Erythromycin topical gel usp

Contents

GENERIC NAME: ERYTHROMYCIN OINTMENT – TOPICAL (eh-rith-row-MY-sin)

BRAND NAME(S): Akne-Mycin

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to treat acne. It helps to reduce the number of pimples. Erythromycin is an antibiotic (macrolide-type). It works by stopping the growth of bacteria.

HOW TO USE: This medication is for use on the skin only. Clean and dry the affected area as directed. Then apply a thin layer of the medication on the skin and rub in gently, usually twice a day or as directed by your doctor. Wash your hands after use.Do not use large amounts or apply this more often or for a longer period than directed. Your condition will not clear faster, but the risk of side effects may be increased.Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day.Avoid getting this medication in your eyes or inside the nose or mouth. If this occurs, rinse thoroughly with water.Inform your doctor if your condition does not improve or if it worsens. It may take up to 3 months of regular use before the full benefits of this medication take effect.

SIDE EFFECTS: This medication may cause skin irritation, redness, or peeling, especially in the first few days as your body adjusts to the medication. Eye irritation may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Rarely, use of this medication may result in other types of skin infections (fungal or other bacterial infections). Contact your doctor if you notice any unusual skin irritation or other symptoms.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using erythromycin, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics (e.g., azithromycin, clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

Erythromycin eye ointment

What is this medicine?

ERYTHROMYCIN (er ith roe MYE sin) is a macrolide antibiotic. It is used to treat bacterial eye infections. It also prevents a certain type of eye infection that can occur in some babies.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Ilotycin, Romycin

What should I tell my health care provider before I take this medicine?

  • if you have an unusual or allergic reaction to erythromycin, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the tube, to your eye, fingertips, or any other surface. Squeeze the end of the tube to apply a thin layer of the ointment to the inside of the lower eyelid. Close the eye gently to spread the ointment. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use your medicine more often than directed. Finish the full course prescribed by your doctor or health care professional even if you think your condition is better. Do not stop using except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other eye products without telling your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve in 2 to 3 days.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • burning, stinging, or itching of the eyes or eyelids

  • changes in vision

  • redness, swelling, or pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Throw away any unused ointment after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Benzoyl peroxide and erythromycin topical

Generic Name: benzoyl peroxide and erythromycin topical (BEN zoe ill per OX ide and er ith roe MYE sin)
Brand Name: Benzamycin, Benzamycin Pak, Aktipak

Medically reviewed by Drugs.com on Jul 12, 2019 – Written by Cerner Multum

  • Overview
  • Side Effects
  • Dosage
  • Professional
  • Interactions
  • More

What is benzoyl peroxide and erythromycin topical?

Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect that allows excess oils and dirt to be easily washed away.

Erythromycin is an antibiotic. Erythromycin topical prevents bacteria from growing on the skin.

Benzoyl peroxide and erythromycin topical (for the skin) is a combination medicine used to treat acne.

Benzoyl peroxide and erythromycin topical may also be used for purposes not listed in this medication guide.

Important Information

benzoyl peroxide and erythromycin topical can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and get emergency medical help if you have: hives, itching; difficult breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.

Before taking this medicine

You should not use this medicine if you are allergic to benzoyl peroxide or erythromycin (Akne-Mycin, Eryderm, Erythrocin, Pediazole, and others).

FDA pregnancy category C. It is not known whether benzoyl peroxide and erythromycin topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether benzoyl peroxide and erythromycin topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use benzoyl peroxide and erythromycin topical?

Follow all directions on your prescription label. Do not use benzoyl peroxide and erythromycin topical in larger or smaller amounts or for longer than recommended.

Wash your hands before and after applying this medication.

Clean and dry the area to which you will apply the medication. Benzoyl peroxide and erythromycin topical is usually applied twice daily in the morning and evening. Follow your doctor’s directions.

Avoid getting this medicine in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. If it does get into any of these areas, wash with water. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin.

Do not cover the treated skin area after applying benzoyl peroxide and erythromycin topical. Doing so could cause too much medicine to be absorbed by the body and could be harmful.

It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and apply only the next regularly scheduled dose.

What happens if I overdose?

An overdose of benzoyl peroxide and erythromycin topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while taking benzoyl peroxide and erythromycin topical?

Do not use benzoyl peroxide and erythromycin topical on sunburned, windburned, dry, chapped, or irritated skin. It could make these conditions much worse. Also avoid using benzoyl peroxide and erythromycin topical on wounds or on areas of eczema. Wait until these conditions have healed before using this medicine.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Avoid using other medications on the areas you treat with benzoyl peroxide and erythromycin topical unless your doctor tells you to.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using benzoyl peroxide and erythromycin topical and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. This medication can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using sunscreen containing PABA on the same skin treated with benzoyl peroxide and erythromycin topical, or skin discoloration may occur.

Benzoyl peroxide can bleach hair or fabrics. Do not let this medicine come into contact with clothing, hair, or colored towels or bed linens.

Benzoyl peroxide and erythromycin topical side effects

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe redness, burning, stinging, or peeling of treated skin areas; or

  • diarrhea that is watery or bloody.

Common side effects may include:

  • mild burning or stinging;

  • itching or tingly feeling;

  • dryness or peeling of treated skin; or

  • redness or other irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benzoyl peroxide and erythromycin topical dosing information

Usual Adult Dose for Acne:

Apply to affected areas twice a day (morning and evening), or as directed by physician.

-This drug should be applied after skin is thoroughly washed, rinsed with warm water, and gently patted dry.
-Aktipak requires thorough mixing by the patient immediately before each use.
Use: For the topical treatment of acne vulgaris

Usual Pediatric Dose for Acne:

12 years or older: Apply to affected areas twice a day (morning and evening), or as directed by physician.

-This drug should be applied after skin is thoroughly washed, rinsed with warm water, and gently patted dry.
-Aktipak requires thorough mixing by the patient immediately before each use.
Use: For the topical treatment of acne vulgaris

What other drugs will affect benzoyl peroxide and erythromycin topical?

Do not use benzoyl peroxide and erythromycin topical during treatment with tretinoin (Retin-A). The combination could lead to severe skin irritation.

It is not likely that other drugs you take orally or inject will have an effect on topically applied benzoyl peroxide and erythromycin. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2018 Cerner Multum, Inc. Version: 2.02.

Medical Disclaimer

More about benzoyl peroxide / erythromycin topical

  • Side Effects
  • During Pregnancy
  • Dosage Information
  • Drug Interactions
  • Pricing & Coupons
  • En Español
  • 45 Reviews
  • Drug class: topical acne agents

Consumer resources

  • Erythromycin and Benzoyl Peroxide Gel
  • Erythromycin and Benzoyl Peroxide Gel Packets
  • Erythromycin and benzoyl peroxide Topical (Advanced Reading)

Other brands: Benzamycin, Benzamycin Pak

Professional resources

  • Erythromycin and Benzoyl Peroxide (Wolters Kluwer)
  • … +1 more

Related treatment guides

  • Acne

Erythromycin topical ointment

ERYTHROMYCIN (er ith roe MYE sin) is a macrolide antibiotic. It is used on the skin to treat acne.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Akne-mycin

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to erythromycin, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Wash the affected area with warm water and soap, rinse, and dry completely before applying. Apply a thin film to cover the affected area. Do not get this medicine in your eyes. If you do, rinse out with plenty of cool tap water. Use your doses at regular intervals. Do not use your medicine more often than directed. Use this medicine for the full course prescribed by your doctor or health care professional, even if you think your condition is better. Do not stop using except on your the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

  • other antibiotics

  • topical corticosteroids like dexamethasone, hydrocortisone and prednisolone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Tell your doctor or health care professional if your skin does not improve after 3 to 6 weeks of use. It can take 8 to 12 weeks of treatment to see the full effects of this medicine.

Do not wash your face more than 2 to 3 times a day. Frequent washing can make your skin very dry, scale or peel. Let your doctor or health care professional know if this happens. Do not use any soothing cream or ointment without advice.

You can use makeup while using this medicine. Only use water based products and apply lightly.

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • redness, swelling, pain

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dry, scaly skin

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Benzamycin

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 1/12/2018

Benzamycin (erythromycin 3%-benzoyl peroxide 5%) Topical Gel is a combination of an antibiotic and a medication that has an antibacterial effect and a mild drying effect used to treat acne. Benzamycin is available in generic form. Common side effects of Benzamycin include:

  • skin dryness,
  • burning,
  • stinging,
  • tingling,
  • itching,
  • redness, and
  • peeling of the top layer of skin.

Skin irritation, itching, burning, or redness may occur, especially at the start of treatment as your body adjusts to Benzamycin. Other side effects of Benzamycin include:

  • eye irritation and
  • skin discoloration.

Serious side effects of Benzamycin are not likely to occur. Seek emergency medical attention if you experience an allergic reaction to Benzamycin (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives).

Apply a dose of Benzamycin Topical Gel twice daily, morning and evening, or as directed by a physician, to affected areas after the skin is thoroughly washed, rinsed with warm water and gently patted dry. Avoid using harsh, abrasive, or irritating cleansers, perfumes, or cosmetics on the area being treated. Do not use other topical prescription or over-the-counter products on the same area at the same time unless directed to do so by your doctor. Benzamycin may interact with tretinoin (Retin-A). Other drugs may interact with Benzamycin topical. Tell your doctor all medications you use. During pregnancy, Benzamycin should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Benzamycin (erythromycin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Erythromycin / Benzoyl Peroxide?

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Amisulpride
  • Astemizole
  • Bepridil
  • Cisapride
  • Colchicine
  • Dihydroergotamine
  • Dronedarone
  • Eliglustat
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Flibanserin
  • Fluconazole
  • Grepafloxacin
  • Levomethadyl
  • Lomitapide
  • Lovastatin
  • Mesoridazine
  • Methylergonovine
  • Methysergide
  • Pimozide
  • Piperaquine
  • Posaconazole
  • Saquinavir
  • Simvastatin
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acalabrutinib
  • Acecainide
  • Afatinib
  • Ajmaline
  • Alfentanil
  • Amiodarone
  • Amitriptyline
  • Amoxapine
  • Anagrelide
  • Apomorphine
  • Aprepitant
  • Aprindine
  • Aripiprazole
  • Aripiprazole Lauroxil
  • Arsenic Trioxide
  • Ascorbic Acid
  • Asenapine
  • Atorvastatin
  • Azimilide
  • Azithromycin
  • Bedaquiline
  • Benzhydrocodone
  • Betrixaban
  • Bosutinib
  • Bretylium
  • Brexpiprazole
  • Brigatinib
  • Buprenorphine
  • Buserelin
  • Carbamazepine
  • Ceritinib
  • Cerivastatin
  • Chloral Hydrate
  • Chloroquine
  • Chlorpromazine
  • Cholera Vaccine, Live
  • Cilostazol
  • Ciprofloxacin
  • Citalopram
  • Clarithromycin
  • Clindamycin
  • Clofazimine
  • Clomipramine
  • Clozapine
  • Cobicistat
  • Cobimetinib
  • Codeine
  • Conivaptan
  • Crizotinib
  • Cyclobenzaprine
  • Dabigatran Etexilate
  • Dabrafenib
  • Darunavir
  • Dasatinib
  • Deflazacort
  • Degarelix
  • Delamanid
  • Desipramine
  • Deslorelin
  • Deutetrabenazine
  • Dibenzepin
  • Digoxin
  • Dihydrocodeine
  • Diltiazem
  • Disopyramide
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Donepezil
  • Doxepin
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Droperidol
  • Edoxaban
  • Efavirenz
  • Encainide
  • Encorafenib
  • Enflurane
  • Entrectinib
  • Eplerenone
  • Escitalopram
  • Fentanyl
  • Fingolimod
  • Flecainide
  • Fluoxetine
  • Fosaprepitant
  • Foscarnet
  • Fosnetupitant
  • Gatifloxacin
  • Gemifloxacin
  • Glasdegib
  • Gonadorelin
  • Goserelin
  • Granisetron
  • Halofantrine
  • Haloperidol
  • Halothane
  • Histrelin
  • Hydrocodone
  • Hydroquinidine
  • Hydroxychloroquine
  • Hydroxyzine
  • Ibrutinib
  • Ibutilide
  • Ifosfamide
  • Iloperidone
  • Imipramine
  • Inotuzumab Ozogamicin
  • Isoflurane
  • Isradipine
  • Ivabradine
  • Ivacaftor
  • Ivosidenib
  • Ketoconazole
  • Lapatinib
  • Lefamulin
  • Lenvatinib
  • Leuprolide
  • Levofloxacin
  • Lidoflazine
  • Lofexidine
  • Lopinavir
  • Lorcainide
  • Lumacaftor
  • Lumefantrine
  • Lurasidone
  • Macimorelin
  • Mefloquine
  • Meperidine
  • Methadone
  • Metronidazole
  • Mifepristone
  • Morphine
  • Morphine Sulfate Liposome
  • Moxifloxacin
  • Nafarelin
  • Naloxegol
  • Neratinib
  • Netupitant
  • Nilotinib
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Olaparib
  • Ondansetron
  • Osimertinib
  • Oxycodone
  • Paliperidone
  • Panobinostat
  • Pasireotide
  • Pazopanib
  • Pentamidine
  • Pentazocine
  • Pimavanserin
  • Pirmenol
  • Pitavastatin
  • Pitolisant
  • Pixantrone
  • Prajmaline
  • Probucol
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinidine
  • Quinine
  • Ranolazine
  • Ribociclib
  • Risperidone
  • Sematilide
  • Sertindole
  • Sertraline
  • Sevoflurane
  • Simeprevir
  • Siponimod
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Solifenacin
  • Sonidegib
  • Sorafenib
  • Sotalol
  • Spiramycin
  • Sufentanil
  • Sulfamethoxazole
  • Sulpiride
  • Sultopride
  • Sunitinib
  • Tacrolimus
  • Tadalafil
  • Tedisamil
  • Telaprevir
  • Telavancin
  • Telithromycin
  • Tetrabenazine
  • Tezacaftor
  • Theophylline
  • Tizanidine
  • Tolvaptan
  • Toremifene
  • Tramadol
  • Trazodone
  • Triclabendazole
  • Trifluoperazine
  • Trimethoprim
  • Trimipramine
  • Triptorelin
  • Troleandomycin
  • Vandetanib
  • Vardenafil
  • Vasopressin
  • Vemurafenib
  • Venetoclax
  • Verapamil
  • Vinblastine
  • Vincristine
  • Vincristine Sulfate Liposome
  • Vinflunine
  • Voriconazole
  • Warfarin
  • Zolmitriptan
  • Zotepine
  • Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alprazolam
  • Anisindione
  • Avanafil
  • Bexarotene
  • Budesonide
  • Buspirone
  • Cyclosporine
  • Diazepam
  • Dicumarol
  • Methylprednisolone
  • Midazolam
  • Phenprocoumon
  • Roflumilast
  • Sildenafil
  • Sirolimus
  • Suvorexant
  • Tolterodine
  • Triazolam
  • Trimetrexate
  • Valproic Acid
  • Zafirlukast

About erythromycin (with zinc) skin solution

Type of medicine Antibacterial
Used for Acne (spots)
Also called Zineryt® (erythromycin with zinc acetate)
Available as Topical skin solution

Acne is the common cause of spots. Most people with acne are aged between 12 and 25 years, but some older and younger people are affected too. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Tiny pores on your skin allow the sebum to come on to the surface of your skin. In acne, some of these pores become blocked, causing inflamed spots.

Antibiotics, like erythromycin, work by killing germs (bacteria) that can contribute to acne. They also reduce inflammation. Erythromycin usually works well to clear acne spots which are inflamed and any surrounding skin inflammation. Zineryt® skin solution also contains zinc acetate. This is thought to aid skin healing.

There are also other skin preparations available which contain erythromycin and are prescribed for acne. These gels/solutions combine erythromycin with a topical retinoid agent. See separate medicine leaflets called Isotretinoin gel for acne and Tretinoin for acne for more information about these products.

Erythromycin is also taken by mouth as a tablet, capsule or liquid medicine to treat infections – see the separate medicine leaflet called Erythromycin for more information about this.

Before using erythromycin (with zinc) skin solution

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using erythromycin solution it is important that your doctor or pharmacist knows:

  • If you are pregnant or breastfeeding. (Although erythromycin is not known to be harmful to an unborn baby, you should let your doctor know if you think you are pregnant.)
  • If you have ever had an allergic reaction to a medicine or a skin preparation.

How to use erythromycin (with zinc) skin solution

  • Before you start this treatment, read the manufacturer’s printed information leaflet from inside your pack. The leaflet will give you more information about erythromycin solution and how to use it.
  • Apply erythromycin solution exactly as your doctor tells you to. Wash and gently dry your skin, and then apply a thin layer of solution to the area where your spots occur. Use the solution twice a day, preferably in the morning and the evening. Wash your hands well after you have finished using it.
  • Do not use the solution on any areas of skin which are sunburnt or sore. Also, try to avoid getting it on the sensitive areas of your skin in or around your nostrils, your eyes and your mouth. If you have been using a preparation for your acne that has caused your skin to peel, allow your skin to recover for a few days before you start using the solution.
  • Zineryt® skin solution should be discarded eight weeks after being prepared by your pharmacist. There will be an expiry date written on the label to remind you.

Getting the most from your treatment

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. A full course of treatment may last for 3-6 months.
  • You may have to use erythromycin solution for 10-12 weeks before you notice the full benefit. If after this time you still do not think your skin has improved, discuss it with your doctor.
  • It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water may worsen acne. Do not wash more than you normally do. You cannot clean off blackheads. The black tip of a blackhead is actually a skin pigment and cannot be removed by cleaning or scrubbing.
  • You may use make-up and moisturisers, but wait until your face has dried completely after using the solution, before you apply them.
  • During your treatment your doctor may ask you to use another skin preparation for a short while from time to time. It is important you follow your doctor’s advice, as it will help prevent your spots from becoming resistant to treatment.
  • You can use Zineryt® skin solution when you are pregnant or breastfeeding. If you are breastfeeding you should not use the solution on the chest area.

Can using erythromycin (with zinc) skin solution cause problems?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with Zineryt® skin solution. You will find a full list in the manufacturer’s information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of using a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects What can I do if I experience this?
Skin irritation or itching, redness, dry skin Take care not to apply too much solution. It may also help to use a fragrance-free, water-based moisturising cream. Do not use ointments or oil-rich creams, as these may clog pores

If you experience any other symptoms which you think may be due to this preparation, speak with your doctor or pharmacist.

How to store erythromycin (with zinc) skin solution

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Zineryt® solution should only be used for eight weeks after it has been made up by your pharmacy. Check the expiry date on the bottle and do not use it after this date.

Important information about all medicines

This preparation is for external use only. If someone swallows some of it, contact your doctor or pharmacist for advice or go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.

If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

This preparation is for you. Never give it to other people, even if their condition appears to be the same as yours.

Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Acne is one of the most common skin-disease affecting people across the globe, irrespective of gender, age or race.

Acne can be treated in a number of ways which have been commonly recognized worldwide.

Antibiotics like Clindamycin and Erythromycin are some of the most preferred antibiotics administered in cases of acne outbreaks.

Please feel free to use the Table of Contents below to jump to the relevant section

What is Erythromycin?

Erythromycin is an antibiotic that is used to treat certain kinds of bacterial infections that are sensitive to erythromycin.

It is also known as a macrolide antibiotic. It is effective in curing infections spread to various body parts and is not just limited to the skin.

Other uses of erythromycin as a medication (when taken orally) include:

  • It is used in cases of stomach and intestinal stoppage and it stimulates the movement of bowels.
  • It is used to treat certain infections caused by bacteria such as bronchitis, diphtheria, pneumonia, whooping cough, etc
  • It treats infection of the ear, lungs and urinary tract.

How does Erythromycin treat acne?

Erythromycin in its topical form is used to treat acne. It kills the bacteria and prevents their growth thereby preventing acne breakouts.

It is specifically effective against inflammatory acne breakouts.

However, it is most effective when used in combination, especially with Clindamycin and Benzoyl Peroxide.

Both medications are more effective when used together as compared to the use of either by themselves.

How to use Erythromycin?

A thin layer of the Erythromycin gel should be applied on the spot twice a day after the face has been cleaned and dried.

It should be used at the same time each day unless specifically told otherwise by the doctor.

Topical application twice a day will not lead to any absorption. In order to get the most benefits, it should be used for the complete duration of the prescription.

If a white film appears on your skin after the gel has been applied, then you have applied too much of it.

If there is no improvement after 6 or 8 weeks of its use or if the condition grows worse, the treatment should be discontinued and the physician should be consulted.

How much to use?

The dose is subject specific and is based on age, gender, medical condition and use of certain interacting medicines.

However, 2% Erythromycin is generally considered effective for acne outbreaks.

When used in form of a gel, 30 gm and 60 gm tubes are available with the weight of 2% Erythromycin each, costing 21.63$ and 39.77$ respectively.

The gel can take a few weeks before the benefit is seen.

When used in a solution form, 60 ml formulation having a concentration of 2% Erythromycin is available at the price of 24.63$.

How to Store?

Erythromycin topical is for external use only and should be kept away from the eyes, nose, mouth or lips. It should be kept in a cool dry place, away from heat and excess moisture.

Erythromycin gel or solution contains 66% to 92% alcohol.

According to the Resource Conservation and Recovery Act (RCRA) by the EPA any product containing more than 24% alcohol is D-listed and must be disposed off as hazardous pharmaceutical waste if not used completely.

Its disposal must, therefore, be discussed with the doctor or chemist or the concerned authority.

Possible Side Effects of Erythromycin

Here are some possible side effects of Erythromycin

  • Can produce local erythema.
  • Peeling and dryness of the skin along with itching.
  • Burning of the area on which it is applied.
  • The occasional oiliness of the skin.
  • Tenderness of skin.
  • Irritation of the eyes.
  • Generalized urticaria. (skin rash making the skin pale and red)
  • Safety and effectiveness in pediatric patients have not been established.

Precaution while using

Some key precautions while using Erythromycin include:

  • It is for topical use only. It is not for ophthalmic use.
  • It should be used only when and as advised by the doctor.
  • It is for external use only and must be kept away from the eyes, mouth, nose and all mucous membranes.
  • No other topical acne medication should be used at the same time unless otherwise advised by the doctor.
  • Any signs of local adverse reaction should be reported to the doctor.
  • It should be used for no other disorder than the one for which it has been prescribed.
  • The doctor must be informed if you are allergic to any macrolide bacteria.
  • The doctor must be informed about all prescriptive and non-prescriptive medications, vitamins and herbal products you are using including any other topical medication for acne.
  • The doctor will not prescribe this medicine to you if you have recently had sunburn or have skin problems like rosacea or eczema.
  • It might make your skin sensitive to sunlight, therefore, avoid any unnecessary exposure to the Sun and when unavoidable, use protective covering.
  • The doctor must be informed if you are pregnant, plan to become pregnant or are breastfeeding. In case you get pregnant while using the product, the doctor must be informed.(though it is not proved to be particularly harmful)
  • Ask your doctor to recommend a moisturizer to keep your skin soft during treatment.

Popular Erythromycin Brands

  • Benzamycin Pak: It is flammable and must not be kept near an open flame.
  • Theramycin
  • Erythra-Derm
  • Ery-Sol

Customer Reviews of Erythromycin for Acne

Most consumers were happy with the result of this medication through a few of them still believed that the treatment is not particularly permanent as the acne seemed to recur some years after the medication was started.

We reviewed the responses of online consumers to see what they think about the product. Here is the summary of the review:

What consumers liked about Erythromycin

Quickly and effective: Many consumers have seen its result to be quick and effective. It clears up to 50% of acne in just 6 weeks.

No Initial breakouts: Unlike other acne treating products, this does not cause any initial acne breakouts.

Most consumers were happy that they did not have to face the initial worsening of their skin before the healing process started.

Given Glowy skin: A lot of consumers witnessed not only he complete healing of acne, but also their skin became more glowy, soft, fresh and clear.

What consumers dislike about Erythromycin

Can Develop resistance: A few consumers suggested that though it worked for them initially, with time their skin developed resistance against erythromycin and it stopped working and had no effect on their acne.

Has a Stingy smell: Some consumers complained of acid like the stingy smell at the time of application.

Its application also resulted in peeling residue in the morning.

May lead to Hyper-pigmentation: Some consumers complained of pigmentation on their skin after the application or use of erythromycin.

They developed red and black patches which caused scarring of the skin.

Summary

Erythromycin is one of the most widely used antibiotics for treating acne breakout.

In spite of the fact that the skin might develop resistance, later on, it has proven to be very time effective and has gone a step further in improving the texture of the skin and making it glow.

Most consumers recommend it as being very helpful even in cases where other medications have been of no use.

When taken according to the doctor’s advice and in the correct dosage it can work wonders for your skin and is definitely worth a try.

Our articles are written by writers with a deep domain understanding of the topic and usually hold Bachelors / Masters degrees. The articles are peer-reviewed before being uploaded on the website. Our writers spend 10s of hours researching and writing articles which are factual and comprehensive. Check out about our team in About Us section.

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