shorter period of time in osteoarthritis.

Meloxicam works by blocking the effect of natural chemicals called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Before taking meloxicam

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking meloxicam, it is important that your doctor or pharmacist knows:

  • If you have asthma or any other allergic disorder.
  • If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn’s disease or ulcerative colitis.
  • If you are pregnant, trying for a baby or breastfeeding.
  • If you have liver or kidney problems.
  • If you have a heart condition or a problem with your blood vessels or circulation.
  • If you have high blood pressure.
  • If you have high blood sugar or cholesterol levels.
  • If you are a smoker.
  • If you have ever had blood clotting problems.
  • If you have systemic lupus erythematosus. This is an inflammatory condition which is also called lupus or SLE.
  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as as herbal and complementary medicines.
  • If you have ever had an allergic reaction to any other NSAID (such as aspirin, ibuprofen, diclofenac, and indometacin), or to any other medicine.

How to take meloxicam tablets

  • Before you start taking meloxicam, read the manufacturer’s printed information leaflet from inside the pack. The leaflet will give you more information about the tablets and provide a full list of side-effects which you may experience from taking them.
  • Take meloxicam exactly as your doctor has told you to. The usual dose is one tablet a day. You will be prescribed either 7.5 mg tablets or 15 mg tablets.
  • Swallow the tablet whole with a drink of water.
  • Take each dose with a snack or just after eating a meal and drink plenty of water whilst on meloxicam.
  • If your doctor has prescribed melt-in-the-mouth (orodispersible) tablets:
    • Moisten your mouth first, taking a sip of water if needed.
    • Remove the tablet from the packaging, taking care not to moisten it.
    • Place the tablet on your tongue and allow it to dissolve slowly. This should take about five minutes.
    • After five minutes drink a large glass of water and swallow the dissolved tablet.
    • Do not chew the tablet or swallow it before it has dissolved.
  • Try to take your doses at the same time each day, as this will help you to remember to take them.
  • If you do forget to take a dose, take it as soon as you remember along with something to eat. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

Getting the most from your treatment

  • Your doctor will try to prescribe you the lowest dose for the shortest time to reduce the risk of side-effects. Your doctor may also want to prescribe another medicine for you to take along with meloxicam to protect your stomach from irritation.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories like meloxicam. If this happens to you, you should stop taking the tablets and see your doctor as soon as possible.
  • If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory like meloxicam.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

Can meloxicam cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common meloxicam side-effects What can I do if I experience this?
Feeling sick (nausea) or being sick (vomiting) Stick to simple foods. Drink plenty of liquid to replace any lost fluids
Loose, watery stools (diarrhoea) Stick to simple foods. Drink plenty of liquid to replace any lost fluids
Constipation Try to eat more foods that are high in fibre, such as fruits and vegetables, and drink plenty of water
Indigestion, stomach discomfort, wind Remember to take the tablets after a meal if you are not already doing so. If the discomfort continues, speak with your doctor
Other less common side-effects: headache, feeling dizzy or sleepy, nervousness, mood changes, difficulty sleeping, a spinning sensation (vertigo), and ringing noises (tinnitus) If any of these become troublesome, speak with your doctor

Important: if you experience any of the following uncommon but possibly serious symptoms, stop taking meloxicam and contact your doctor for advice straightaway:

  • If you have any breathing difficulties such as wheeze or breathlessness.
  • If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.
  • If you pass blood or black stools, vomit blood, or have tummy (abdominal) pains.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store meloxicam

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Keep the tablets in their original packaging.

Important information about all medicines

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

The pill most often prescribed for knee pain – acetaminophen – may not help at all, researchers reported Monday.

The new study of what works for arthritis pain in the knee came up with some surprising results. The most common treatments often may not help much, and even a placebo injection of salt water provides more pain relief than any pill.

The findings go against what many doctors have long believed, although they didn’t surprise veteran knee surgeons, who know pain relief varies greatly from one patient to another.

“All treatments except acetaminophen showed clinically significant improvement from baseline pain.”

Dr. Raveendhara Bannuru and colleagues at Tufts Medical Center near Boston looked at thousands of studies on various treatments for knee pain, from acetaminophen – the active ingredient in Tylenol – to ibuprofen to steroid injections.

Finding the scientific truths is tricky. There’s not much incentive for drug companies to test generic, over-the-counter drugs such as naproxen, and there’s also not much reason to test an injection of a steroid against a generic treatment such as hyaluronic acid, a kind of joint lubricant.

But the team came up with 137 studies covering 33,000 people that met some high standards – they’d been blinded, meaning the doctors didn’t know which treatment a patient actually got as they evaluated pain, stiffness and range of motion.

And most compared treatment to placebo – a dummy pill or dummy injection.

The results surprised them. “All treatments except acetaminophen showed clinically significant improvement from baseline pain,” they wrote in their report, published in the Annals of Internal Medicine.

“Contrary to popular belief, our results showed that celecoxib (a prescription drug sold under the brand name Celebrex) was not superior to acetaminophen.”

And a dummy injection of salt water worked better than any pill, although not better than injecting a steroid or lubricant.

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It might be due to a super placebo effect, or it could be that injecting any fluid into the knee, called viscosupplementation, provides at least temporary relief, Bannuru and colleagues said.

Either way, it’s a big issue for many people, and one that involves a whole lot of money, said Dr. Lisa Mandl of Weill Cornell Medical School in New York and Elena Losina of Brigham and Women’s Hospital in Boston.

“The global viscosupplementation market is estimated to be $2.5 billion by 2017, and the market for glucosamine is estimated to be $12 billion by 2020,” they wrote in an editorial.

“Almost 40 percent of the U.S. population older than 45 years has some degree of knee osteoarthritis and the estimated lifetime risk for knee (arthritis) is 14 percent,” they added.

The Tufts team did not look at alternative treatments such as glucosamine and chondroitin sulfate supplements. Both the American Board of Internal Medicine and the American Academy of Orthopedic Surgeons say they don’t work.

“Regardless, patients continue to demand these therapies,” Mandl and Losina noted.

“When we inject something into the knee, patients are going to improve for at least four weeks.”

This study may explain why. It is clearly difficult to tell which treatments work best for knee pain and relief may be highly subjective.

Dr. David Jevsevar, an orthopedic surgeon at Dartmouth Medical School and a chair of the Evidence-Based Quality and Value Committee of the American Academy of Orthopaedic Surgeons (AAOS), says it’s hard to judge knee arthritis pain because it comes and goes.

“Patients with knee osteoarthritis typically don’t have pain every day,” Jevsevar, who was not involved in the research, told NBC News.

“They have good days and bad days. If you do nothing, 60 percent of patients are going to get better because of the ebb and flow of osteoarthritis. When we inject something into the knee, patients are going to improve for at least four weeks.”

One finding that Jevsevar disagrees with was the Tufts team’s assertion that hyaluronic acid provides pain relief. The AAOS specifically recommends against it.

“It’s expensive,” Jevsevar said. “It can cost $700 to $1,000 an injection. That is a lot of money for something that doesn’t give you long-term benefit.” Jevsevar believes the Tufts analysis was flawed because it set too low a bar for measuring pain relief.

Instead, Jevsevar says his organization recommends taking things slowly and going with the cheapest and least invasive treatment first. That may mean weight loss – it really does work – and ice. Exercise can help, too, if it’s the right kind that doesn’t strain the knee. Swimming and cycling fit that bill. Physical therapy may also help.

Common knee surgery may not alleviate pain

Dec. 26, 201302:11

Next come over-the-counter treatments, including acetaminophen for many people, because it is non-toxic in recommended doses and doesn’t cause stomach bleeding like other drugs, such as aspirin and ibuprofen, can. Steroid injections come next, but not unless pain pills don’t do the trick.

“We believe that pharmacologic intervention is important for patients that can tolerate it,” Jevsevar said. “We believe that surgery is a last resort.”

At least one study has found that surgery is no better than medication and physical therapy for relieving the pain and stiffness of moderate or severe arthritis.

What is meloxicam?

Meloxicam (brand names Metacam® Loxicom®, OroCAM®, Rheumocam) is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever in dogs and cats. It is indicated for the treatment of osteoarthritis in dogs and cats. Meloxicam is also used to treat pain associated with surgery.

How do I give my pet meloxicam?

Meloxicam is available as an oral liquid, oral spray (spray not available in Canada), injection, or chewable tablets for dogs, but only as an oral liquid or injection for cats. It is also available in pill form (brand name Mobic®, Mobicox®) for human use, which your veterinarian may prescribe ‘off label’ or ‘extra-label’ for large dogs.

Many drugs are commonly prescribed for off label use in veterinary medicine. In these cases, follow your veterinarian’s directions and cautions very carefully.

Your veterinarian will administer the injectable version of the drug.

Before giving the oral liquid, shake the bottle well. Carefully measure the dose as directed by your veterinarian. Chewable tablets should be given as directed by your veterinarian.

Give meloxicam with food to reduce gastrointestinal side effects.

The oral spray is sprayed inside the cheek space. Your veterinarian will provide you with specific instructions for administering the medication.

This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

What if I miss giving my pet the medication?

If you miss giving your pet a dose, give the next dose as soon as you remember, but if it is closer than 12 hours before the next scheduled dose, either:

  1. skip the dose you missed, give it at the next scheduled time, and continue with the regular dosing schedule, OR
  2. give the missed dose and then wait the recommended interval before giving the next dose (continue giving it regularly at that new time).

Never give your pet two doses at once or give extra doses.

Are there any potential side effects?

Dogs: The most common side effect of meloxicam in dogs is gastrointestinal upset, including vomiting, soft stools, and lack of appetite.

Rarely, more serious adverse effects can occur. If there are changes in urination or yellowing of the skin (often noted on the inside of ear flaps), stop giving the medication and contact your veterinarian right away.

Cats: Meloxicam should be used with caution in cats. Cats with early undiagnosed kidney disease can suffer kidney damage with use of meloxicam, depending on the dose prescribed. Your veterinarian will carefully weigh the pros and cons of medicating your cat with meloxicam, and may order blood work and urinalysis to check your cat’s kidney function before prescribing meloxicam. Gastrointestinal upset, including vomiting, diarrhea, and lack of appetite are side effects sometimes seen in cats.

Never give meloxicam prescribed for one pet in your household to another pet without first consulting your veterinarian.

Any side effects that you observe should be reported to your veterinarian.

This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease.

Are there any risk factors for this medication?

Meloxicam should not be used in patients with allergies to aspirin or other NSAIDs.

It should not be used in:

  • pets with bloody stools or vomit
  • pets that have pre-existing kidney or liver conditions
  • pets that have loss of appetite
  • pets that are taking other NSAIDs (e.g., carprofen, etodolac, firocoxib, and aspirin) or corticosteroids (e.g., prednisone and dexamethasone)
  • pets that are dehydrated
  • breeding, pregnant, lactating animals
  • puppies younger than 6 months of age, or in kittens under 4 months of age

Meloxicam should be used with caution in:

  • cats (see above)
  • pets that have ulcers or have had them in the past
  • pets that have pre-existing heart conditions
  • pets that are old, weak, or frail
  • pets that have a bleeding disorder

Are there any drug interactions I should be aware of?

It is never a good idea to mix meloxicam with corticosteroids (such as prednisone, prednisolone) or other NSAID drugs.

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.

Is there any monitoring that needs to be done with this medication?

Annual blood testing before and after starting the use of meloxicam is recommended to monitor liver and kidney function primarily or to detect other signs consistent with gastrointestinal ulceration. It is common for your veterinarian to recommend or require annual blood tests to assess for effects on organ function.

How do I store meloxicam?

Store meloxicam at room temperature. Do not use after the expiration date stated on the bottle.

Keep out of reach of children.

What should I do in case of emergency?

If you suspect an overdose, or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

Contributors: Rania Gollakner, BS, DVM © Copyright 2018 LifeLearn Inc. Used and/or modified with permission under license.

How Long Does Meloxicam Stay in Your System? (Blood & More)

Meloxicam has a half-life of approximately 15 to 20 hours.
Women were shown to process the medication at faster rates than men, with a mean elimination half-life of 19.5 hours for women and 23.4 hours for men.

The drug can be detected on urine tests for up to five days after use.

Meloxicam Use

Meloxicam is a prescription medication sold under the brand name Mobic. It is a controlled substance and legal as long as you have a prescription for it.
The medication works to decrease proteins that cause inflammation. This reduces swelling and pain in the joints.

NSAIDs are often provided as an alternative to opioid-based painkillers for people who have been weaned off prescription painkillers. They are recommended as a safer option for this group when they experience pain in their muscles.

Side Effects

NSAIDs can cause several side effects, per Medical News Today. The following are possible side effects:

  • Headaches
  • Sore throat
  • Diarrhea
  • Constipation
  • Indigestion
  • Stomach pain
  • Drowsiness
  • Retention of fluid
  • Problems with circulation
  • Increase in blood pressure
  • Liver disease
  • Asthma
  • Frequent problems with a runny nose
  • Intolerance to fructose
  • Kidney disease

You should not take meloxicam if you are pregnant.

How Meloxicam Helps People With Arthritis

Meloxicam decreases pain, stiffness, and swelling associated with three different types of arthritis:

  • Rheumatoid arthritis: This is caused by the immune system. The body starts attacking ligaments and joints.
  • Juvenile rheumatoid arthritis: This is also caused by the immune system, but it presents before age 16.
  • Osteoarthritis: This form is associated with aging or normal wearing of the ligaments. This causes ligaments to thin and increases pain in the joints.

How Long Meloxicam Stays in Your Body

According to the Drug-Induced Liver Disease (Third Edition), this medication is often prescribed for use once daily because of its average half-life of 20 hours. After you take it, it turns into four metabolites, so your body can start reaping its benefits.

Your body mostly gets rid of meloxicam through feces and urine excretion. Some people may be taking additional medication for their arthritis or a different health condition, and this can affect the metabolism of the drug.

Data shows that meloxicam’s levels can remain stable in your blood for three to five days.

Maximum Dose

NSAIDs can cause complications in patients who are not in optimal health. You may want to switch to a different medication or use other methods to control pain stemming from arthritis.

DailyMed states that adults should not take more than 15 mg of meloxicam per day. Doctors are advised to give patients the lowest possible dose that is effective for their health issues.

Your sex, age, and renal health will influence how well you metabolize meloxicam.

Drug Tests

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You may be concerned about having meloxicam detected in drug screenings for employment or other reasons. Meloxicam is not known to make people feel intoxicated or high, and it is not traditionally tested for in drug screenings.

If you are taking meloxicam for legitimate medical reasons, tell the person administering the drug test and bring a copy of your prescription with you.

Detectability Windows

A 2002 study from Medscape shows that you can expect the following detectability windows when using meloxicam. The U.S. National Institutes of Health (2011, 2015) confirmed that results are still similar.


The concentration of meloxicam in your blood is highest nine to 11 hours after you take your dose, but it reaches its peak between 2.5 to 7 hours if you take the 15 mg dose of the medication. You can expect it to be detectable on blood tests for three to five days if your metabolism is normal.


Meloxicam can potentially be detected in urine-based drug tests for three to five days. Again, this is not a standard drug to test for most drug screenings.

Hair follicle testing

Healthline reports that a hair follicle test can detect the use of substances for up to 90 days. However, these tests look for common illicit drugs like cocaine, PCP, marijuana, methamphetamine, and other commonly misused drugs. In most cases, your place of employment or other entities will not be looking for NSAIDs.

Detox might be of interest to you if you want to stop using meloxicam to avoid side effects. However, places of employment will probably not be looking for meloxicam.

There is the potential for meloxicam to be misused and even abused, though rates of abuse would be incredibly low. Most often, such abuse would be a sign of a co-occurring mental health issue.


(July 2016) Meloxicam. MedlinePlus. Retrieved March 2019 from

Sample Opiate Withdrawal Management. Indian Health Service. Retrieved March 2019 from

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