Diclofenac sodium eye drops

Voltaren Ophthalmic

SIDE EFFECTS

Ocular

Transient burning and stinging were reported in approximately 15% of patients across studies with the use of Voltaren Ophthalmic. In cataract surgery studies, keratitis was reported in up to 28% of patients receiving Voltaren Ophthalmic, although in many of these cases keratitis was initially noted prior to the initiation of treatment. Elevated intraocular pressure following cataract surgery was reported in approximately 15% of patients undergoing cataract surgery. Lacrimation complaints were reported in approximately 30% of case studies undergoing incisional refractive surgery. The following adverse reactions were reported in approximately 10% or less of the patients: abnormal vision, acute elevated IOP, blurred vision, conjunctivitis, corneal deposits, corneal edema, corneal opacity, corneal lesions, discharge, eyelid swelling, eye pain, injection (redness), iritis, irritation, itching, lacrimation disorder, and ocular allergy.

Systemic

The following adverse reactions were reported in 3% or less of the patients: abdominal pain, asthenia, chills, dizziness, facial edema, fever, headache, insomnia, nausea, pain, rhinitis, viral infection, and vomiting.

Clinical Practice

The following reactions have been identified during postmarketing use of topical diclofenac sodium ophthalmic solution, 0.1% in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. The reactions, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to topical diclofenac sodium ophthalmic solution, 0.1%, or a combination of these factors, include corneal erosion, corneal infiltrates, corneal perforation, corneal thinning, corneal ulceration, and epithelial breakdown (see PRECAUTIONS, General).

Read the entire FDA prescribing information for Voltaren Ophthalmic (Diclofenac Sodium Ophthalmic Solution)

About diclofenac eye drops

Type of medicine A non-steroidal anti-inflammatory eye drop
Used for Before an operation, to help prevent the pupil becoming smaller during surgery; after eye surgery or laser treatment, to ease pain and discomfort; allergic eye conditions such as hay fever
Also called Voltarol® Ophtha
Available as Eye drops (multi-dose) and single-dose units

Diclofenac belongs to a group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). You will be prescribed the eye drops for one of the following reasons.

  • Diclofenac eye drops are used short-term to relieve pain and swelling which can be caused by eye surgery (for example, cataract surgery and laser surgery).
  • Diclofenac eye drops are used during eye surgery, to prevent the pupil of the eye from becoming smaller.
  • Diclofenac eye drops are prescribed to relieve eye symptoms of seasonal allergies such as hay fever.

Before using diclofenac eye drops

To make sure this is the right treatment for you, before you start using the eye drops it is important that your doctor knows:

  • If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you know you are allergic to an NSAID such as naproxen or ibuprofen, or if you have ever had a bad reaction to aspirin.
  • If you have a tendency to bleed easily.
  • If you know you have an eye infection.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicines or using any other eye drops. This includes any medicines or creams which are available to buy without a prescription, as well as herbal and complementary medicines.

How to use diclofenac eye drops

Before you start the treatment, read the manufacturer’s printed information leaflet from inside the pack. It will give you more information about the eye drops and will also provide you with a full list of the side-effects which you could experience from using them.

How to use eye drops

  1. First wash your hands.
  2. Remove the cap (or the tip of the unit if you are using a single-dose unit).
  3. Tilt your head back a little and pull the lower lid of your eye downwards to form a pocket.
  4. Hold the bottle (or single-dose unit) upside down near to your eye. Try not to touch your eye as you do this.
  5. Gently apply enough pressure to release one drop into your eye.
  6. Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.
  7. Repeat the process in your other eye if you have been told to use the drops in both eyes.
  8. Replace the cap (or if you are using the single-dose unit, throw it away).

Getting the most from your treatment

  • Use the drops exactly as your doctor tells you to. As a guide, the usual dose is one drop four times a day. If you are having eye surgery, you will probably be asked to start using the drops before the procedure, and then to continue to use them for a few days afterwards. If you are using the drops for hay fever, continue to use them for as long as needed.
  • Take care not to touch your eye, fingers, or any other surface with the dropper of the bottle. This could contaminate the drops left in the bottle.
  • If your doctor has recommended you use another eye preparation as well as these drops, then leave at least five minutes between putting in diclofenac drops and the other preparation.
  • Remember to use the drops at regular intervals and try not to miss any doses. If you do forget, use them as soon as you remember (unless it is nearly time for your next dose, in which case just use the drops when they are next due). Do not ‘double up’ to make up for forgetting to use the drops.
  • Try to keep any appointments which have been booked for you with the eye clinic. This is so your doctor can check on your progress.
  • There is a preservative present in bottles of diclofenac eye drops which can affect soft contact lenses, so do not wear contact lenses while you are using the drops unless your doctor has advised you otherwise. Following eye surgery, your doctor will recommend you use glasses for a time if you normally wear contact lenses.
  • When first put in, eye drops can make your eyes water and may sometimes cause blurred vision. If this happens, it should quickly clear. Make sure you can see clearly again before you drive, or before using tools or machines.

Can diclofenac eye drops cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with diclofenac. You will find a full list in the manufacturer’s information leaflet supplied with the eye drops. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common diclofenac eye drop side-effects What can I do if I experience this?
Eye pain, eye irritation This can happen soon after applying the drops. It should pass quickly

Bottles of eye drops contain preservatives which some people can develop an allergic reaction to. If your eye becomes red or inflamed after using the drops, contact your doctor for advice.

If you experience any other symptoms which you think may be due to the eye drops, speak with a doctor or pharmacist.

How to store diclofenac eye drops

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Bottles of eye drops only keep for four weeks once the bottle has been opened. Dispose of the bottle after this time, even if there is still some solution remaining. This will help prevent the risk of eye infections. Single-dose units do not contain a preservative and should be disposed of immediately after use.

Important information about all medicines

This preparation is for use in the eyes only. If someone swallows some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are using.

If you buy any medicines check with a pharmacist that they are suitable to take with your other medicines.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Financial disclosure: Michael Stewart has received an honorarium for attending a one-day pharmacy advisory panel on treating dry eye in community pharmacy, hosted by Thea Pharmaceuticals Ltd.

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