Cbd diabetes type 2


Ten Questions Answered on CBD Oil and Diabetes

As marijuana is becoming increasingly legal and socially acceptable, its related hemp byproducts are getting a lot of attention for potential health benefits. CBD oil is first on that list. But should you use it if you have diabetes?

To get answers, we queried both a medical expert and a diabetes patient experienced with using CBD oil.

What is CBD Oil and How Do You Use It?

Cannabidiol, better known as CBD oil, is extracted from the cannabis plant, and diluted with a “carrier oil” like coconut or hemp seed oil.

CBD is one of the many chemicals known as “cannabinoids” found in the cannabis plant, that appear to bind to receptors in the brain to produce certain effects. But this one does not contain the best-known cannabinoid, tetrahydrocannabinol (THC), which causes the “high” people feel after using marijuana.

CBD oil does not produce a high, but it is credited with alleviating symptoms of a number of ailments, including chronic pain, anxiety and depression.

It should not be smoked. Rather, it is edible and can be added to food. It can also be used topically on the skin. But it’s most often taken in pure oil form by simply placing the desired quantity of drops under your tongue using the dropper, and holding it there for a minimum of 60 seconds — to allow for absorption via the blood vessels. Once 60 seconds has passed, you swallow the CBD oil.

How much to take depends on the condition you’re hoping to treat, but generally runs between 2.5 – 20mg per day, according to most product recommendations.

CBD Oil and Diabetes

Diabetes is an inflammatory condition and CBD does have anti-inflammatory properties. In research, CBD has shown promise in reducing insulin resistance and moderating blood sugars for people with type 2 not taking insulin.

When we queried leaders in diabetes education to learn more about CBD oil and diabetes, we were immediately referred to Emily Kyle, a Registered Dietitian Nutritionist (RDN) and Holistic Cannabis Practitioner based in upstate New York. While not a diabetes expert per se, Kyle has become well-known among healthcare providers as an expert on the overall health effects of cannabis.

Emily Kyle, Registered Dietitian Nutritionist

We asked her five key questions on CBD oil as it relates to diabetes:

DM) CBD oil is becoming increasingly popular as a sleep aid / pain reliever / treatment for anxiety and depression. Are there any concerns about using it when you have diabetes?

EK) Just like any other over-the-counter supplement or medication, there are obvious concerns when using CBD oil if you have type 1, type 2, or gestational diabetes. Concerns can range from the type and quality of the product being used to various potential side effects that may occur as a result.

The biggest concern lies in the possibility of a cannabinoid-drug interaction for those who are taking prescribed medication and/or insulin to manage their diabetes. Researchers believe that “it is possible that the endocannabinoid system buffers insulin sensitivity rather than strictly inhibiting it.”

There’s a lack of clinical evidence to provide guidelines one way or another of the safety and efficacy of the cannabinoid CBD itself. Additionally, CBD is just one of hundreds of cannabinoids, and it is unclear whether other cannabinoids such as CBN or THC, which could be found within a CBD oil product, may have a direct impact on those with diabetes as well.

Does it have any direct effects on blood sugar?

Unfortunately, clinical studies in humans on the direct effect of CBD oil on blood sugar is lacking, likely due to the illegal status of marijuana which is currently seen as a schedule 1 drug in the eyes of the Federal Government.

What we do know is that the body’s endocannabinoid system plays an integral part in the regulation of energy metabolism, which is important to know for those who are living with diabetes. Emerging data suggests that “the endocannabinoid system sets the sensitivity of the insulin response in adipocytes.” This means that the endocannabinoid system plays an important role in how the body responds to insulin, increasing or decreasing insulin sensitivity. This is critically important for those who are taking insulin because it could mean that their blood sugars could rise or fall unexpectedly, making tight control more difficult to achieve.

Anecdotally, I have had clients who exhibit completely different response reactions to CBD oil use. One client told me it dramatically decreased their blood sugar within a matter of minutes, which is potentially very dangerous. Other clients notice no effect on blood sugar at all. This is attributed to the uniqueness of each person’s endocannabinoid system and their personal endocannabinoid tone.

What’s the best CBD oil to choose if you have diabetes?

The best CBD oil to choose if you have diabetes is one that has been produced by a reputable company that has also been verified by a third-party lab testing company to ensure that what is stated on the label is accurate and true. At this time CBD is an unregulated market and several studies have shown that several CBD oil products are misleading to consumers by either not containing what was promised, or containing additional ingredients that were not disclosed.

Additionally, I always recommend individuals stay away from and added ingredients, artificial flavorings, artificial dyes, added sugars or other ingredients such as melatonin.

What about CBD gummies that also contain sugar? Are they still an option for PWDs (people with diabetes), or do you know of any brands with no carb effect?

Regardless of whether you have diabetes or not, if we are truly using CBD for health promoting purposes and/or preventative wellness, it is counter-intuitive to combine that with refined sugar, artificial dyes, and artificial flavorings.

Instead, I encourage people to make their own CBD gummies at home with whole-food ingredients such as fruit and vegetable purees and quality CBD oil extract or concentrate. For a quick and easy tutorial on how to make your own CBD Gummies at home using real fruit and vegetable purees with no added sugar, check out my guide to making your own homemade CBD gummies.

What should PWDs consider when deciding whether or not to try CBD oil?

If you are unsure about how to begin to use CBD oil with a condition like diabetes and want to do so safely, consider reaching out to a Holistic Cannabis Practitioner or other trained healthcare professional for cannabis counseling. (Yes, that’s a thing!)

Using CBD Oil with Type 1 Diabetes

We also spoke with Rob Howe, a Texas-based former pro basketball player-turned-diabetes-advocate who was diagnosed with type 1 diabetes as a teenager in 2006. He runs a nonprofit called “Diabetics Doing Things.” In recent years, he’s become a proponent for use of CBD oil.

We also asked him five key questions on the topic:

DM) How do you personally use CBD oil? Do you ingest it, or put it on your skin?

RH) I actually do both, but my primary form is by oral capsules. I usually take one 30mg pill every morning or I mix 30mg of tincture (liquid) into my coffee in the morning. I’ve used it as a topical cream as well, but mostly on sore joints. I find that I get more of a whole body effect by taking CBD orally.

You’ve mentioned that CBD oil “evens you out”… What does that mean? What are the actual effects on your body?

Good question! The best example I can give is that I’m a very deep sleeper, and tend to have a tough time getting going in the mornings. CBD keeps me more balanced, meaning I can wake up easier, get warmed up for sports/fitness easier, recover from workouts quicker, get ready for bed easier, etc. In terms of measurable effects, I would say my soreness is reduced after workouts, I have more time in deep sleep on my sleep tracker, and I’m in a better mood as a result of both.

Have you noticed any impact on your diabetes specifically?

As far as I can tell, I haven’t seen any direct impact on my blood sugars as a result of taking CBD as it is available over the counter or online. That’s just my experience. However, the ability to get more exercise without pain and get better sleep have indirect impact on my diabetes, so I think that tips the scales in the favor of ‘CBD does impact my diabetes positively.’

Does your endocrinologist or CDE (certified diabetes educator) know of, or have any thoughts on, your use of CBD oil?

My endo sort of rolls her eyes at me because of my pursuit to be a hyper-optimized human, so to her CBD is just another of the latest and greatest health trends that I’m into. She of course asked me to be mindful when I started taking it, and was happy to hear of my positive outcomes regarding holistic health and wellness even though I told her my diabetes had not been directly impacted.

In your opinion, what’s the best CBD oil for a person with diabetes?

I use GreenHelix CBD oil, specifically the GreenHelix Recovery and GreenHelix Super Pure products. They help with joint pain relief and ease some of my social anxiety and depression symptoms. The company also has a CBD oil-based sleep product and a skincare cream that I haven’t tried yet, but look interesting.

This article has been medically reviewed by , PhD, MSN, RN, IBCLC, AHN-BC, CHT, on 8/23/2019.

What is the best dosage of CBD for diabetes related symptoms?

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    Concerning CBD and diabetes related symptoms the questions asked regularly are:

    How much CBD should I take for diabetes related symptoms?
    What is the best CBD oil for diabetes related symptoms?
    How does CBD work to effect diabetes related symptoms?
    What are the side effects of CBD?

    In this FAQ, we will answer the above questions, and walk you through the basics of using Green Flower Botanical’s CBD products.

  1. The FDA Guidelines (legal stuff)
  2. Will CBD Help Diabetes Related Symptoms? – The Current Research
  3. Finding Your Minimum Effective Dose – How Much CBD Do I Take And How Often?
  4. How To Determine Dosage Based On Type of Product
  5. Sublingual Oils vs Vapor – Which Are Best?
  6. CBD Side Effects and Drug Interactions

1. The FDA Guidelines Concerning The Use Of CBD For Diabetes Related Symptoms

(Let’s get the legal stuff out of the way first)

It is important to note that CBD products are not approved by FDA for the diagnosis, cure, mitigation, treatment, or prevention of any disease. We are restricted from making any claims about the efficacy of our specific CBD products to treat or cure any disease or medical condition including diabetes.

None of the products or information made available to the public is intended to be a treatment protocol for any disease state, but rather are offered to provide information and choices regarding nutritional support for various health concerns. None of the information presented is intended to be an enticement to purchase and should not be construed as medical advice or instruction. The FDA would want us to remind you: You should always seek the advice of a physician before adding nutritional supplements to your diet.

2. Will CBD Help with Diabetes? – What the Current Research Says

Cannabidinoids are components of the Cannabis plant that have been shown capable of suppressing inflammation and various aspects of cell-mediated immunity. Scientists now report that treatment with cannabidiol (CBD) reduces the incidence of diabetes significantly in NOD mice; from an incidence of 86% in non-treated control mice to an incidence of 30% in CBD-treated mice. The results in the same study show that CBD is able to inhibit and delay destructive insulitis and inflammatory TH-1-associated cytokine production in NOD mice. This leads to a decrease in the incidence of diabetes probably through an immunomodulatory mechanism.

Furthermore, CBD can create endogenous precursor cells in the pancreas to slowly give rise to increased beta cell mass and volume in the early stages of Type 1 diabetes, thereby maintaining normal blood sugar levels. CBD has been shown to decrease the need for insulin in type 1 diabetes by a significant number – 58%. CBD has also successfully reversed type 2 diabetes; it causes glucose breakdown, lipid breakdown, and increases insulin sensitivity. According to Raphael Mechoulam, PhD., Professor of Medical Chemistry and Natural Products, at Hebrew University in Jerusalem, and world renown for his expertise on the Cannabis Sativa plant, “CBD did not only prevent the onset (of diabetes), it blocked the development of diabetes.”

Recent epidemiologic studies have established lower prevalence rates of obesity and diabetes mellitus among cannabis users compared to non-users, suggesting a relationship between cannabinoids and peripheral metabolic processes. One study involving 4657 adults from the National Health and Nutrition Examination Survey from 2005 to 2010 sought out to establish these facts. Of the participants, 579 were current marijuana users and 1975 were past users. The outcome showed that current marijuana users recorded 16% lower fasting insulin levels and 17% lower HOMA-IR compared to non and past users. The scientists concluded that cannabis use was involved in the lower levels of fasting insulin and HOMA-IR, and smaller waist circumferences observed in the subjects.

For more information on the studies relating to the use of CBD for diabetes, go to this page.

3. Finding Your Minimum Effective Dose: How Much CBD Do I Take And How Often?

Due to FDA regulations we cannot give specific advice on how to use CBD for a particular condition such as diabetes. Fortunately though, the process to find a minimum effective dose of CBD for any condition, is very simple. The key to finding the most effective dosage is by using what is called, a Stepwise Dosing procedure.

Stepwise Dosing is a process by which you first establish a baseline dosage, then adjust the dosage incrementally over a set period of time (typically 3 days) until you find your effective dose.

It is important to recognize that everyone responds a little differently to CBD so there is no set dose for everyone or every condition. By following a stepwise dosing procedure you can find the most effective dosage of CBD for you.

The Stepwise Dosing Procedure

Start Low and Go Slow: The first step to finding your minimum effective dose is to establish a baseline dosage. Since many people report good results with CBD at low doses, we suggest you start with a minimal dose and slowly increase the dosage until you find results. Start with a small baseline dosage between 2-5mg, 2X or 3x daily (6-10mg total).

  1. Maintain your baseline dosage for 7 days taking note of how the CBD interacts with your body.
  2. After the initial 7 days of your baseline CBD dosage, if you are not receiving the benefit you need, then increase the daily dosage by 1-2mg every 3 days until you find the dosage that works best for you.
  3. Once you have determined your minimum effective dose you may wish to decrease your dosage by one step to see if you can maintain the benefits at a slightly lower dosage.

Important Note: Typically, people decide to try CBD because of a specific condition, only to find it helps other areas of their body as well. Remember, your endocannabinoid system runs throughout the entire body at a cellular and sub-cellular level. CBD is a whole-body compound. When you start taking CBD for the first time, pay attention to everything going on in your body. Do not be surprised if you find various benefits from your dosage.

About Sleep: Often times, certain conditions or side-effects from medication can create insomnia. Sleep is essential to the bodies healing and recovery process. If sleep deprivation is an issue, you may want to consider weighting your dosage heavier at night to assist with a more sound sleep.

Establishing A Baseline Dosage Based On Weight

If you feel you need a higher dosage as a starting point we have created the following chart to assist you. This chart is submitted as a suggestive guide only and is not meant to take the place of a qualified physician.

4. How To Determine Dosage Based On A Specific Product

Once you have established a minimum effective dose using the stepwise dosing procedure, the following chart will help you determine which sublingual oil potency will best meet your daily dosage requirement. To find the best product match for your dosage simply match your daily dosage to the row on the chart labeled “30 Day Supply in Bottle”. For example: If you need 15mg CBD daily then according to the chart you would need a 450mg product. The chart also acts as a guide to how to use the glass dropper to measure out CBD in milligrams.

Dosing With CBD Vapor

Once you have established a minimum effective dose using the stepwise dosing procedure above, the following chart will help you determine how to measure milligrams of CBD using either our 250mg or 500mg CBD Vapor Cartridges. As an example, if you needed an 8mg dosage, the chart shows several options to dial-in that dosage using a vape pen. To get 8mg total CBD you could choose to take four 4-second puffs or you could choose two 8-second puffs. A puff is measured by drawing on the vape and counting seconds as 1-1000, 2-1000, etc. Keep in mind everyone will draw their puff a little differently so the values on this chart are only best approximations.

5. Sublingual Oils vs Vapor – Which Are Best?

Looking at the comparison chart you can see the differences between these two popular delivery methods. CBD sublingual oils are taken by placing the desired amount of drops under the tongue and holding for 40-60 secs before swallowing. CBD Vapor is taken by puffing on a vaporizer pen (vape) with the desired CBD vaporizer cartridge.

Many people do not like vaping so the choice to use a sublingual oil is easy. Others may choose a vapor product over a sublingual oil because of the higher absorption rate, faster onset and convenience of carrying it on your person. Some prefer the sublingual oils because the effects last longer, it is easier to dial-in an exact dosage, and easier to take higher dosage servings. Many customers will opt to do both, using the sublingual oil for the main dose and a vape pen to supplement between doses. This is especially helpful for people tackling anxiety or chronic pain who may need to supplement throughout the day.

6. Possible Side Effects Of CBD And Drug Interaction

There are multiple studies demonstrating the effectiveness of CBD in treating various conditions. Most of these studies conclude that CBD (cannabidiol) is safe and virtually free of side effects.

A review on the Safety and side effects of cannabidiol by the NCBI for example suggests that controlled CBD (cannabidiol) administration is safe and non-toxic in humans and animals. It also does not induce changes in food intake; nor does it affect physiological parameters like heart rate, body temperature or blood pressure. Also, according to this review paper, “high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.”

There are very few known side effects of CBD, these are mostly minor but you should be informed before taking CBD:

  1. Inhibition of hepatic drug metabolism – CBD and other plant cannabinoids can potentially interact with some pharmaceuticals by inhibiting the activity of cytochrome P450, a family of liver enzymes. This key enzyme group is responsible for metabolizing some of the drugs we consume. At sufficient dosages, CBD will temporarily deactivate cytochrome P450 enzymes, thereby altering how we metabolize certain compounds. A 2013 report on a clinical trial using GW Pharmaceutical’s Sativex, found no interactions with CYP enzymes when approximately 40mg of CBD were administered.
    GRAPEFRUIT WARNING: If your medication has a grapefruit consumption warning label then you should not take CBD without first talking to your doctor or pharmacist to see if CBD will inhibit the efficacy of your medication.
  2. Dry mouth – Some people have reported an unpleasant dry sensation in the mouth.
  3. Increased tremor with Parkinson’s at high CBD dosages – There are studies showing the potential of CBD to help alleviate symptoms of Parkinson’s disease. However, there have been reports of CBD increasing tremors when taken at very high dosages. Reducing intake to a smaller dosage will typically eliminate increased tremors.
  4. Lightheadedness – In cases where extremely high dosages of CBD are being taken some people have reported temporary lightheadedness.
  5. Drowsiness – Higher dosages of CBD may cause of drowsiness. If you are affected this way, you should not operate machinery or drive a vehicle. Conversely, due to its bi-phasic nature, micro-doses of CBD act as a wake-inducing agent.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking CBD if you are pregnant or breast feeding. Stay on the safe side and avoid use.

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    CBD for Type 2 Diabetes: What Are the Benefits and Risks?

    You probably don’t have to look farther than your local drugstore or beauty product supplier to know CBD has taken a starring role in everything from sparkling water and gummies to tincture oils and lotions. Some may even say that CBD is the “it” ingredient of this day and age.

    You’ve probably also heard that CBD — which is an abbreviation for cannabidiol — can help with stress, anxiety, and pain. “When people are in pain, they have a stress response, which causes an increase in cortisol and an increase in blood sugar,” says Veronica J. Brady, PhD, CDE, a registered nurse and an assistant professor at the Cizik School of Nursing at the University of Texas in Houston. Relieving pain can help alleviate the stress response and improve blood sugar levels, as well as improve sleep, she adds.

    If you’re managing type 2 diabetes, it’s natural to be curious about whether CBD might help you manage those symptoms, too, to help stabilize your blood sugar. Some healthcare professionals say CBD may play a role in treating diabetes, but it’s important to understand that the only health condition CBD has proved effective for is epilepsy in kids. The jury is unfortunately still out, because of a lack of comprehensive research on CBD and type 2 diabetes.

    “We don’t know that THC or CBD exerts an effect on diabetes itself, and that means control of blood sugars,” says Cory Toth, MD, a neurologist at Fraser Health at Burnaby Hospital in British Columbia. He adds that pain relief is the number one reason people with diabetes use CBD and tetrahydrocannabinol (THC), another compound found in cannabis, in Canada. It’s worth noting that CBD does not cause psychoactive effects like THC, its chemical cousin.

    RELATED: What Is CBD Oil? Uses, Benefits, Side Effects, and More

    Why People With Type 2 Diabetes Are Considering CBD

    One thing is for sure about CBD: People with type 2 diabetes are taking an interest in the ingredient as a management tool.

    In Nevada, where Dr. Brady used to work as a certified diabetes educator, her patients with type 2 diabetes used CBD for nerve pain. She says patients would use CBD in a tincture or in oils that they rubbed on painful areas, including their feet. Patients could buy CBD at medical marijuana dispensaries, which would offer dosing instructions. “They worried about the impact on their blood sugars,” says Brady.

    Ultimately, though, Brady says that her patients reported that CBD reduced their nerve pain and improved their blood sugar. She adds that those people who used CBD oils for nerve pain also reported sleeping better.

    Heather Jackson, the founder and board president of Realm of Caring in Colorado Springs, Colorado, a nonprofit that focuses on cannabis research and education, also senses an interest in CBD within the diabetes community. “In general, especially if they’re not well controlled, people are looking at cannabinoid therapy as an alternative, and usually as an adjunct option,” says Jackson, adding that callers have questions about CBD for both blood glucose control and neuropathy pain.

    Realm of Caring receives an average of 7,000 inquiries about cannabis a month, Jackson says. The organization keeps a registry of these callers, where they live, and their health conditions. Jackson says that people with type 2 diabetes are not a large percentage of the callers, but they currently have 330 people with diabetes in their database.

    Jackson says that Realm of Caring does not offer medical advice, and it does not grow or sell cannabis. Instead, it offers education for clients and doctors about cannabis, based on its ever-growing registry of CBD users, their conditions, side effects, and administration regimen. “We are basically educating,” says Jackson. “We want you to talk to your doctor about the information you receive.”

    RELATED: How Type 2 Diabetes and Anxiety Are Connected

    Scientific Studies on CBD and Type 2 Diabetes, and Barriers to Research

    Despite interest among people with type 2 diabetes, large, rigorous studies showing how CBD may affect type 2 diabetes are lacking, says Y. Tony Yang, MPH, a doctor of science in health policy and management and a professor at George Washington University in Washington, DC. Specifically absent are randomized controlled trials, which are the gold standard of medical research, per a June 2016 article in the New England Journal of Medicine.

    But early research may suggest the two are worth studying further. For example, a small study published in October 2016 in Diabetes Care in the United Kingdom of 62 people with type 2 diabetes found that CBD did not lower blood glucose. Participants were not on insulin, nor were they on any diabetes drugs, and they were randomly assigned to five different treatment groups for 15 weeks: 100 milligrams (mg) of CBD twice daily; 5 mg of THCV (another chemical in cannabis) twice daily; 5 mg CBD and 5 mg THCV together twice daily; 100 mg CBD and 5 mg of THCV together twice daily; or placebo. According to the authors, THCV (but not CBD) significantly improved blood glucose control.

    A Canadian study published in Pain of 37 people with diabetes found that a synthetic cannabinoid called nabilone improved nerve pain. “We also found patients had better sleep measures, so their sleep was more complete. Anxiety levels improved to a smaller amount,” says Dr. Toth, who led the study.

    “Pain has a lot of neighbors,” Toth says. “If you have chronic pain, you typically have sleep issues, raised levels of anxiety, and depression. So, we thought nabilone could target some of those important features in those patients .” He adds that nabilone is commonly prescribed for pain in Canada.

    Other CBD research is still evolving. Some CBD and diabetes studies have been done in rats, which leads to findings that don’t always apply to human health. Other studies have looked more generally at the body’s endocannabinoid system, which sends signals about pain, stress, sleep, and other important functions. Still other studies, including one published in the American Journal of Medicine, have looked at marijuana and diabetes, but not CBD specifically.

    RELATED: Can Medical Marijuana Help Treat Type 2 Diabetes?

    So why aren’t there more studies of CBD in people with type 2 diabetes? “One reason is definitely regulatory barriers,” says Dr. Yang. He points to the 1970 U.S. Controlled Substances Act, which classifies cannabis as a Schedule 1 drug with the highest restrictions.

    Cannabis itself is difficult to acquire for research studies, says Yang. “It is only available through the National Institute on Drug Abuse,” he adds, which has limited supplies.

    “Another issue is funding,” says Yang. “In order to do more research, the National Institutes of Health needs to be more open-minded. And other funders must be willing to spend money.” Currently, 33 states and the District of Columbia allow cannabis for medical use and 11 states allow cannabis for recreational use.

    Historically, cannabinoids (a group of chemicals in the cannabis plant) have been lumped together, including CBD, THC, and more than 100 others. In the past decade, growers and manufacturers have been able to isolate CBD, mainly by cultivating industrial hemp that is high in CBD and very low in THC, says Jackson. The 2018 Farm Bill removed industrial hemp from the controlled substances list, clearing the way for more production and research of hemp and thus CBD.

    “There have not been a huge amount of clinical studies , but most of that relates to how the cannabinoids have been treated as a group,” says Toth. “They’ve been looked down upon. There is stigma around them,” he says.

    “It’s difficult for researchers to get access to the quantity, quality, and type of cannabis product necessary to address specific research questions on cannabis use,” says Yang.

    RELATED: How to Treat Type 2 Diabetes From the Inside Out

    Patient Use, the FDA, and the Quality and Quantity of CBD

    People with type 2 diabetes aren’t waiting for further study. Brady says her patients were open about using CBD, particularly the younger patients. She says one of her older patients was initially uncomfortable about buying CBD in the same shop that sold marijuana but eventually gave in. Brady adds many people associate CBD with smoking marijuana, but she cautions that CBD and THC are very different chemicals in terms of the way they affect the body.

    The U.S. Food and Drug Administration (FDA) approved the first CBD medication in 2018, for treating childhood epilepsy. Currently, there is no other FDA-approved CBD medication for diabetes or any other condition, according to the FDA. In December 2018, the FDA said it was unlawful under the Federal Food, Drug, and Cosmetic Act to sell food or dietary supplements containing CBD. In April 2019, the FDA stated that it’s taking new steps to evaluate cannabis products, and it held a public hearing about cannabis products in May 2019.

    “The FDA, for the time being, has focused its limited enforcement resources on removing CBD products that make claims of curing or treating disease, leaving many CBD products for sale,” wrote Pieter Cohen, MD, and Joshua Sharfstein, MD, in a July 2019 perspective in the New England Journal of Medicine. Dr. Cohen is an assistant professor of medicine at Harvard Medical School in Boston, and Dr. Sharfstein oversees the office of public health practice and training at the Johns Hopkins Bloomberg School of Public Health in Baltimore.

    Of the CBD products on the market, Jackson says it’s often difficult to know what’s inside. A study published November 2017 in the Journal of the American Medical Association found that only 30 percent of CBD products were accurately labeled, with under- and over-labeling of CBD, and some products containing unlisted chemicals such as THC.

    At the time this article was written, a spokesperson for the Joslin Diabetes Center in Boston, an affiliate of Harvard Medical School, said that the research center was unable to provide feedback about CBD and type 2 diabetes.

    Jackson points out that CBD could affect certain cholesterol and blood pressure drugs, and a study published June 2017 in Cannabis and Cannabinoid Research detailed these interactions. Other side effects of CBD include tiredness, diarrhea, and changes in weight or appetite, the researchers write.

    “What you put in your body is really important,” says Jackson, adding that’s especially true for people with major health conditions including diabetes. Jackson speaks from personal experience as a mom finding CBD treatments for her son’s epilepsy. She says consumers should ask manufacturers whether CBD products are free of mold, pesticides, and other toxins.

    Realm of Caring, Jackson’s nonprofit, created a reference sheet for evaluating products and manufacturers. It also endorses products that adhere to standards such as those from the American Herbal Products Association and the FDA’s Current Good Manufacturing Practice regulations.

    RELATED: 6 Surprising Alternative Treatments That Worked for People With Diabetes

    How to Talk to Your Healthcare Provider About Using CBD for Type 2 Diabetes

    Jackson and Brady advise that people considering CBD for diabetes ask their providers about the complementary therapy before adding it to their treatment plan. Brady says it’s difficult to find research about CBD and type 2 diabetes, even in her capacity as a diabetes educator. Still, from her experience, if people are looking for a natural way to manage pain, it’s worth a conversation with their healthcare provider. “It’s something that should be talked about, especially if they’re having significant amounts of pain, or really any pain at all associated with their diabetes,” says Brady.

    “It’s a reasonable alternative,” says Brady. “As it gains in popularity, there needs to be some information out there about it.

    Can marijuana help people with diabetes?

    Share on PinterestMarijuana has a range of potential benefits for people with diabetes.

    An advocacy group called the American Alliance for Medical Cannabis (AAMC) suggest that marijuana might have the following beneficial effects in people with diabetes:

    • stabilizing blood sugar levels
    • lowering arterial inflammation due to its antioxidant properties
    • reducing neuropathic pain, a complication of diabetes
    • keeping blood vessels open, which may reduce blood pressure over time and improve circulation
    • providing relief from muscle cramps
    • relieving gastrointestinal pain and cramping

    However, the AAMC also caution that the results of studies on these benefits are contradictory. Research into medicinal marijuana is still ongoing, and further studies are necessary to help both medical professionals and patients understand the therapeutic and adverse effects more clearly.

    Marijuana may offer other benefits for people with diabetes.

    Smaller waist size and lower risk of obesity

    Being overweight or having obesity is one of the most significant risk factors for the development of type 2 diabetes.

    Studies show that marijuana may help reduce the risk of obesity, which may decrease a person’s likelihood of diabetes in turn. For example, a 2013 study of 4,657 people, including 579 current marijuana users and 1,975 past users, identified an association between smaller waist size and marijuana use.

    On average, people who were still using marijuana at the time of the study had a waist circumference that was 1.5 inches (3.8 centimeters) less than that of people who were not.

    This finding supports earlier research, which found that the occurrence of obesity was lower among people who used cannabis than among those who did not.

    Increased insulin sensitivity

    The body’s ability to use insulin effectively is vital for health. However, in people with type 2 diabetes, the body is less sensitive to the effects of insulin and, therefore, less responsive to this hormone.

    Research has shown that marijuana users may have increased insulin sensitivity.

    In a large study, scientists observed that the fasting insulin levels of users were 16 percent lower than those of both former users and nonusers. The levels of insulin resistance among this group were also 17 percent lower on average.

    The results of a 2016 study, which recruited people with type 2 diabetes who were not taking insulin, indicated that a form of the cannabinoid THC had the following effects:

    • a significant drop in fasting blood glucose
    • improved production of insulin
    • raised levels of adiponectin, a protein that regulates blood sugar

    Topical CBD hemp oil

    A 2014 study found that a topical marijuana treatment that combined CBD and THC led to reduced symptoms in participants with peripheral neuropathic pain.

    Using a spray, people can apply these cannabinoids directly to their hands and feet to reduce the pain and tingling sensations that are symptomatic of diabetic neuropathy.

    A variety of CBD and hemp oils, lotions, and balms are available to purchase online.

    People should always purchase these products from a reputable supplier and check with a doctor first to ensure that they are safe to use. If sellers store marijuana in damp areas, it can produce dangerous molds that can cause serious lung disease.

    Anti-inflammatory properties

    Inflammation plays a role in the development of types 1 and 2 diabetes and other chronic diseases.

    Some 2015 research suggests that the anti-inflammatory properties of CBD can treat the inflammation that contributes to diabetes and some of its associated complications.

    Protection against retinopathy

    Diabetic retinopathy is the leading cause of vision loss in people living with diabetes.

    According to the National Eye Institute, it is also the most common cause of blindness in adults of working age.

    The results of research on animals suggest that 1 to 4 weeks of CBD treatment can provide significant protection from diabetic retinopathy.

    Managing neuropathy pain

    Diabetic neuropathy is a common complication of diabetes.

    It is a form of nerve damage that occurs most often in the legs and feet but might also develop in other parts of the body. Neuropathy is often extremely painful, and it can be fatal in some cases.

    The authors of a 2015 study involving people with neuropathic foot pain concluded that inhaling cannabis can provide several hours of relief from diabetic neuropathic pain.

    The researchers noted that higher doses of THC provided greater pain relief.

    Cannabidiol (CBD) oil is derived from the CBD compound which is found in cannabis, and has been associated with having a number of potential therapeutic uses, including for diabetes.

    Cannabis oil is legal to buy and consume in the UK, with CBD oil first stocked in UK shops in 2018.

    Unlike the psychoactive tetrahydrocannabinol (THC) substance which gives marijuana users the “high” feeling, CBD oil contains less than 0.2% THC. Because CBD is not psychoactive, it does not change a user’s state of mind, but it does appear to produce significant changes in the body.

    Cannabis pills containing only CBD and not THC were sold legally for the first time in Europe in 2015.

    What is CBD oil?

    CBD oil is made by extracting CBD from the cannabis plant. It is then diluted with a carrier oil such as coconut or hemp seed. The concentration and uses of CBD oils can vary.

    Growing research is demonstrating how CBD oil can provide pain relief for people with certain health complications, without the addition of any mind-altering effects.

    CBD oil and diabetes

    The benefits of CBD for treating diabetes-related health problems may include reduced inflammation and improved blood glucose control.

    Meanwhile, in 2016, University of Nottingham researchers showed that CBD in combination with another cannabis compound called tetrahydrocannabivarin (THCV), helped lower blood sugar levels and increase insulin production in people with type 2 diabetes.

    GW Pharmaceuticals, a UK-based company, has developed a cannabis spray called Sativex which utilises both CBD and THCV to help treat muscle spasms in multiple sclerosis. The company is in the process of developing a similar spray which could aid blood sugar control in type 2 diabetes.

    Studies have also shown that CBD oil has benefits for people with epilepsy, mental health disorders such as anxiety and depression, and helping people quit smoking.

    How does CBD oil work?

    CBD oil is believed to activate a number of receptors in the body, influencing the body to produce naturally-occurring cannabinoids.

    The human body has two receptors for cannabinoids: CB1 and CB2. Most CB1 receptors are found in the brain, which deal with coordination, movement and appetite. CB2 receptors are more commonly found in the immune system and affect pain and inflammation.

    By activating receptors such as adenosine, serotonin and vanilloid, CBD can affect your body temperature, inflammation and perception of pain.

    How to use CBD oil

    CBD oil can be used in a number of ways. Most often, instructions will recommend putting a few drops under the tongue 2-3 times a day. Alternatively, some CBD oils can be mixed into different foods or drinks, taken from a pipette or used as a thick paste to be massaged into the skin.

    Side effects of CBD oil

    A 2015 study of CBD oil effects in humans concluded that CBD is generally well-tolerated and considered safe. However, it can cause certain adverse reactions such as diarrhea and stomach ache.

    Additionally, CBD may interact with existing medication. It is therefore important to discuss using CBD oil with your doctor beforehand, to help ensure it is used safely and any harmful effects are avoided.

    Cannabidiol (CBD) oil has been one of the most popular items to hit the wellness scene in the last year. Emerging research has suggested potential therapeutic benefits of the CBD compound and, while promising, it is still an area that needs more research and clarification.


    Here are the top four things to know about CBD oil:

    1. Is CBD oil marijuana?

    CBD oil is not marijuana. Cannabis is a plant that contains over eighty chemical compounds — the two most well-known are delta-9-tetrahydrocannabinol (THC) and CBD. CBD is the non-psychoactive compound, meaning it does not produce the feeling of a “high,” or intoxication, derived from the cannabis sativa, or hemp, plant. CBD oil derived from industrial hemp plants by definition contains no more than 0.3% THC. This differs from the cannabis indica, or marijuana, plant which typically contains higher levels of THC, the psychoactive compound, along with CBD.

    2. Is CBD oil legal?

    Yes, CBD oil extracted from industrial hemp plants is legal. The passage of the 2018 Farm Bill removed hemp, defined as cannabis with less than 0.3% THC, from the Schedule 1 controlled substance list, meaning it is now an ordinary agricultural commodity. The 2018 Farm Bill did uphold the Food and Drug Administration’s (FDA) authority to regulate cannabis and cannabis-derived products, meaning it is subject to FDA regulations.

    3. What are the benefits of CBD oil for diabetes?

    Current research is examining the potential therapeutic benefits of CBD, and a few published studies have focused specifically on the areas of pediatric epilepsy, irritable bowel disorders and pain relief. There is still much research that needs to be done, and consumers should be aware that there is a lot of misinformation and anecdotal claims of reported benefits online, so finding reputable sources for information is important. The FDA has approved one cannabis-derived medication, Epidiolex, as treatment for two forms of epilepsy, as well as three cannabis-related drug products for the treatment of anorexia associated with weight loss in people with AIDS. Other CBD products that are not one of the FDA-approved medications cannot make claims about curing or treating disease.

    4. Is there a direct link between improved diabetes management and the use of CBD?

    Currently, there is not much evidence-based research to suggest a benefit of CBD oil for diabetes management. There have been a few diabetes-related studies, but most have been done in rodents and have not been replicated with human studies. One human study on individuals with type 2 diabetes was published in 2016 in the journal Diabetes Care. The study examined the potential impact of CBD as well as another cannabis compound, THCV, on HDL (“good”) cholesterol, glycemic control, and insulin sensitivity, as well as other markers. Results showed that while CBD did improve levels of resistin, which is associated with insulin resistance, and increase levels of one of the incretin hormones, it was not found to improve glycemic control or have any metabolic effects. However, the other compound examined, THCV, was found to reduce fasting plasma glucose levels, and the study authors suggested this might warrant further research. It is clear that more research is needed to examine if there might be any benefit for diabetes self-management.

    We will continue to learn more about CBD as the depth of research expands. In the meantime, make sure to use reputable sources for information and consider talking to your health-care provider before including CBD as part of your wellness routine.

    Want to learn more about CBD? Read “Six Food Trends for 2019.”

    CBD Oil for Diabetes: Benefits, Dosage, & Top Picks

    Statistics regarding diabetes in the United States are alarming, with more than 100 million diabetes or prediabetes in 2017, as reported by the Centre for Disease Control and Prevention.

    Diabetes is a serious disease. If neglected, it can wreak havoc on your health in many different areas, sometimes leading to such severe consequences as organ failure or death.

    There are many ways to control the symptoms of diabetes or prevent its development, but what’s the link between CBD oil and diabetes?

    Can CBD oil really help?

    Current research, as well as individual testimonials, suggest that CBD may both relieve and prevent diabetes by engaging the endocannabinoid system through cannabinoid receptors in the body and brain.

    In this article, I will cover:

    • The best CBD brands on the market as of right now
    • Basic information about diabetes and its collateral side effects
    • The effects of CBD on diabetes (type 1 and type 2)
    • How to use CBD oil for diabetes

    How is that? Let’s go ahead and learn everything there is to know about CBD oil for diabetes.

    Best CBD Oil Brands for Diabetes

    While CBD oils are generally effective in the management of various symptoms, you shouldn’t just buy any CBD oil. There are tons of choices out there and you have to be sure that the one you choose is made of high-quality ingredients.

    With that, allow me to share with you my ranking of the best CBD oil brands on the market as of right now.

    1. Royal CBD


    • Royal CBD uses American-grown, organic hemp
    • The company uses full-spectrum CBD to make their oils
    • The oil is available in three strengths: 250mg, 500mg, and 1000mg
    • Royal CBD extracts are suspended in premium MCT oil for faster absorption
    • Each batch of product has been tested in a 3rd-party laboratory for potency and safety


    • Slightly more expensive than the other brands

    My Thoughts on Royal CBD:

    Royal CBD is a company specializing in manufacturing premium CBD oils — made from organically grown US hemp. Unlike many brands that try to make their name in the industry, this company is pretty simple. They offer CBD in basic formats, such as oils, capsules, and gummies.

    Their CBD oil is available in three different potency options to address different dosage needs. This is a full-spectrum extract — it contains pure CBD along with other cannabinoids such as CBG, CBN, CBDA, CBC, and trace amounts of THC (less than 0.3%).

    Each batch of their product is tested in 3rd-party laboratories to make sure there aren’t any inconsistencies in the CBD potency and purity levels. The results are available on Royal CBD’s website.

    2. CBDPure


    • CBDPure products are sourced from organic hemp
    • Extracted with CO2
    • Lab-tested for potency and purity
    • 100% Satisfaction Guaranteed program (full refund within 90 days)


    • Narrow product range
    • The oil has a slightly lower strength than the competition

    My Thoughts on CBDPure

    CBDPure was founded in 2016 by Colorado natives, with a simple mission — to make high-quality CBD oils made from locally grown hemp. The company offers three different strengths of their CBD oil as well as easy-to-take softgel capsules.

    While this is a very modest product range, CBDPure has perfected both of these products. These full-spectrum extracts are made with supercritical CO2 and tested in third-party laboratories for potency and purity.

    When it comes to their CBD oil, it’s not as potent as the other brands in this ranking, but it does a decent job at alleviating mild symptoms or if you use CBD for the extra boost of your health. If you want something potent, you can go for their softgels — each capsule has 25mg of full-spectrum CBD.

    If you’re not satisfied with your product, CBDPure has a 100% Satisfaction Guaranteed program. They will give you a full refund if you send your order back within 90 days.

    3. Hemp Bombs


    • This company uses certified organic hemp from European farms
    • Their CBD isolate is extracted with CO2
    • Extremely potent — up to 4000mg of CBD per bottle
    • Extensive product range
    • THC-free
    • Odorless and flavorless
    • All products are tested in 3rd-party laboratories for potency and purity


    • This is a CBD isolate — you don’t get the synergy from other cannabinoids
    • Most people don’t need such high doses of CBD

    My Thoughts on Hemp Bombs:

    Hemp Bombs is a great choice for people looking for high-quality CBD isolate and those who’d like to try different CBD formats. The company specializes in making isolate-based CBD products.

    Their product lineup features traditional CBD options such as oil, capsules, vapes, and edibles, as well as less common products like CBD-infused beard lotion, tattoo ointment, or syrup.

    Hemp Bombs gives you more affordable CBD extracts at the cost of some efficacy. Since this is 99% pure isolate, their products don’t offer the synergy from other cannabinoids. Thus, the effective dosage may be higher than with full-spectrum CBD.

    Nevertheless, if you’re allergic to other ingredients than CBD in hemp products, or you must take periodical drug tests at work and can’t get a false positive for THC, this is the best company to buy isolate from.

    4. CBDistillery


    • CBDistillery uses Colorado-grown hemp to make their extracts
    • The company’s products are available as full-spectrum CBD or isolate
    • Wide product range
    • Each batch of product has been tested in a 3rd-party lab for quality
    • Their CBD oil is very affordable


    • Their hemp isn’t organic
    • No flavored options available

    My Thoughts on CBDistillery:

    CBDistillery sells a wide range of CBD products, including CBD oil, capsules, and gummies — available as full-spectrum CBD or isolate (ZERO THC).

    The company also has a very impressive potency range for their CBD oil, offering from 250–5000mg of CBD per bottle. Their products are good for people looking to buy inexpensive CBD oil without compromising its quality — the 250mg bottle costs only $20.

    Although CBDistillery doesn’t use organic hemp in their extracts, the plants come from domestic growers and are processed with supercritical CO2 for maximum purity. On top of that, CBDistillery tests all its products in a certified laboratory for potency and potency and safety.

    5. NuLeaf Naturals


    • The company uses organic hemp to make CBD oil
    • These are full-spectrum extracts — you get the synergy from other cannabinoids
    • NuLeaf products are tested for potency and safety in a 3rd-party lab
    • Available in 5 different sizes — you can get yourself supplied for months to come
    • Up to 4850mg of CBD per bottle


    • NuLeaf sells only CBD oil for humans and pets
    • No flavored options available
    • Slightly more expensive than the market’s average

    My Thoughts on NuLeaf Naturals:

    NuLeaf Naturals has been selling whole-plant hemp extracts for over 5 years now. The company was established by entrepreneurs passionate about the benefits of plant-based supplements.

    The company specializes in making clean, potent extracts for both humans and pets. NuLeaf sources its hemp from Colorado farmers who use organic practices for growing their plants.

    NuLeaf Naturals may not offer the widest product range out there, but they make up for it with the multitude of different sizes to choose from. Their high-grade full-spectrum CBD oil is available from 240mg to 4500mg per bottle.

    Choosing the largest option will get you supplied for months. However, the potency remains the same regardless of the size — offering 2.4 mg of CBD per drop.

    What is Diabetes?

    Diabetes is a disease that occurs when your blood sugar levels are too high. Blood sugar (glucose) is your primary source of energy and is sourced from the food you eat.

    Insulin, a hormone released by the pancreas, helps transport glucose from food into your cells to be used for energy.

    With chronically high blood sugar levels, your body can’t produce enough insulin to manage them efficiently, which leads to storing more glucose in the bloodstream. This, in turn, can trigger an array of health problems, such as high blood pressure, heart disease, clogged arteries, mood swings, depression, and more.

    Milder cases of diabetes are called “a touch of sugar” or “borderline diabetes,” but that doesn’t mean they should be neglected. In fact, every case of diabetes is serious.

    Different Types of Diabetes

    The two most common types of diabetes are type 1 and type 2 diabetes. There’s also gestational diabetes that can affect pregnant women.

    Type 1 Diabetes

    Type 1 diabetes is an autoimmune disorder that happens when your body doesn’t make insulin. This caused by the immune system attacking and destroying the cells in your pancreas that are responsible for insulin production. Type 1 diabetes is usually diagnosed very early — mostly in children — although it can also appear at any age. People with type 1 diabetes have to rely on insulin injections to stay alive.

    Type 2 Diabetes

    If you’ve been diagnosed with type 2 diabetes, your body doesn’t produce enough insulin or have problems using it to manage blood glucose levels. You can develop type 2 diabetes at any age, even if you’re a child. However, this type of diabetes affects middle-aged and elderly people — it’s also the most common form of this disease.

    Gestational Diabetes

    Gestational diabetes may develop in some women when they’re pregnant. Usually, this type of diabetes disappears once the baby is born. However, if you’ve had gestational diabetes during pregnancy, you’re more likely to develop type 2 diabetes later in life.

    Consequences of Neglected Diabetes

    As mentioned, diabetes happens when you have notoriously high blood glucose levels. This can lead to a number of serious problems, including:

    • Dental disease
    • Eye problems
    • Foot problems (restless leg syndrome)
    • Heart disease
    • Stroke

    If you have type 2 diabetes, you can take certain steps to stop its development. Maintaining an active lifestyle, cutting down on sugars (and carbohydrates in general) while increasing the intake of healthy fatty acids, as well as reducing the amount of stress in your life can make a significant improvement in your health. The same conditions apply for preventing diabetes

    Supplementation is part of everyday nutrition nowadays. We use supplements to level up nutritional deficiencies and bolster our immunity. As it turns out, supplementation with CBD oil may help you relieve symptoms of diabetes and also address the roots of the problem.

    What Are the Effects of CBD on Diabetes?

    CBD and diabetes can go hand in hand. Depending on the type of diabetes you have, CBD can potentially help mitigate or lessen some of the symptoms that make this disease particularly problematic to live with. Studies suggest that cannabinoids can also be used as diabetes preventing agents.

    Here are just a few possible benefits of taking CBD oil for diabetes, both type 1 and type 2

    1. Better Regulation of Blood Sugar Levels

    Diabetes is a prevalent disease among obese people. The reason for this is due to how diabetes gets triggered in the first place.

    When your body receives sugar, the pancreas releases insulin, a hormone that regulates blood glucose levels and enables the absorption of glucose into the cells to use it for energy.

    Excess body fat causes the blood cells to be less sensitive to insulin. This compromises the body’s ability to absorb sugar and is officially referred to as insulin resistance.

    When your body starts to store sugar instead of using it for energy, it’s a beeline to gaining extra pounds.

    Therefore, if you want to prevent diabetes or reduce its symptoms, it’s important that you maintain a healthy weight.

    According to recent studies, people who frequently use cannabis have a smaller waist circumference compared to non-users. They also have lower insulin resistance, which contributes to a speedier metabolism.

    The reason for this may be the CBD’s ability to trigger the “fat browning” process. Fat browning turns the white fat cells — the ones you store as the excess body fat — to brown cells which can be easily broken down and used for energy during activity and exercise.

    While CBD isn’t an overnight fix to your problems with weight, adding this compound to exercising and a healthy diet may support these activities to make the whole process more effective.

    2. Lower Insulin Resistance

    When the cells in the human body turn down insulin, they are unable to facilitate glucose transportation to cell tissues.

    This can result in a glucose buildup in the body, which leads to increased blood sugar levels. Ideally, the cells should be able to accept the insulin in order to use them for energy — in type 2 diabetes, the body refuses to do this.

    Some research indicates that CBD could be the key to improving the body’s efficiency in absorbing and using insulin.

    A 2013 study published in the American Journal of Medicine featuring a sample of 4,657 adults (both men and women) found that cannabis users have a 16% faster insulin level and 17% lower insulin resistance level compared to non-users.

    4. Reduced Inflammation of Pancreas

    CBD produces anti-inflammatory effects that may help to mitigate some of the symptoms of diabetes — especially when it comes to delaying the onset of type 1 diabetes.

    Experts argue that this disease develops after chronic inflammation of the cells in the pancreas responsible for insulin production.

    Inflamed pancreas cells become damaged to the point they almost can’t produce insulin — it’s a signal that you’re developing type 1 diabetes.

    Supplementing yourself with CBD may help you delay this process, especially among those who are more likely to suffer from the condition due to lifestyle factors or genetic predisposition.

    5. Better Blood Circulation

    Both sufferers of type 1 and type 2 diabetes should be particularly watchful when it comes to their blood pressure levels. The disease, along with obesity, often leads to hypertension.

    This entails the risk of kidney disease, and in more severe cases, can result in blindness.

    So how can you maintain healthy blood pressure with CBD oil?

    Research shows that CBD dilates the blood vessels, making it easier for blood to flow. This ensures better control of the blood pressure. Scientists also suggest that over time, cannabinoids can help reduce blood pressure in healthy people, reducing the chances of developing hypertension.

    CBD Oil Dosage for Diabetes

    Frankly speaking, there aren’t definitive dosage guidelines when it comes to dosing CBD. The FDA doesn’t even have an official serving size for cannabidiol.

    That’s because too many factors come into play when it comes to estimating the effective dose — it depends on your body weight, metabolism, lifestyle choices, the potency of your product, and whether or not you have used CBD oil before.

    To begin with, I recommend choosing low dosages and then assessing the effects and adjusting the dosage as necessary.

    Don’t worry, there are no known cases of CBD overdose. When you take too much CBD at a time, you may experience mild side effects such as dry mouth, dry eyes, or a drop in blood pressure to the point where you might feel sleepy and dizzy.

    The majority of CBD oil users never take more than 25mg of CBD daily. Those with mild conditions take 40mg to 50mg of CBD a day. Severe cases call for taking 100mg to 150mg of CBD daily (up to 400 mg in epilepsy patients)

    Final Thoughts on Finding the Best CBD Oil for Diabetes

    Diabetes is a serious disease and so are its complications. If you fail to take control of your blood sugar, you can end up with severe health consequences.

    Numerous studies suggest that CBD has the potential to relieve and even lessen the symptoms of diabetes. Not only that, but CBD can also delay the onset of type 1, and prevent the development of type 2 diabetes.

    If you’re considering taking CBD oil to manage diabetes, speak to your doctor about your plans and be sure to discuss the CBD oil dosage for your symptoms. Remember that CBD may need some time to take effect, so stay patient and monitor the effects.

    CBD for Diabetes

    CBD: Therapeutic Benefits For Diabetes Patients


    If you are one of the millions of people living with diabetes, you know how challenging it can be to manage the disease.

    And most prescribed medications come with a long list of potential side effects ranging from upset stomach to liver disease.

    But the good news is…

    Cannabidiol (CBD) has been well-researched as a potential treatment for diabetes. And it’s showing great promise. With mild and infrequent side effects, CBD may be the answer many diabetic patients have been waiting for.

    Want to try CBD to treat your diabetes?

    We’ll give you info on how to get started in just a minute.

    First, let’s take a look at what makes CBD such a powerful therapeutic option for treating wide a variety of conditions – including diabetes.

    It all starts with the internal system responsible for maintaining homeostasis; it is known as our endocannabinoid system.

    CBD interacts with endocannabinoid receptors found throughout our brain and body. These interactions can have powerful therapeutic benefits – and that fairly recent discovery has led to exciting new areas of research.

    Which means…

    CBD may soon play a much larger role in managing the symptoms of diabetes, and may someday have the potential to prevent or reverse the disease.

    How is this possible?

    CBD Interacts with Receptors in the Pancreas

    Endocannabinoid receptors are highly prevalent in the pancreas. In fact, these receptors have been found specifically in the islet cells of the pancreas – exactly where insulin is produced in the body.

    What does this mean?

    Well, for the moment it means more research is needed. But the indication is that these receptors may play an important role in the production of insulin, which of course will be key in determining new diabetes treatments.

    Can CBD Prevent Diabetes?

    In a 2006 study, CBD demonstrated the remarkable capability to delay the onset and decrease the incidence of Type 1 diabetes in laboratory mice.
    While clinical studies are still needed, early results are revealing that CBD may have the potential to prevent diabetes – which would be life-changing for future generations.

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    Can CBD Cure Diabetes?

    The short answer is, probably not. BUT — we shouldn’t rule out the possibility before more research is done.

    Studies have shown that CBD helps protect islet cells so they can produce insulin and healthy glucose metabolism can take place.

    Perhaps the most exciting cure-focused research is…

    Scientists have successfully used CBD to reverse early stage Type 1 diabetes in mice. While this is a long ways away from being a prescription-ready treatment, this is exciting and hopeful news for millions.

    Preparations for clinical trials are underway.

    What we do know for sure is…

    CBD is providing new hope for preventing, treating, and possibly curing diabetes. While we await further research with anticipation, we can take advantage of the many ways CBD can ease the symptoms associated with diabetes.

    Here’s how CBD can help treat the symptoms of diabetes:

    Stabilizes Blood Sugar Levels
    Research has shown that CBD improves overall metabolism and its anti-inflammatory properties directly treat glucose metabolic disorders.Reduces Chronic Inflammation
    Cannabis is known for its anti-inflammatory properties, so this one is probably not a surprise. Chronic inflammation plays a key role in 2 diabetes and its associated resistance to insulin. Researchers believe CBD could be an effective treatment for reducing this inflammation and enabling healthy glucose metabolism.Promotes Metabolism
    Obesity plays a major role in Type 2 diabetes and associated complications. CBD can help to suppress appetite and increases fat breakdown to promote metabolism. This gives the endocannabinoid system a chance to re-balance.

    CBD has neuroprotective properties that can reduce nerve pain often associated with diabetes. Many people with diabetes experience limited feeling in their hands and feet. Typically this is due to insufficient blood flow, which can break down tissues, cause them to die, and increase the risk for infection. CBD is fully recognized and federally patented as a neuroprotectant with the capability to reduce the breakdown of tissue by up to 30%.Protection Against Diabetic Retinopathy
    Retinopathy is caused by damage to the blood vessels in the eyes. When the damage is caused by high levels of blood glucose, it is known as diabetic retinopathy. Diabetic retinopathy is the number one cause of blindness in adults. For people with Type 1 diabetes who have managed the disease for at least 20 years, nearly all are at risk of developing diabetic retinopathy. For people who have managed Type 2 diabetes for at least 20 years, 80% are expected to develop the condition. Lab research has revealed that CBD provides significant protection against it.Diabetic Cardiomyopathy
    People with diabetes have an increased risk of developing cardiomyopathy – a disease that causes the heart muscle to become enlarged or thickened. It is a serious condition that can lead to heart failure. Research published in the Journal of the American College of Cardiology has identified that CBD can reduce symptoms of diabetic cardiomyopathy in laboratory studies.

    High blood pressure is commonly associated with patients who have Type 2 diabetes. In fact, an estimated 80% of people with Type 2 diabetes have elevated blood pressure. In preclinical studies, CBD has shown its capability to reduce blood pressure.Vasodilator
    CBD is a vasodilator which means it widens arteries and blood vessels, reduces pressure, and allows for more blood flow. This improves circulation which is particularly important for diabetics.Relieves Gastrointestinal Pain and Cramping
    Gastrointestinal pain (GI) and cramping is not uncommon for people with diabetes to experience. CBD can relieve GI pain and cramping.

    Eases Restless Leg Syndrome (RLS)
    This condition is a neurological sleep disorder that afflicts a high percentage of people with diabetes. The neuroprotective properties of CBD make it an effective treatment.

    Specific CBD Benefits for People with Type 1 Diabetes

    Insulin is the critical hormone produced in the pancreas that enables sugar (glucose) to enter cells and produce energy. In people with Type 1 diabetes, the pancreas produces little to no insulin and glucose is prevented from entering cells.

    Without this process functioning properly, the body cannot sufficiently regulate blood sugar levels.

    But luckily…

    Early research has shown exciting results that CBD can delay the onset of Type 1 diabetes. In studies with laboratory mice, CBD significantly decreased the occurrence of the disease.

    While clinical trials are still needed, preliminary results have been promising.

    People with Type 1 diabetes can also benefit from CBD’s anti-inflammatory properties. By reducing inflammation of pancreatic cells, CBD can help reduce the need for other medications that may have more serious side effects.

    Additionally, CBD can help reduce stress and anxiety, which are a common issue for patients with Type 1 diabetes and can trigger blood glucose fluctuations.

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    Specific CBD Benefits for People with Type 2 Diabetes

    People who suffer from Type 2 diabetes often struggle to lose weight, and an imbalance in the endocannabinoid system may be the reason why. CBD can help restore balance to this important system and help individuals lose weight.

    CBD’s anti-inflammatory properties also benefit people with Type 2 diabetes by suppressing the inflammatory reaction after ingesting sugar.

    And just recently…

    This is exciting news for people with Type 2 diabetes.

    Harvard Medical School researchers have recently taken an interest in a study originally published in 2013 that suggests regular marijuana use decreases insulin resistance and improves blood sugar levels.

    The study spanned five years and included data from 4,657 patients.

    Consistent cannabis users had —

    • 17% decrease in insulin resistance levels
    • 16% reduction in fasting insulin levels
    • Increased levels of HDL-C

    What does all this mean?
    While science is still unraveling exactly how CBD as an individual cannabis compound is able to provide so many benefits to diabetic patients, one thing is clear – there is a ‘significant link’ between the regular use of cannabis and healthy blood sugar levels.

    And here’s more good news —

    The cost of treating diabetes in the United States is estimated to be a staggering $327 billion. That’s the equivalent of 1 in 4 healthcare dollars spent on managing diabetes.

    The high cost of currently available diabetes medications are putting a real strain on individuals and families.

    CBD, on the other hand, is considerably more affordable. And while CBD should not be considered a replacement for doctor prescribed medications at this point, it is hopeful to know a more affordable treatment option may be in the future for diabetes patients.

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    Here’s the Key Takeaway

    This is an exciting time for cannabis research with new therapeutic benefits being discovered at a rapid pace.

    And while CBD has been the most widely researched cannabinoid, we’re still just scratching the surface when it comes to uncovering its full healing potential.

    For people with diabetes, there may be great potential to prevent, treat, and cure the disease using CBD and perhaps other cannabis compounds.

    Clinical studies will be the next defining moment in this critical research, and the results could forever change the face of this disease and how it’s managed.

    Using CBD to Manage Symptoms of Diabetes

    Here’s How to Get Started
    If you have diabetes, CBD may be able to help you manage associated symptoms. Of course, you should always discuss this – and any regimen you plan to start, with your doctor first.

    Here’s everything you need to know to get started with CBD —

    Determine Your Dosage
    Understanding the dosage of CBD to start with can take a bit of guesswork. Factors that are involved include your symptoms and experience with CBD, as well as your age and weight. To help you get started, we’ve developed this handy CBD dosage calculator.

    Choose Full-Spectrum or CBD Isolate
    A full-spectrum product will contain CBD along with all the other cannabinoids that are extracted with it. Due to the entourage effect, it is widely accepted that full-spectrum products may provide more overall benefits than isolates.

    Choose High-Quality CBD Products
    To experience the maximum therapeutic benefits of CBD, you must choose a high-quality product. How your product is grown, harvested, dried, and extracted all make a big difference in the overall quality.

    High-quality products are —

    Pesticide Free
    Look for cannabis growers who believe in organic practices, avoid harmful chemicals, and use natural methods of pest control.

    Careful Harvesting
    Cannabis growing experts understand the critical step of careful harvesting to ensure the delicate trichomes are preserved in order to produce the highest quality product.

    Extracted with CO2
    Extraction methods matter! If you’re looking for a high-quality CBD oil, consider one that has been CO2 extracted. This extraction method produces a clean, pure CBD oil. Low-quality brands typically use harsh extraction methods that involve synthetic chemicals and toxic additives.

    This is the process of applying heat to hemp flowers to activate a key compound – CBDA. The activation of CBDA provides greater therapeutic benefits. CBD oil that is not decarboxylated is less effective.

    Choose a CBD Product That’s Right for You

    There is no shortage of CBD products now available. You can completely customize your CBD experience and have a bit of fun with it.

    CBD Products Are Growing
    With CBD now legal in all 50 states, the number of CBD products on the market continues to grow. Beverages, candies, sprays, ointments, and so much more are now widely available.

    Full Spectrum CBD Oil – an Easy Way to Get Started
    Many people who try CBD for the first time, start with a CBD oil. They’re straightforward and easy to use. Still, the options can be overwhelming if you’re just getting started. That’s why we’ve created the Definitive Buyer’s Guide to Full-Spectrum CBD.

    Best CBD oil for Diabetes

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    CBD Oil for Diabetes: Exploring the Facts

    If you’ve already done some reading up on CBD, diabetes, and related symptoms, you may have heard some fairly incredulous things about the hemp-based compound and its ability to out-and-out cure the disease.

    This is far from the truth. To date, there have been no advanced clinical trials on the effects of CBD for diabetes. Moreover, the limited amount of research that has been done has been carried out on mice in a laboratory setting. This is far from the rigorous clinical conditions that doctors need in order to establish a compound as a viable medicine.

    Does CBD cure diabetes? Probably not. However, results from animal studies have shown it may be able to decrease the incidence of the disease through an immunomodulatory mechanism.

    That being said, it is no stretch to say that the therapeutic properties of CBD may be able to help with secondary symptoms of diabetes, and – as we mentioned above – may even be able to help decrease the overall prevalence of the condition.

    In this article, we talk about CBD, diabetes, low-sugar symptoms, and how active cannabis extract may play a crucial role in the near future by offering a safe, inexpensive, side-effect free form of treatment.

    CBD, Diabetes, and What You Need to Know

    Diabetes is a disease wherein the body has trouble regulating the level of sugar (glucose) in the bloodstream. In healthy individuals, the pancreas produces a hormone called insulin, which works to transport glucose molecules across cell membranes and into cells for energy production.

    In diabetics, depending on whether they suffer from Type 1 or Type 2 form of the disease, the body is either unable to produce insulin, or it’s unable to use it in a way that’s sufficient enough to maintain glucose at a healthy level in the bloodstream. Irregular or unstable glucose levels can cause a huge array of serious, life-threatening conditions, which we talk about in detail in this article.

    In regard to CBD oil for diabetes, there are two main things to consider in order to determine the degree of viability that the drug may have on the increasingly-prevalent disease:

    Major Considerations When Using CBD Oil for Diabetes


    • In what ways (if any), does CBD work to improve either the function and/or production of insulin?
    • In what ways might CBD work to alleviate the spectrum of side effects caused by irregular blood sugar levels?

    Here, in the hopes of shedding some light on why CBD oil for diabetes has gained such popularity among patients and physicians alike, we talk about recent research publications that have directly addressed both of these questions.

    Before Discussing CBD for Diabetes, Let’s Talk about What Diabetes Is

    To elaborate on the processes we explained in the introduction, diabetes is a disease wherein the body is unable to properly transfer the glucose from food into energy sources for cells.

    And of course, without energy sources, the body’s cells (which are responsible for every functional mechanism of life) will be unable to carry out the requisite pathways needed to survive.

    Without blood glucose regulation, cells are unable to carry out requisite pathways needed for survival. Can CBD help to reverse the adverse physiological effects of diabetes?

    In the case of Type 1 diabetics (who make up about 5% of the diabetic population), the body is no longer able to produce insulin, the key hormone it needs to transfer glucose molecules from the bloodstream into cells. This is generally due to an autoimmune attack on the pancreas – the organ responsible for producing insulin. Type 1 diabetes usually arises in children or young adults who contract a pancreas-attacking virus, and other than perhaps a genetic predisposition, there are not many specific risk factors.

    Type 2 diabetes is a more complex form of the disease wherein the body still produces insulin, but it either doesn’t produce enough of it, or the cells become resistant to its physiological pathways. Either way, the resulting effect is similar to that of Type 1 diabetes, wherein the underlying issue is a general inability to control blood glucose.

    Also, Type 2 diabetes is a far more prevalent form of the disease; it is estimated to affect over 400 million people worldwide, or between 90 and 95% of the total diabetic population.

    Additionally, far more risk factors are associated with Type 2 diabetes than there are with Type 1. Several of the most prominent of these factors include:

    Type 2 Diabetes Risk Factors:

    • Weight (obesity increases risk greatly)
    • High sugar diets (combined with inactivity)
    • Family history and genetics
    • Ethnicity (African-Americans, Latinos, and Native Americans are especially susceptible, though the reason is unclear)
    • Age (people over 45 are far more likely to develop diabetes)

    Conventional Treatment Methods for Diabetes (CBD Not Included)

    In both Type 1 and Type 2 diabetes, an inability for the body’s cells to absorb glucose results in it building up to dangerously high levels in the bloodstream. This results in the severe, potentially life-threatening symptoms that we most often associate with the disease. Some of these symptoms include:

    • Heart and blood vessel disease
    • Nerve damage
    • Stroke
    • Kidney disease
    • Vision problems

    In short, there aren’t many areas of the body that the physiological effects of diabetes do not impact, and unless the disease is monitored closely on a daily basis, the average diabetic will have a lifespan between 10 and 15 years shorter than average.

    Fortunately, conventional medications have gotten to the point where diabetics – if they keep track of their glucose levels rigorously and maintain an appropriate diet – can lead a rather normal lifestyle.

    Diabetes Treatment Options

    Since they can’t produce it on their own, most Type 1 diabetics use insulin either in the form of shots that they have to self-administer or in the form of a pump which automatically monitors blood glucose and injects the hormone as needed.

    While these forms of treatment are state of the art, they’re by no means 100% effective; even the most responsible of diabetics can find it difficult to avoid the dangerous consequences of irregular glucose levels.

    Even state-of-the-art diabetes treatments are not 100% effective in maintaining healthy blood glucose. How might CBD compare to conventional treatment options?

    Not to mention, without top of the line health insurance, treatments like insulin pumps are far too expensive for the average individual to consider. Most, in fact, have to take blood from their finger to monitor sugar levels and self-administer insulin shots through hypodermic needles.

    In the case of Type 2 diabetes, individuals who are able to get by without having to take insulin shots will most likely need a pharmaceutical drug like Metformin or Avandia, which aids in the ability to properly regulate glucose.

    However, as is far too common with these kinds of prescription meds, a range of severe side effects is often produced, as is a monthly medical bill that can be as cumbersome as the side effects themselves.

    This is why many diabetics in recent years have been more than willing to try alternative treatment options like CBD oil. Even if CBD can replace just one of their prescription medications – or even reduce the requisite doses – it’s generally more than worth it.

    Not to mention, the general improvement in quality of life for some diabetics that have added CBD to their treatment regimen has been significant.

    CBD Oil for Diabetes: What the Research Has Shown

    As we mentioned earlier, in the world of medicine, anecdotal evidence can only go so far. Regardless of the fact that many diabetics use CBD oil every day of their lives to help manage their condition, most physicians are wary to recommend it as a treatment because they can’t point to the exact physiological reasons as to why it’s beneficial.

    Fortunately, along with its potential to help with nervous disorders, CBD for diabetes has been a pretty well-researched area of medical cannabis.

    Studies on CBD and Diabetes

    Dr. Raphael Mechoulam, a research scientist from the Hebrew University of Jerusalem, points to the fact that naturally-occurring CBD receptors occur throughout the human body – from the brain and nervous tissues to organs, endocrine glands, and immune cells.

    And one of the organs where he’s found the receptors to be highly prevalent? The pancreas.

    Naturally-occurring CBD receptors occur throughout the human body: in the brain, nervous system, and crucially for sufferers of diabetes – in the islet cells of the pancreas.

    In fact, researchers have found endocannabinoid receptors (namely CB-1 receptors) specifically in the organ’s islet cells – the exact location where insulin is produced. What’s more, they have suggested that the stimulus of these receptors in the islet cells may have links to insulin production.

    Now, regardless of how intriguing the research is, we are by no means saying that endocannabinoid receptors are directly responsible for the production of insulin, or that CBD is a cure for diabetes in any way shape or form. While it’s possible that the receptors may play a crucial role in the production of insulin, much more research needs to be done in order to pinpoint the physiological mechanisms and exact chemical pathways that are responsible for doing so.

    We will say, though, that preliminary studies on CBD for diabetes have been so promising that it’s led to the American Journal of Medicine’s Dr. Joseph Alpert to call on the DEA and the National Institute of Health (NIH) for increased funding and collaboration on continued research.

    Can CBD Help Treat Underlying Symptoms of Diabetes?

    What’s even more concrete than research on CBD’s potential role in insulin production, though, is research on the compound’s ability to help lessen the symptoms of and even prevent some of the common medical conditions we associate with diabetes.

    One of the most prominent factors associated with the development of insulin resistance in Type 2 diabetes includes chronic inflammation related to obesity. The excessive presence of fatty tissue in obese Type 2 diabetics drastically limits the efficiency of glucose metabolism, which in turn results in high levels of sugar building up in the bloodstream.

    It is possible that the anti-inflammatory properties of CBD may be able to provide side-effect free therapy for both Type-1 and Type-2 diabetes patients.

    Nerve damage is another condition that commonly affects diabetes. In many instances, diabetics will have limited sensation in their lower extremities. This is due to nerve damage, which can lead to diabetics being unaware of injuries due to lack of sensation, which leads to an increased risk of infection. CBD happens to be a federally-patented neuroprotectant which may help prevent the diabetes-induced damage.

    Likewise, there have been dozens of publications that have shown great promise in the role of CBD as a treatment for diabetes, including studies on retinopathy (a disorder of the eyes) and diabetic cardiovascular dysfunction.

    In short, the medical potential and therapeutic benefits of CBD oil are promising; many diabetics use it daily to improve their overall quality of life, and thousands more will continue to do so in the future in light of increased research and improved information.

    Lastly, on a side note, it’s important to point out that CBD oil will not get you high – unlike whole-plant marijuana, it contains hardly any THC, which is the cannabinoid responsible for the psychoactive properties of the drug.

    Final Thoughts on CBD, Diabetes, and Future Treatment Options

    CBD oils can range in terms of their overall concentrations of the active cannabinoid; in other words, not all tinctures are the same, and different dosages will likely be necessary depending on the specific oil that you end up using (although the proper dosage should always be labeled on the bottle).

    Likewise, CBD oil is no guaranteed solution for all diabetics; while some patients have found it highly therapeutic, it will ultimately be more effective for some individuals than it is for others. As is always the case, it’s important to do your own research, and if possible, speak with a professional about some possible tinctures that may be appropriate for you and your specific condition.

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    Diabetes is a serious condition that affects over 422 million people across the world. It’s also one of the leading causes of death, killing millions each year. It’s characterized by problems involving your body converting sugar (or glucose) into energy.

    You see, when you’re healthy and you eat, your pancreas produces a hormone called insulin. Insulin helps to transport glucose molecules across cell membranes and into your cells to be used as energy. Insulin also helps your body store energy as glucose in your muscles, fat cells, and liver to be used at a later date, as and when you need it.

    Diabetics have trouble either producing insulin (Type 1 diabetes) or utilizing insulin (Type 2 diabetes). Type 2 diabetes is a lot more common, making up between 90 and 95% of all diabetics. Risk factors for Type 2 diabetes include weight, age, activity-levels, sugar intake, and genetics.

    CBD works through various pathways within the body to affect your physiology in a number of ways. Some of these are useful in treating and preventing diabetes:

    • Anti-inflammation

    Along with numerous other health benefits, CBD has been found to be a potent anti-inflammatory. And chronic inflammation is known to play a vital role in the development of insulin resistance and type 2 diabetes. The anti-inflammatory properties of CBD, therefore, could offer a safe and natural way to reduce the inflammation that leads to diabetes. This means CBD could help reverse or prevent Diabetes.

    • Improved circulation

    Nerve damage is a major problem for sufferers of diabetes. It is caused by poor blood circulation and in extreme cases can result in amputations, most commonly of the leg(s). CBD has been shown to improve blood supply to dead body tissue by up to 30%.

    • Improved immune function and metabolism

    The benefits of CBD for diabetes does not end there, however. The non-intoxicating compound has also been shown to positively affect the immune system and sugar metabolism, as well cell growth and heart function – all with minimal side effects.

    There are quite a few more studies pointing to the value of CBD in treating diabetes and its related conditions. And while most treatments for diabetes can only manage the symptoms (like insulin injections), thanks to its benefits on numerous bodily functions, CBD may actually suppress, reverse and perhaps even cure the disease.

    This is not just conjecture. There is also research to back up these claims. A lot of which has been conducted by preeminent cannabis researcher Dr Raphael Mechoulam from the Hebrew University of Jerusalem, who actually discovered CBD. This 2006 study by Mechoulam, for example, found that administration of CBD lowered the overall incidence of diabetes in lab rats.

    Another way that CBD may help treat and prevent diabetes, Dr Mechoulam theorizes, is through cannabinoid receptors (known as CB1 and CB2) located in the pancreas. Stimulation of the CB1 receptor has been shown to enhance insulin and glucagon secretion, while CB2 activation lowers glucose-dependent insulin secretion – both advantageous effects in diabetics or pre-diabetics.

    CBD Oil for Diabetes?

    Don’t fall for the hype. Here’s what the science and the experts have to say about cannabidiol oil (CBD) and your blood sugar. Part 1 in a series of OnTrack Diabetes reports. Written by Sari Harrar 34

    CBD is turning up in everything from beauty products like lip balm and mascara to soda, coffee, infused waters and alcohol, too. (Photo: Unsplash)

    Claims that cannabidiol oil—widely known as CBD oil or hemp oil—can help control blood sugar for people with Type 1 and Type 2 diabetes or even reverse diabetes are all over the Internet.

    A quick Google search of the terms “CBD Oil” and “Diabetes” turns up 2.9 million hits, with promises and testimonials that the compound cannabidiol in this hemp- or marijuana-based oil could “stabilize blood sugar1”, “improve insulin resistance2 ”, “decrease the need for insulin3” and even “suppress, reverse and perhaps cure the disease.4″

    Trouble is, there’s no proof it can do any of those things.

    “I don’t know that I would recommend CBD oil for diabetes,” notes integrative medicine doctor Taz Bhatia, MD, of Atlanta, Georgia, author of the books Super Woman RX and What Doctors Eat. “CBD is showing promise as a pain-reliever, an epilepsy treatment, and for wasting disease associated with cancer. It may help with neuropathic pain in diabetes. I think it is ok to try it, but don’t skip or cut back on diabetes medications.”

    Eileen Konieczny, RN, past president of the American Cannabis Nurses Association and author of the book Healing with CBD: How Cannabidiol can Transform your Health without the High (Ulysses Press, September 18, 2018) agrees. “I have not witnessed blood sugar control or management with CBD alone,” Konieczny told On Track Diabetes in an interview. “CBD clearly will help with the inflammation that accompanies diabetes and in that way a very helpful addition.”

    It may also ease the pain of peripheral neuropathy, she says. But people with diabetes shouldn’t expect it to lower their glucose levels or their A1Cs. “I have never seen anyone stop needing their diabetes medications because they started using CBD or cannabis,” she says.

    What Research Really Says

    Unlike marijuana, the compound cannabidiol won’t get you high even though it’s derived from cannabis. But product sales and interest in CBD are hitting new heights. In June, the FDA approved Epidiolex (cannabidiol), the nation’s first drug derived from marijuana, for two rare forms of epilepsy—Lennox-Gastaut syndrome and Dravet syndrome5.

    Over-the-counter and Internet sales of non-prescription CBD oil are expected to rise from $190 million in 2017 to $626 million by 2022 according to the Hemp Business Journal’s State of Hemp 2018 report6.

    CBD is also turning up in everything from beauty products like lip balm and mascara to sodas, alcohol, and infused waters.

    CBD’s got real potential in a wide variety of health conditions. There are currently more than 75 human studies of cannabidiol that are active, recruiting volunteers or in planning stages for conditions ranging from seizures to anxiety, post-traumatic stress disorder, Crohn’s disease, heart failure, Parkinson’s disease, bipolar depression, and cocaine dependence.7

    Not one focuses on diabetes.

    In fact, one of the only studies to ever look directly at the effects of cannabidiol on blood sugar and insulin levels in people with diabetes found no benefits at all.8 Published in the journal Diabetes Care in October of 2016, this British study compared the effects of CBD and another cannabis compound (tetrahydrocannabivarin (THCV)) on blood sugar, insulin sensitivity, HDL cholesterol and other markers in 62 people with type 2 diabetes.

    They took one of the compounds, or a combination of the two, daily for 13 weeks. The result: While THCV reduced blood sugar a little, CBD didn’t affect blood sugar levels. (CBD did seem to cause small changes in resistin, a protein that boosts inflammation and may be involved in insulin resistance; and glucose-dependent insulinotropic peptide hormone that stimulates insulin release.) “But there were no detectable metabolic effects,” the researchers concluded.

    The research had been supported by the UK drug company GW Pharmaceuticals, which went on to develop Epidiolex for seizure disorders. In April 2017 the company, which specializes in the development of cannabidiol-based medicines, announced that it was no longer researching its CBD compound for diabetes “due to negative data in diabetes.”9

    So what about all the research cited online suggesting blood sugar benefits? Some mis-state the results of the UK study. All link readers to small studies in animals, with results that have not been tested or not been replicated in people. Many laud work done in Israel a decade ago, when 68% of diabetes-prone mice who got CBD didn’t develop blood sugar problems.10

    What the FDA Says

    Between 2015 and 2018, the US Food and Drug Administration sent warning letters to companies that marketed CBD products, over claims and testimonials that oils and other products could treat diabetes and other conditions—including cancer. The FDA also warned that in some cases, lab tests showed that the products contained no CBD.

    You won’t find those unfounded treatment claims and miracle-cure testimonials on product websites anymore. But they are turning up more and more frequently on other websites. When the drug Epidiolex won approval in the US this summer, FDA Commissioner Scott Gottlieb, MD, warned consumers about the dangers this could pose. “The promotion and use of these unapproved products may keep some patients from accessing appropriate, recognized therapies to treat serious and even fatal diseases,” Dr. Gottlieb said in a statement.

    “The FDA has taken recent actions against companies distributing unapproved CBD products. These products have been marketed in a variety of formulations, such as oil drops, capsules, syrups, teas, and topical lotions and creams. These companies have claimed that various CBD products could be used to treat or cure serious diseases such as cancer with no scientific evidence to support such claims. We’re especially concerned when these products are marketed for serious or life-threatening diseases, where the illegal promotion of an unproven compound could discourage a patient from seeking other therapies that have proven benefits.”11

    Dr. Bhatia says that while CBD oil can have an important role to play in medicine, its difficult finding unbiased information. “The controversy surrounding cannabis has to do with the tug of war between medical purpose and recreational use—not to mention big money,” she notes on her website. “I think for now it is best to try it for the conditions recommended. For example—epilepsy, pain, Crohn’s disease or Inflammatory Bowel Disease,” she told On Track Diabetes.

    “We are using CBD without THC for chronic inflammatory conditions as well.” If you still want to give it a try, do your homework to determine if it’s safe for you. And Dr. Bhatia says you should look for proof it’s helping—and not change your existing medications. “Try it for three months,” she says. “But don’t cut back on diabetes medications.”

    To learn more about participating in clinical trials, go to clinicaltrials.gov.

    Updated on: December 19, 2018 View Sources

  1. “FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy”. US Food and Drug Administration, June 25, 2018. URL: https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm611046.htm
  2. Search of clinicaltrials.gov on September 23, 2018.
  3. “Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study.” Jadoon et al. Diabetes Care 2016;39:1777–1786
  4. “GW Pharmaceuticals Company outlook: Leaving clinical risk behind.” April 2017.
  5. “Cannabidiol lowers incidence of diabetes in non-obese diabetic mice” Weiss et al. Autoimmunity. 2006 Mar;39(2):143-51and “Cannabidiol Arrests Onset of Autoimmune Diabetes in NOD Mice” Weiss et al. Neuropharmacology. 2008 January ; 54(1): 244–249.
  6. Statement by FDA Commissioner Scott Gottlieb, M.D., on the importance of conducting proper research to prove safe and effective medical uses for the active chemicals in marijuana and its components June 25, 2018. US Food and Drug Administration. URL: https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm611047.htm

Continue Reading CBD Oil: What to Know Before You Try It

Can CBD Oil Help Treat Diabetes?

Type 1 and type 2 diabetes affect people of all ages and backgrounds. While there is currently no cure for diabetes, its symptoms can be treated with a combination of medications and lifestyle changes.

Cannabidiol (CBD) oil is not a substitution for common anti-diabetic medications and insulin, but it may help to alleviate bothersome symptoms. Research continues to find possible CBD oil benefits for diabetics.

To understand how CBD may treat diabetes symptoms, it’s first important to understand the disease itself.

Diabetes Type 1 vs Type 2

Diabetes occurs when the body cannot make sufficient amounts of insulin, resulting in elevated blood sugar. Type 1 and type 2 diabetes are the most common types of diabetes, with 10 percent of people with diabetes diagnosed as type 1 and 80-90 percent diagnosed as type 2.

Gestational diabetes is a third form of diabetes occurring during pregnancy. Gestational diabetes disappears after the baby is born, but it can be a predictor of type 2 diabetes later in life.

Type 1

Unlike type 2, type 1 diabetes is unpreventable. Type 1 occurs when a person’s immune system attacks their insulin-producing pancreas cells. Previously known as “juvenile diabetes,” type 1 can happen in both children and adults.

If you have type 1 diabetes, then you may experience these symptoms:

  • Excessive thirst and urination
  • Excessive hunger
  • Fatigue
  • Weight loss
  • Blurred vision

More severe symptoms, known as diabetic ketoacidosis, include:

  • Dry skin
  • Fruity-smelling breath
  • Nausea or stomach pain
  • Shortness of breath
  • Confusion and loss of focus

Type 2

When you think of diabetes, you most likely think of type 2. This form of diabetes is associated with obesity and lifestyle choices and therefore occurs more often in adults. It is characterized by insulin-resistance and insulin deficiency.

If you have type 2 diabetes, you may experience the following symptoms:

  • Excessive thirst and urination
  • Excessive hunger
  • Fatigue
  • Blurred vision
  • Numbness or tingling in hands and feet
  • Sores that don’t heal
  • Weight loss

Type 2 diabetes can also lead to more serious health issues as the disease progresses, such as:

  • Heart disease
  • Stroke
  • Kidney disease
  • Eye disease
  • Dental and gum diseases
  • Nerve damage
  • Dementia
  • Depression
  • Some cancers

How Does CBD Work?

CBD oil is a cannabinoid found in the hemp and cannabis plants, and its chemical makeup is similar to tetrahydrocannabinol (THC). Unlike THC, however, CBD does not have mind-altering effects—a major part of its growing appeal for all ages.

Both THC and CBD affect the body’s endocannabinoid system (ECS), but CBD affects different cannabinoid receptors. So, how does this talk of the ECS relate to the effect of CBD on diabetes? The ECS plays a role in food intake and energy stability, and scientists have associated an overactive ECS with obesity and type 2 diabetes. CBD’s impact on the ECS system may play a role in managing hyperglycemia, inflammation, and other byproducts of diabetes as a result of its activity at specific receptors.

The compound’s unique properties lend themselves to a wide range of treatments. CBD oil benefits are often touted for many conditions, both related and unrelated to diabetes:

  • Inflammation
  • Chronic pain
  • Nausea
  • Anxiety and depression
  • Seizures
  • Sleep disorders

CBD oil can be consumed in tablets, sublingual drops, on skin (transdermal) and more. Speak to a healthcare professional with CBD experience to figure out the correct dosage for your body.

CBD Side Effects

Side effects are a possibility with consumption of any substance, natural or otherwise. CBD oil can also interact with other drugs, so it is important to speak to your doctor before using CBD to treat symptoms of diabetes.

You may experience the following side effects when consuming CBD:

  • Low blood pressure
  • Nausea
  • Fatigue
  • Weight or appetite changes
  • Diarrhea
  • Dry mouth

Current Research on CBD Oil as a Treatment for Diabetes

Research on CBD and diabetes stretches beyond just blood sugar. There are many facets of diabetes that may benefit from CBD oil, from physical symptoms to depression. However, interesting diabetes-specific research has come to light.

Treating Diabetes-Related Inflammation

A 2019 study on diabetic rats showed improved memory performance and reduced inflammation after 30 daily doses of CBD at 10 mg. The study comes after a previous report that diabetes and aging work together to increase inflammation and memory loss in rats with cerebral hypoperfusion (i.e. weak blood flow to the brain).

An earlier study suggests that CBD may reduce early pancreatic inflammation in type 1 diabetes. The study also cites previous evidence of cannabidiol lowering incidences of diabetes in non-obese diabetic mice.

In addition, diabetic retinopathy, which causes blindness in adults, may be managed with cannabidiol. It’s possible that CBD acts as an antioxidant, inhibiting reuptake of adenosine and thereby reducing retinal inflammation. Further clinical studies are required to support this theory.

Treating Insulin Resistance

A double-blind study in animal models also found that subjects treated twice daily with 100 mg of CBD had lower concentrations of resistin. An increased level of resistin is connected with obesity and insulin resistance. The study implies that CBD may have some impact on insulin resistance.

Despite current research, there is no evidence that CBD can cure diabetes or regulate blood sugar in a way that replaces insulin treatments, statins and other anti-diabetic medications. Yet continued research gives new insight into CBD oil benefits for improving treatment outcomes.

Is CBD Oil Legal?

Currently, CBD is not legal on the federal level, but it may be legal in your state. With the legalization of hemp, however, the future looks bright for CBD. CBD will become more readily available, and this could be good news for diabetic individuals looking to experience the benefits of CBD oil.

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